Articles tagged "Graft failure"

2022 American Transplant Congress
The Role of Donor Sex in Females Undergoing Repeat Kidney Transplant: Does Prior Donor Sex Matter?
S. Craig¹, K. Tennankore², A. J. Vinson²
¹Dalhousie University, Halifax, NS, Canada, ²Nova Scotia Health Authority, Halifax, NS, Canada
*Purpose: Female recipients of male donor kidneys are at increased risk for graft failure compared with all other donor-recipient sex pairings. The presumed mechanism relates…
2022 American Transplant Congress
Digital Spatial Profiling of Kidney Allograft Biopsies with Chronic Allograft Dysfunction in African American Transplant Recipients
C. R. Dorr¹, S. A. Elmer¹, B. Wu², B. Guo², J. Czyzyk², G. Crary³, G. Onyeaghala¹, W. Oetting², P. Jacobson², R. B. Mannon⁴, G. Agarwal⁵, J. Maltzman⁶, A. Matas², A. Israni³
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN, ⁴Medicine, University of Nebraska Medical Center, Omaha, NE, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Stanford University, Palo Alto, CA
*Purpose: Understanding tissue heterogeneity is important to identify the molecular and cellular mechanisms of kidney allograft loss in African American (AA) transplant recipients. Our aim…
2022 American Transplant Congress
Outcomes of Simultaneous Kidney Pancreas Transplantation in Patients with Type-1 and Type-2 Diabetes Mellitus
H. Shokouh-Amiri¹, M. S. Naseer², S. Badar¹, R. McMillan¹, D. Aultman¹, S. Tandukar¹, N. Singh¹, G. B. Zibari¹
¹John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, ²Transplant, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA
*Purpose: Advantages for type-2 diabetes mellitus (T2DM) patients receiving simultaneous kidney-pancreas transplantation (SKPT) as compared to kidney transplantation are shorter waiting times and availability of…
2022 American Transplant Congress
The Perspective of General Nephrologists Toward Transitions of Care and Management of Patients with Failing Kidney Allografts
T. Alhamad¹, H. Murad¹, D. Dadhania², M. Pavlakis³, S. Parajuli⁴, B. P. Concepcion⁵, N. Singh⁶, N. Murakami⁷, M. Casey⁸, M. Ji¹, M. Lubetzky⁹, E. Tantisattamo¹⁰, O. Alomar¹, A. Faravardeh¹¹, C. Blosser¹², A. Basu¹³, M. Molnar¹⁴, G. Gupta¹⁵, J. T. Adler¹⁶, D. Adey¹⁷, K. J. Woodside¹⁸, R. Parsons¹³, K. Lentine¹⁹
¹Wash U in St. Louis, Saint Louis, MO, ²Weill Cornell Med, New York, NY, ³Beth Israel, Boston, MA, ⁴U of Wisconsin, Madison, WI, ⁵Vanderbilt U, Nashville, TN, ⁶Northwell Health, Great neck, NY, ⁷Brigham and Women, Boston, MA, ⁸MUSC, Charleston, SC, ⁹Weill Cornell Medicine, New York, NY, ¹⁰UCI, Orange, CA, ¹¹SHARP, San Diego, CA, ¹²U of Washington, Seattle, WA, ¹³Emory U, Atlanta, GA, ¹⁴U of Utah, Salt Lake City, UT, ¹⁵VCU, Richmond, VA, ¹⁶Surgery, Brigham and Women, Boston, MA, ¹⁷UCSF, San Francisco, CA, ¹⁸U of Michigan, Ann Arbor, MI, ¹⁹Saint Louis U, Saint Louis, MO
*Purpose: Failing kidney allograft with subsequent return to dialysis is associated with high risk of morbidity and mortality. This project aimed to examine general nephrologist…
2022 American Transplant Congress
Effect of Immunosuppression Withdrawal After Graft Failure on Re-Kidney Transplantation Outcomes
J. Ahn¹, S. Sandal², S. Bae¹, D. Segev¹, M. McAdams-DeMarco¹
¹Johns Hopkins University, Baltimore, MD, ²McGill University, Montreal, QC, Canada
*Purpose: The risk and benefit of immunosuppression use after graft failure need to be addressed to improve patient and graft survival after their re-kidney transplantation…
2022 American Transplant Congress
Retransplantation in a High-Volume Institution: Historical, Socioeconomic and Survival Trends
