ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2017 American Transplant Congress

    Do Perioperative Blood Transfusions Influence Kidney Transplant Outcomes in the Modern Era?

    J. Lineen, J. Trac, Y. Li, O. Famure, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Background: Blood transfusions are a well-established risk factor for human leukocyte antigen sensitization in kidney transplant candidates. To date, relatively few studies have explored the…
  • 2017 American Transplant Congress

    Biomarkers of Epithelial-Mesenchymal Transition (EMT) in Chronic Allograft Nephropathy: Potential for Early Detection and Development of Novel Therapeutic Agents.

    S. Kanangat, R. Miller, S. Rezaeian, H. Eldib, D. Cimbaluk, C. Fhied, I. Kurbegovic-Skaljic, M. Prod, J. Borgia, M. Flaws, D. Castillo, R. DeCresce.

    Pathology, BioChemistry and Medical Laboratory Sciences, Rush University Medical Center, Chicago, IL

    Purpose: To detect markers and novel treatment targets related to fibrogenesis and eventual graft loss by focusing on Epithelial Mesenchymal transition (EMT) which requires understanding…
  • 2017 American Transplant Congress

    Cardiovascular Events Are a Substantial and Increasing Cause of Graft Loss in Liver Transplant Recipients.

    M. Sell, A. Mardis, I. Lee, B. O'Brien, C. Perez, A. Rogers, C. Mardis, N. Patel, J. Fleming, H. Meadows, N. Pilch, K. Chavin, D. Taber.

    Pharmacy, Transplant, MUSC, Charleston, SC

    Purpose: The overall 1- and 3- year graft survival rates following liver transplant are 89.1% and 79.9%, respectively. While these numbers have vastly improved, they…
  • 2017 American Transplant Congress

    Short- and Long-Term Graft Survival After Kidney Transplantation in Western Europe.

    M. Coemans,1 G. Verbeke, D. Anglicheau, O. Bestard, M. Giral, M. Naesens.1,2

    1Microbiology and Immunology, KU Leuven, Leuven, Belgium; 2Nephrology and Renal Transplantation, KU Leuven, Leuven, Belgium

    Background: Improvement of kidney survival after transplantation has mainly been studied in the American population. There, it was found that improvement mostly occurred on the…
  • 2017 American Transplant Congress

    Clinical Outcomes in Older Kidney Transplant Recipients. A Single Center Experience.

    L. Kamal, N. Hayde, P. Bedi, M. Lubetzky, M. Ajaimy, G. DeBoccardo, E. Akalin.

    Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, NY

    Background: We aimed to investigate the clinical outcomes of kidney transplant recipients 65 years and older.Methods: Between 1/2009 and 12/2014, 687 patients underwent a kidney…
  • 2017 American Transplant Congress

    Impact of Type of Kidney (Living vs. Deceased) on Urinary Podocyte Excretion Rate in Renal Allografts.

    A. Naik, D. Luan, D. Cibrik, M. Samaniego, K. Woodside, M. Chowdhury, S. Wang, R. Wiggins.

    U Michigan, Ann Arbor

    Aim: Long term allograft survival has not improved.Surveillance biopsy studies have demonstrated that chronic microcirculatory injury and progressive glomerulosclerosis are the most common histological finding…
  • 2017 American Transplant Congress

    Glycolytic and Glutaminolytic Metabolism Supports IL-15 Induced Inflammatory Response of Temra CD8 from Kidney Transplant Recipients.

    T.-M. Doan-Ngoc,1 G. Tilly,1 M. Yap,1 A. Caristan,1 L. Jacquemont,1 R. Danger,1 M. Cadoux,1 S. Bruneau,1 M. Giral,1 P. Guerif,1 B. Nicol,1 A. Garcia,1 D. Laplaud,1 S. Brouard,1 C. Pecqueur,2 N. Degauque.1

    1CRTI UMR1064, INSERM, Nantes, France; 2CRCNA UMR892, INSERM, Nantes, France

    Rational. We have recently shown that the accumulation of TEMRA CD8 in kidney transplant recipients (Tx) is associated with a higher risk of kidney dysfunction.…
  • 2017 American Transplant Congress

    Epigenetic Modifications in the Progression to Chronic Renal Allograft Injury.

    V. Bontha,1 D. Maluf,1 M. Dozmorov,2 K. Archer,3 L. Gallon,4 V. Mas.1

    1UVA, Charlottesville; 2VCU, Richmond; 3OSU, Columbus; 4NWU, Chicago

    Background: The renal allograft is exposed to a milieu of environmental/metabolic stimuli that trigger epigenetic modifications and thereby gene expression patterns which influence function and…
  • 2017 American Transplant Congress

    Bacteremia in Kidney Transplant Recipients: Incidence, Risk Factors, and Outcomes.

    S. Brar, Y. Wang, A. Cannitelli, Y. Li, O. Famure, S. Husain, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Background: Bloodstream infections or bacteremia is a serious complication after kidney transplantation. The incidence, risk factors, and outcomes of bacteremia among kidney transplant recipients have…
  • 2017 American Transplant Congress

    Urinary Concentration Ability in Kidney Transplant Patients as Predictor for CKD.

    P. Garcia-Garcia,1 A. Jarque,1 A. Rivero,1 A. Rodriguez,1 J. Gonzalez Posadas,1 M. Macia,1 V. Garcia Nieto,2 J. Navarro.1

    1Nephrology Service, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain; 2Pediatric Nephrology Unit, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain

    Urinary concentration is the result of a complex glomerulotubular mechanism, which culpits with the stimulation of aquaporins at the collector tubule, in response to vasopressin…
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