ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2016 American Transplant Congress

    HLA Antibody in Transplant Recipients During Transition from Paediatrics.

    S. Kaki,1 A. Lunn,2 J. Goodwin,3 T. Key,3 W. McKane.1

    1Renal, Sheffield Kidney Institute, Sheffield, United Kingdom; 2Renal, Queens Medical Centre, Sheffield, United Kingdom; 3Histocompatibility and Immunogenetics, National Health Service blood and transplantation, Sheffield, United Kingdom.

    Objective:Adolescent transplant recipients in transition from paediatric to adult units are known to be at high risk of graft failure. Detection of HLA antibody is…
  • 2016 American Transplant Congress

    Watch Out for the Guy with the Low EPTS Score: Nonadherence and Kidney Allograft Failure.

    A. Liu, K. Balabhadrapatruni, J. Augustine.

    Medicine, University Hospitals Case Medical School, Cleveland, OH.

    Background: Nonadherence is a known cause of rejection and kidney allograft failure. Our aim was to define risk factors for allograft loss related to nonadherence.…
  • 2016 American Transplant Congress

    Effect of Donor-Recipient Gender Mismatch in Liver Transplant Recipients: A Post-Hoc Analysis of the H2304 Study.

    L. Fischer, P. de Simone, G. Dong, P. Lopez, P. Bernhardt, F. Saliba.

    H2304 study group, Hamburg, Germany.

    Purpose: Donor-recipient gender mismatch may play a role in liver transplant (LTx) outcomes. Here we present the 24-month results from the post-hoc analysis of the…
  • 2016 American Transplant Congress

    Antibody Mediated Rejection and Mixed Acute Rejection: Long Term Results and Predictive Factors for Graft Loss Following Proteasome Inhibitor Therapy.

    A. Lichvar,1 A. Leino,1 S. Tremblay,1 B. Abu-Jawdeh,1 A. Govil,1 G. Mogilishetty,1 M. Cardi,2 J. Kremer,2 M. Cuffy,1,2 F. Paterno,1 A. Shields,1,2 D. Witte,1 R. Alloway,1 E. Woodle.1

    1U of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati.

    Purpose: Proteasome inhibitor (PI) therapy has been increasingly used to treated antibody mediated rejection (AMR) and mixed acute rejection (MAR). The purpose of this study…
  • 2016 American Transplant Congress

    The Increase of Serum MiR-142-3p Level in Acute Cardiac Rejection as a Reflection of Exosome-Mediated Genetic Exchange Between T Cells and Endothelial Cells.

    I. Dewi,1 Z. Hollander,2 B. McManus,2 O. Gidlöf,1 J. Öhman.1

    1Cardiology, Lund University, Lund, Sweden; 2PROOF Center of Excellence, Vancouver, Canada.

    IntroductionIn the recent years, microRNAs has emerged as the popular biomarker candidate in the field of solid organ transplantation due to their expression patterns reflect…
  • 2016 American Transplant Congress

    Pre-Transplant Risk Factors: Predicting Nonadherence and Rejection in Adult Liver Transplant Recipients.

    S. Lieber,1 J. Helcer,1 E. Leven,1 C. Knight,2 C. Wlodarkiewicz,2 A. Shenoy,1 E. Shemesh,1 S. Florman,3 T. Schiano,3 R. Annunziato.1

    1Icahn School of Medicine Mount Sinai Hospital, NY; 2Fordham University, NY; 3Recanati/Miller Transplant Institute Mount Sinai Hospital, NY.

    Purpose: The pre-liver transplant (LT) psychosocial evaluation aims to identify risk factors for immunosuppression nonadherence (NA) and poor post-LT outcomes. Despite broad support for these…
  • 2016 American Transplant Congress

    Outcomes with Steroids Alone for Biopsy-Proven Pancreas Transplant Rejection.

    S. Salahuddin,1 B. Astor,1 S. Parajuli,1 A. Djamali,1 J. Odorico,2 D. Mandelbrot.1

    1Department of Nephrology, University of Wisconsin, Madison, WI; 2Department of Surgery, University of Wisconsin, Madison, WI.

    There is little published data on the response of pancreas rejection to steroids alone. We reviewed 42 pancreas transplant recipients between 01/1997 and 12/2013 at…
  • 2016 American Transplant Congress

    Assessment of Molecular Mechanisms of Non-Transplant Cardiac Hypertrophy in Cardiac Allograft Hypertrophy – An Exploratory Gene Array Study of Myocardial Biopsy Samples.

    R. Araujo-Gutiérrez,1,2 S. Ibarra-Cortez,1,2 M. Park,1 J. Estep,1 G. Ashrith,1 B. Trachtenberg,1 G. Torre-Amione,1 K. Youker,1,2 A. Bhimaraj.1

    1Houston Methodist DeBakey Heart & Vascular Center, Houston, TX; 2Houston Methodist Research Institute, Houston, TX.

    Cardiac Allograft Hypertrophy (CAH) develops in up to 80% of patients as early as six months post-transplant, and is associated with decreased quality of life…
  • 2016 American Transplant Congress

    Urinary CXCL9 Protein as Biomarker for BK Polyoma Viremia.

    N. Sarabu,1 R. El-Rifai,2 J. Augustine,1 A. Padiyar,1 A. Huml,1 T. Young,1 V. Rodriguez,1 D. Hricik.1

    1Division of Nephrology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH; 2Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Introduction: BK infection is common in kidney transplant patients and can result in accelerated loss of allografts. Management involves empiric lowering of immunosuppression, which can…
  • 2015 American Transplant Congress

    B7-H1 Deficiency in Liver Allografts Leads to CD8-Mediated Acute Vascular Rejection

    M. Morita, D. Joyce, J. Fung, S. Qian, R. Fairchild, L. Lu.

    Immunology, Lerner Research Institute; 2General Surgery, Digestive Disease Institute, Clevland Clinic, Cleveland, OH.

    The liver is a unique organ in that it is accepted across complete MHC mismatch in allotransplantation in a number of species. The mechanisms behind…
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