D. von Ahrens, O. Sulimani, M. Holzner, M. Akhtar, S. Florman, A. Arvelakis
The Mount Sinai Hospital, New York, NY
*Purpose: Retransplantation for liver allograft failure is a challenge within the field. The evolution of organ allocation policy from Child to MELD in 2002 and…
2022 American Transplant Congress
Clinical Evolution of Patients with De Novo DSA After Kidney Transplantation
C. López del Moral¹, N. Lachmann², S. Hergovits², D. Stauch², A. Akifova³, M. Naik³, B. Osmanodja³, D. Schmidt³, K. Budde³
¹Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, ³Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany
*Purpose: De novo donor-specific antibodies(dnDSA) are related to antibody-mediated rejection(ABMR), but the evolution of patients after dnDSA is variable and not always ABMR and graft…
2022 American Transplant Congress
Four-Year Patient Survival After Simultaneous Pancreas-Kidney Transplantation According to Graft Status Using Kaplan-Meier Survival Method and Competing Risk Model
L. A. Alfaro¹, L. A. Viana¹, M. P. Cristelli¹, E. B. Rangel², R. Meirelles³, H. Tedesco¹, J. Medina¹
¹Renal Transplantation, Hospital do Rim - Fundação Oswaldo Ramos, Sao Paulo, Brazil, ²Federal University of Sao Paulo, Sao Paulo, Brazil, ³Kidney-Pancreas Transplantation, Hospital do Rim - Fundação Oswaldo Ramos, Sao Paulo, Brazil
*Purpose: Aim of this study is to compare the patient survival submitted to SPKT according to the status of graft losses, kidney, pancreas, or both…
2022 American Transplant Congress
Natural Antibodies Are Associated With Rejection And Long-term Renal Allograft Loss In A Multi-center International Cohort
S. B. See¹, X. Yang², C. Burger³, B. Lamarthée⁴, R. Snanoudj⁵, R. Shihab¹, D. S. Tsapepas⁶, P. Roy¹, S. Larivière-Beaudoin⁷, K. Hamelin⁷, A. Mendoza Rojas⁸, N. M. van Besouw⁸, A. Bartosic⁹, N. Daniel⁹, E. R. Vasilescu¹⁰, S. Mohan¹¹, D. Cohen¹¹, L. Ratner¹¹, C. C. Baan⁸, J. S. Bromberg⁹, H. Cardinal⁷, D. Anglicheau³, Y. Sun², E. Zorn¹
¹CCTI, Columbia University Irving Medical Center, New York, NY, ²Biostatistics, Columbia University Irving Medical Center, New York, NY, ³Necker Hospital, Paris, France, ⁴Necker-Enfants Malades Institute, Paris, France, ⁵Bicêtre Hospital, Paris, France, ⁶Surgery, Columbia University Irving Medical Center, New York, NY, ⁷CHUM, Montreal, QC, Canada, ⁸Erasmus MC, Rotterdam, Netherlands, ⁹Surgery, University of Maryland School of Medicine, Baltimore, MD, ¹⁰Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, ¹¹Medicine, Columbia University Irving Medical Center, New York, NY
*Purpose: Potentially harmful non-donor-specific human leukocyte antigen antibodies have been identified in renal transplantation, including natural IgG antibodies (Nabs) reactive to varied antigenic structures.*Methods: In…
2022 American Transplant Congress
Does Comprehensive Geriatric Assessment Impact Risk Assessment for Potential Kidney Transplant Patients?
J. Patel¹, S. Hussain², D. Mills¹, A. Edobor³, E. Walters³, J. Williams³, Y. Kyeso², J. F. Fung³, R. Barth³, D. Rubin⁴, M. Huisingh-Scheetz², M. Martinchek⁵, M. L. Madariaga³
¹Pritzker School of Medicine, University of Chicago, Chicago, IL, ²Medicine, University of Chicago Medicine, Chicago, IL, ³Surgery, University of Chicago Medicine, Chicago, IL, ⁴Anesthesia, University of Chicago Medicine, Chicago, IL, ⁵Medicine, Massachusetts General Hospital, Boston, MA
*Purpose: The clinical impact of the components of a comprehensive geriatric assessment (CGA) on kidney transplant decision making in older adults has not been investigated.*Methods:…