ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2015 American Transplant Congress

    Age-Specific Graft Failure Rates in Pediatric Liver Transplant Recipients

    B. Foster,1 M. Dahhou,1 X. Zhang,1 V. Dharnidharka,2 J. Conway,3 V. Ng.4

    1Pediatrics, Research Institute of the McGill Univ. Health Centre, Montreal, QC, Canada; 2Pediatrics, Washington Univ., St. Louis, MO, Central African Republic; 3Pediatrics, Stollery Children's Hospital, Edmonton, AB, Canada; 4Transplant and Regenerative Medicine Center, Hospital for Sick Children, Toronto, ON, Canada.

    Graft failure risk peaks during emerging adulthood (18-25 y) in kidney transplant recipients. The association between age and graft failure risk in liver transplant recipients…
  • 2015 American Transplant Congress

    Timing of Pregnancy and Risk of Kidney Allograft Failure

    C. Rose, O. Johnston, A. Mehrotra, C. Kennedy, T. Myint, E. Hendren, J. Gill, J. Gill.

    Division of Nephrology, University of British Columbia, Vancouver, BC, Canada.

    The optimal timing of pregnancy after kidney transplantation remains uncertain. In this analysis of 23,981 female first-kidney only transplant recipients of child-bearing age (15-45 years),…
  • 2015 American Transplant Congress

    A Distinct Glomerular Complement Deposition Pattern in Transplant Glomerulopathy

    P. Verghese, R. Reed, A. Matas, Y. Kim.

    University of Minnesota, Minneapolis.

    While many patients with transplant glomerulopathy (TG) have donor-specific antibodies, the lack of C4d deposition in the peritubular capillaries (ptc-C4d) in some cases has caused…
  • 2015 American Transplant Congress

    Donor Microbiota and Its Contribution for the Development of Primary Graft Dysfunction Following Human Lung Transplantation

    Z. Xu,1 R. Schuessler,1 N. Steward,1 R. Hachem,2 E. Trulock,2 A. Patterson,1 D. Kreisel,1 T. Mohanakumar.1

    1Surgery, Washington Univ Sch of Med, St. Louis, MO; 2Medicine, Washington Univ Sch of Med, St. Louis, MO.

    Background: The microbiome of the donor lung will be imported to the recipient, and its role in allograft immunity remains speculative. The aims of this…
  • 2015 American Transplant Congress

    Can Post-Transplant C-Peptide Be Used as an Indicator of Pancreas Graft Failure?

    R. Carrico,1 J. Fridell,2 J. Odorico,3 R. Stratta,4 K. Tyler,1 S. Niederhaus,5 R. Kandaswamy,6 J. Fisher,7 O. Olaitan,8 M. Mujtaba.2

    1UNOS, Richmond, VA; 2Indiana Univ School of Medicine, Indianapolis, IN; 3Univ Wisconsin Hospital and Clinics, Madison, WI; 4Wake Forest Baptist Medical Center, Winston-Salem, NC; 5Univ of Maryland Medical System, Baltimore, MD; 6Univ of MN Medical Center, Minneapolis, MN; 7Scripps Green Hospital, La Jolla, CA; 8Rush Univ Medical Center, Chicago, IL.

    Background: The OPTN Pancreas Transplantation Committee is attempting to define pancreas graft failure and performed a study to determine if C-peptide corresponds to pancreas graft…
  • 2015 American Transplant Congress

    Impact of Preoperative MELD Score On Small for Size Syndrome in Living Donor Liver Transplantation

    S. Marubashi, A. Tomokuni, Y. Tomimaru, T. Asaoka, H. Wada, H. Eguchi, K. Umeshita, Y. Doki, M. Mori, H. Nagano.

    Surgery, Osaka University Graduate School of Medicine, Suita, Japan.

    Living donor liver transplantation (LDLT) has been expanded worldwide and the outcome of even adult-to-adult LDLT using left lobe reported to be equivalent to that…
  • 2015 American Transplant Congress

    Inflammation in Regions of Tubular Atrophy (IATR) Predicts Adverse Graft Outcome in Patients With Late Graft Dysfunction: A Multicenter Study

    J. Grande,1 R. Leduc,3 A. Matas.2

    1Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; 2Surgery, University of Minnesota, Minneapolis, MN; 3Biostatistics, University of Minnesota, Minneapolis, MN.

    Purpose: Inflammation in regions of tubular atrophy (IATR) is a risk factor for late graft loss. However, IATR is associated with inflammation in non-atrophic regions…
  • 2015 American Transplant Congress

    Respiratory Infections Following Lung Transplantation Leads to De Novo Development of Antibodies to Both Donor HLA and Lung Associated Self-Antigens and Increases the Risk for Bronchiolitis Obliterans Syndrome

    K. George,1 M. Gunasekaran,1 M. Sharma,1 F. Zhou,1 A. Limaye,3 R. Hachem,2 T. Mohanakumar.1

    1Surgery, Washington Univ, St. Louis, MO; 2Medicine, Washington Univ, St. Louis, MO; 3Medicine, Univ Washington, Seattle, WA.

    Background: It is accepted that lower respiratory tract infections (LRI) post lung transplantation (LTx) are a risk factor for the development of Bronchiolitis Obliterans Syndrome…
  • 2015 American Transplant Congress

    External Validation of Clinical Prediction Models of Patient and Graft Survival in a Canadian Cohort of Kidney Transplant Recipients

    S. Singh,1,2 D. Naimark,1,2,3 J. Victor,2 J. Kim.1,2,4,5

    1Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada; 2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; 3Division of Nephrology, Sunnybrook Health Sciences Center, Toronto, ON, Canada; 4Division of Nephrology and the Kidney Transplant Program, University Health Network, Toronto, ON, Canada; 5Division of Nephrology and the Renal Transplant Program, St. Michael's Hospital, Toronto, ON, Canada.

    Background: Several clinical prediction models (CPM) of patient and graft survival in kidney transplant recipients have been developed as tools to assist physicians in identifying…
  • 2015 American Transplant Congress

    Increased Late Graft Loss in Kidney Recipients With Serum Sickness Disease Following Anti-Thymocyte Globulin Induction: Relation With an Anti-Neu5Gc Response

    A. Salama,1,2 G. Couvrat-Desvergnes,1 M. Lorent,1,3 G. Evanno,1 L. Le Berre,1 P. Hruba,4 P. Vesely,5 P. Guerif,1 A. Nicot,1 J.-M. Bach,6 Y. Foucher,1,3 S. Brouard,1 S. Castagnet,7 O. Viklicky,4 M. Giral,1 J. Harb,1 S. Jean-Paul.1

    1INSERM UMR 1064, ITUN, CHU de Nantes, Nantes University, Nantes, France; 2Société d'Accélération du Transfert de Technologies Ouest Valorisation, Rennes, France; 3EA 4275 SPHERE, Biostatistics, Clinical Research and Pharmaco-Epidemiology, Nantes, France; 4Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 5Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic; 6IECM, EA4644 University/ONIRIS USC1383 INRA, ONIRIS, Nantes, France; 7EFS Pays de la Loire, Nantes, France.

    Anti-thymocyte globulins (ATG) are rabbit IgGs against human T cells widely used as induction treatment of kidney recipients. ATG can induce immune-complex diseases including Serum…
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