2015 American Transplant Congress
Single Nucleotide Polymorphisms (SNPs) Associated With Acute Rejection in European American Kidney Transplant Recipients: A Genome Wide Association Study (GWAS)
Purpose: Acute rejection (AR) is associated with increased risk of allograft loss. Therefore, we conducted a GWAS to determine SNPs associated with AR in a…2015 American Transplant Congress
Outcomes of Live Kidney Donors Who Develop End Stage Renal Disease
Kidney donors can develop ESRD after donation, but the outcomes of those who do remain poorly characterized.Methods: Using USRDS and SRTR data, we compared access…2015 American Transplant Congress
Comparison of Markers of Inflammation Between Dialysis Patients With and Without Failed Kidney Allograft
BACKGROUND: The rates of morbidity and mortality in patients with a failed kidney transplant are higher than dialysis patients who had never been transplanted. The…2015 American Transplant Congress
Antibody-Mediated Rejection Is Associated With Higher Serum Levels of CXCL13 and CCL21 in Renal Transplant Patients and Altered By Bortezomib/Rituximab Treatment
In renal transplant patients (pts), B- and plasma cells (PC) are crucial for donor-specific HLA antibody (DSA) formation. The underlying mechanisms, which lead to B…2015 American Transplant Congress
Cognate Events in Antibody- Vs. T Cell-Mediated Rejection: A Molecular Perspective
AIM: The cognate event in antibody-mediated rejection (ABMR) is NK cell FcR engagement; T cell mediated rejection (TCMR) uses TCR engagement. Understanding the molecular changes…2015 American Transplant Congress
100 Protocol Renal Allograft Biopsies at 10 Years: First Look at the Tacrolimus Era
This study examined late renal allograft injury in the Tacrolimus era in 10-yr protocol biopsies (Bx).Methods One hundred 10-yr protocol allograft bx were assessed using…2015 American Transplant Congress
Lessons Learned from the Clinical Use of Normothermic Regional Perfusion (nRP) in Uncontrolled Donation After Circulatory Death (DCD)
The national protocol for the uDCD program restricts donor age < 55 y, no flow period < 30 min and total warm ischemia time (WIT)…2015 American Transplant Congress
Maintaining Immunosuppressive Treatment After Early Allograft Nephrectomy Does Not Reduce the Risk of Anti-HLA Allo-Sensitization
BackgroundAnti-HLA immunization is greatly increased after early kidney-allograft failure, even if the graft is removed within a few hours post-transplantation. The aim of our study…2015 American Transplant Congress
Banff Criteria Are Inadequate to Assess Chronic Renal Allograft Injury 10 Years Post-Transplantation
Background: The Banff criteria have been developed to assess acute and chronic injury in renal allografts. However, the criteria have been based on biopsies for…2015 American Transplant Congress
Evolution of GFR Outcomes During the First Year of Transplant According to the Kidney Donor Risk Index Transplantation in México. The Experience of a Single Center
Several scoring systems have been proposed to evaluate the quality of kidneys from deceased donors (DD). Recently, Kidney Donor Risk Index (KDRI) was introduced in…