ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2017 American Transplant Congress

    Noninvasive Prognostication of Renal Allograft Failure Following BK Virus Associated Nephropathy – A Validation Study.

    E. Abuhelaiqa, C. Snopkowski, C. Li, J. Lee, T. Muthukumar, H. Yang, M. Suthanthiran, D. Dadhania.

    Transplant Medicine, Weill Cornell Medicine, NY, NY

    Introduction. Identification of kidney transplant (KTx) recipients at risk for graft loss following BKVN diagnosis may allow personalization of immunosuppressive protocols. Previous study demonstrated that…
  • 2017 American Transplant Congress

    Dysregulated Innate Immune Response Is a Robust Predictor of Allograft Injury and Survival Across All Transplanted Organs.

    T. Azad,1 M. Donato,1 L. Heylen,2 S. Shen-Orr,3 T. Sweeney,1 M. Naesens,2 P. Khatri.1

    1Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA; 2University of Leuven, Leuven, Belgium; 3Technion-Israel Institute of Technology, Haifa, Israel

    ObjectiveLate allograft failure is characterized by long-term cumulative effects of subclinical allograft injury. An optimal biomarker diagnoses acute rejection (AR), correlates with ongoing graft damage,…
  • 2017 American Transplant Congress

    Kidney Size Does Not Matter: Should the Decision to Split Pediatric En Bloc Donor Kidneys Be Based on Donor Weight Rather Than Kidney Length?

    A. Perry, J. Woloszyn, J. McVicar, J. Sageshima, R. Perez, C. Troppmann, C. Santhanakrishnan.

    Division of Transplant Surgery, University of California, Davis, Sacramento, CA

    Background: Deceased donor kidneys from pediatric donors have been used with good results. However, there is little consensus on the criteria used to safely split…
  • 2017 American Transplant Congress

    A UNOS Database Analysis of Patient Outcomes from Kidney Alone versus Simultaneous Kidney Liver Transplants Utilizing Matched Donor Pairs.

    T. Zens, J. Danobeitia, P. Stahler, G. Leverson, R. Redfield III, A. D'Alessandro, L. Fernandez.

    Surgery - Division of Transplantation, University of Wisconsin - Madison, Madison, WI

    Introduction: Renal grafts used in simultaneous kidney liver (SLK) transplants are allocated by arbitrary clinical criteria without entering the kidney allocation algorithm. The goal of…
  • 2017 American Transplant Congress

    Repeat Biopsies After the Diagnosis of BK Virus Associated Nephropathy: Importance of Integrating Clinical and Pathological Findings.

    C. Drachenberg,1 J. Papadimitriou,1 R. Ugarte,2 M. Mavanur,2 B. Thomas,2 C. Cangro,2 N. Costa,2 M. Weir,2 A. Haririan.2

    1Pathology, University of Maryland School of Medicine, Baltimore, MD; 2Medicine, University of Maryland School of Medicine, Baltimore, MD

    Early diagnosis of PV nephropathy(PyVAN) leads to overall improvements in the short term but sclerosing sequelae and risk for rejection (mainly antibody mediated) contribute to…
  • 2017 American Transplant Congress

    Risk Factors of Treatment Failure in Antibody Mediated Rejection.

    V. Pernin,1 I. Szwarc,1 T. Kanouni,2 V. Garrigue,1 J. Serre,1 S. Delmas,1 G. Mourad,1 M. Le Quintrec.1

    1Department of Nephrology, Dialysis and Transplantation, CHU Lapeyronie, Montpellier, France; 2Department of Hematology, CHU St ELoi, Montpellier, France

    Background: Antibody-mediated rejection (AMR) is recognized as the major cause of kidney allograft loss. Despite an aggressive treatment, prognosis is usually poor. The aim of…
  • 2017 American Transplant Congress

    Renal Function, Albuminuria, and the Risk of Death and Graft Loss After Kidney Transplantation.

    N. Lam,1 M. Tonelli,2 K. Lentine,3 B. Hemmelgarn,2 F. Ye,1 K. Wen,1 S. Klarenbach.1

    1University of Alberta, Edmonton, Canada; 2University of Calgary, Calgary, Canada; 3Saint Louis University, St. Louis

    In 2012, the KDIGO guidelines updated the classification system for chronic kidney disease to include albuminuria. Whether this classification system prognosticates adverse clinical outcomes among…
  • 2017 American Transplant Congress

    Liver Allograft Hepatitis and Graft Loss After Hepatitis C Clearance.

    D. Bruno, S. Brown, S. Hanish, J. LaMattina, W. Hutson, S. Kottilil, W. Twadell, R. Barth.

    Surgery, University of Maryland School of Medicine, Baltimore, MD

    Successful HCV therapies should improve inferior outcomes of liver transplantation (LT) for HCV cirrhosis. We hypothesize certain patients may be predisposed to heterologous immunity that…
  • 2017 American Transplant Congress

    Risk of Ischemic Biliary Injury Is Not Associated with Prolonged Hepatic Artery Ischemic Times During Liver Transplantation.

    E. Armenia,1 N. Schomaker,1 A. Kalra,1 J. Gralla,1 A. Truesdale,1 S. Biggins,2 T. Nydam,1 J. Burton.1

    1Univ. Colorado, Aurora, CO; 2Univ. Washington, Seattle, WA

    Biliary strictures after liver transplant (LT) are associated with increased patient morbidity and graft failure. AIM: To assess the association of duration of hepatic artery…
  • 2017 American Transplant Congress

    Microcirculation Inflammation in Kidney Allograft Biopsies.

    M. Giordani,1 M. Bedini Rocca,1 S. Groppa,1 C. Mombelli,1 S. Christiansen,2 M. Ocampo,1 G. Rosa Diez,1 N. Imperiali.1

    1Nephrology, Hospital Italiano, Buenos Aires, Argentina; 2Pathology, Hospital Italiano, Buenos Aires, Argentina

    Introduction: The Microcirculation Inflammation (IM) in kidney transplants is a strong predictor of graft loss inde-pedent of C4d and donor specific antibody(DSA)ObjetiveAnalysis of kidney allograft…
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