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Articles tagged "Graft failure"

  • 2016 American Transplant Congress

    Torque Teno Virus – Inverse Association with Late Silent Antibody Mediated Kidney Allograft Rejection.

    G. Bond,1 M. Schiemann,1 F. Eskandary,1 H. Herkner,2 E. Puchhammer,3 R. Oberbauer,1 G. Böhmig.1

    1Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; 2Emergency Medicine, Medical University of Vienna, Vienna, Austria; 3Virology, Medical University of Vienna, Vienna, Austria.

    Clinical Problem and hypothesis: Antibody mediated rejection (ABMR) is a cardinal cause of late graft failure after kidney transplantation (KTX). A promising predictive diagnostic tool…
  • 2016 American Transplant Congress

    The Role of Obesity in Survival Outcomes of Liver Transplant Recipients with High MELD Score.

    S.-H. Chang,1 N. Carlsson,1 X. Liu,2 J. Wellen,3 J. Hagopian,4 T. Horwedel,4 T. Alhamad.5

    1Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis, St. Louis; 2Division of Biostatistics, Washington University in St. Louis, St. Louis; 3Department of Surgery, Washington University in St. Louis, St. Louis; 4Department of Pharmacy, Barnes Jewish Hospital, St. Louis; 5Renal Division, Washington University, St. Louis.

    Background:Obesity has become an epidemic in the United States. More than one third of adults are obese, defined as having body mass index (BMI) greater…
  • 2016 American Transplant Congress

    Primary Graft Failure following Cardiac Transplantation Is Associated with Elevated Pre-Transplant Levels of Pro-Inflammatory Factors.

    D. Chatterjee,1 K. Clerkin,1 K. Rogers,1 D. Mancini,1 Y. Naka,1 H. Takayama,2 K. Takeda,2 P. Colombo,2 G. Vlad,3 R. Vasilescu,3 B. Levin,4 M. Farr,1 S. Restaino,1 E. Zorn.1

    1Columbia University Medical Center, NY; 2Surgery, Columbia University Medical Center, NY; 3Pathology & Cell Biology, Columbia University Medical Center, NY; 4Biostatistics, Columbia University Medical Center, NY.

    Primary graft failure (PGF) is defined as severe ventricular dysfunction immediately following heart transplantation (HTx) requiring temporary mechanical circulatory support (MCS) such as VA ECMO…
  • 2016 American Transplant Congress

    Long-Term Death-Censored Graft Loss in the DeKAF Study.

    A. Matas,1 A. Fieberg,1 R. Leduc,1 F. Cosio,2 R. Gaston,3 R. Mannon,3 M. Cecka,4 D. Rush,7 B. Kasiske,5 S. Gourishankar,6 J. Connett,1 J. Grande.2

    1U of MN, Mpls, MN; 2Mayo, Rochester, MN; 3UAB, Birmingham, AB; 4UCLA, LA, CA; 5HCMC, Mpls, MN; 6U Alberta, Edmonton, AB, Canada; 7UMB, Winnipeg, MB, Canada.

    The aim of the Deterioration of Kidney Allograft Function study (DeKAF) was to identify and assess the pathologies of troubled kidney grafts, that is, those…
  • 2016 American Transplant Congress

    Functional Capacity Pre-Transplantation Measured by 6 Minute Walk Test and Clinical Outcomes.

    T. Alhamad,1 K. Lentine,2 S. Anwar,3 T. Maw,1 T. Horwedel,1 J. Peng,1 K. Saffaf,1 J. Hagopian,1 R. Delos Santos,1 A. Malone,1 D. Brennan.1

    1Washington University, St. Louis; 2Saint Louis University, St. Louis; 3Newcastle Hospital, Newcastle, United Kingdom.

    Background:The 6 minute walk is an inexpensive, low-technology test for measuring a patient's functional capacity and overall fitness. The utility of 6 minute walk test…
  • 2016 American Transplant Congress

    Outcomes for Liver Transplantation Using Organs from Donation After Cardiac Death Donors: A Single Center Experience.

    J. Vanatta, X. Zhao, V. Puri, R. Helmick, S. Nair, S. Satapathy, J. Eason.

    Transplantation, University of Tennessee/Methodist University Transplant Institute, Memphis, TN.

    Purpose: The use of donation after cardiac death (DCD) donors provides opportunity to help meet the demand for allografts needed for liver transplantation. However, concern…
  • 2016 American Transplant Congress

    Share35 Liver Allocation Is Associated with Increased Early Graft Failure Rate.

    T. Wong,1 N. Koizumi,2 J. Ortiz.3

    1Maricopa Medical Center, Phoenix, AZ; 2George Mason University, Arlington, VA; 3University of Toledo, Toledo, OH.

    Background: The implementation of Share35 liver allocation policy in June 2013 facilitated the increase in number of transplanted livers with less organ discards. Early analysis…
  • 2016 American Transplant Congress

    Natural History of Response to Wounding in Human Kidney Transplants.

    K. Famulski,1 J. Venner,2,1 J. Reeve,1 P. Halloran.1

    1University of Alberta, Edmonton, AB, Canada; 2University of Queensland, Brisbane, Queensland, Australia.

    In both primary kidney diseases and kidney transplants, the extent of fibrosis is a key indicator of stage, progression, and prognosis. Much debate focuses, however,…
  • 2016 American Transplant Congress

    A 30% Decrease in Post-kidney Transplant Estimated Glomerular Filtration Rate (eGFR) from 6 Mo-2 Y Is a Surrogate for 5 Y eGFR: Results from Clinical Trials in Organ Transplantation-(CTOT)-17.

    G. Faddoul,1 G. Nadkarni,1 D. Hricik,2 P. Heeger,1 CTOT17 Investigators.

    1Medicine and Recanati Miller Transplant Institute, Icahn School of Medicine, NY, NY; 2Medicine, Case Medical Center, Cleveland, OH.

    Predicting long-term kidney allograft outcomes using early clinical/biomarker data could guide individualized therapy. Emerging evidence in progressive native kidney disease indicates >30% decrease in eGFR…
  • 2016 American Transplant Congress

    Treatment of Late Antibody-Mediated Rejection: Observations from Clinical Practice.

    G. Einecke,1 J. Bräsen,2 A. Schwarz,1 H. Haller,1 F. Njau.1

    1Nephrology, Medical School of Hannover, Hannover, Germany; 2Pathology, Medical School of Hannover, Hannover, Germany.

    Antibody-mediated rejection (AMR) is a major cause of late renal allograft failure. The benefit of treatment of chronic ABMR is unknown. Currently there is no…
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