ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2018 American Transplant Congress

    Acute Murine CMV Infection Results in Loss of Intragraft CD73HIFR4HIPD1+ CD4 T Cells and Graft Rejection in Previously Tolerant Recipients

    A. Dangi,1 L. Zhang,1 X. Zhang,2 X. Luo.1,2

    1Division of Nephrology and Hypertension, Department of Medicine, Northwestern University, Chicago, IL; 2Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL.

    Background: Transplantation tolerance in human recipients has been achieved in recent trials. Nevertheless, the impact of highly prevalent and clinically relevant cytomegalovirus (CMV) infection on…
  • 2018 American Transplant Congress

    Scoring Transplant Glomerulopathy Using Morphometry: Correlation with Banff Criteria

    M. Morales, A. Denic, W. Park, B. Smith, M. Alexander, M. Stegall.

    William J.von Liebig Transplant Center, Mayo Clinic, Rochester, MN.

    Background: Transplant glomerulopathy (TG) is a prognostic marker for graft survival. Still, scoring TG using the Banff cg-score remains a challenge and no assessments in…
  • 2018 American Transplant Congress

    The Association between Transplant Glomerulopathy and Graft Outcomes among Patients Undergoing Kidney Transplantation: Results of a Meta-Analysis

    G. Kovács,1 G. Devercelli,2 Z. Vokó,1,3 T. Zelei,1 I. Hirji,2 P. Keown.4,5

    1Syreon Research Institute, Budapest, Hungary; 2Shire, Lexington, MA; 3Health Policy & Health Economics, Eötvös Loránd University, Budapest, Hungary; 4Syreon Corporation, Vancouver, BC, Canada; 5University of British Columbia, Vancouver, BC, Canada.

    Transplant glomerulopathy (TG) can lead to irreversible kidney damage. TG is recognized as a surrogate marker for poor outcomes, including graft failure and loss among…
  • 2017 American Transplant Congress

    Risk of Ischemic Biliary Injury Is Not Associated with Prolonged Hepatic Artery Ischemic Times During Liver Transplantation.

    E. Armenia,1 N. Schomaker,1 A. Kalra,1 J. Gralla,1 A. Truesdale,1 S. Biggins,2 T. Nydam,1 J. Burton.1

    1Univ. Colorado, Aurora, CO; 2Univ. Washington, Seattle, WA

    Biliary strictures after liver transplant (LT) are associated with increased patient morbidity and graft failure. AIM: To assess the association of duration of hepatic artery…
  • 2017 American Transplant Congress

    Microcirculation Inflammation in Kidney Allograft Biopsies.

    M. Giordani,1 M. Bedini Rocca,1 S. Groppa,1 C. Mombelli,1 S. Christiansen,2 M. Ocampo,1 G. Rosa Diez,1 N. Imperiali.1

    1Nephrology, Hospital Italiano, Buenos Aires, Argentina; 2Pathology, Hospital Italiano, Buenos Aires, Argentina

    Introduction: The Microcirculation Inflammation (IM) in kidney transplants is a strong predictor of graft loss inde-pedent of C4d and donor specific antibody(DSA)ObjetiveAnalysis of kidney allograft…
  • 2017 American Transplant Congress

    Do Perioperative Blood Transfusions Influence Kidney Transplant Outcomes in the Modern Era?

    J. Lineen, J. Trac, Y. Li, O. Famure, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Background: Blood transfusions are a well-established risk factor for human leukocyte antigen sensitization in kidney transplant candidates. To date, relatively few studies have explored the…
  • 2017 American Transplant Congress

    Biomarkers of Epithelial-Mesenchymal Transition (EMT) in Chronic Allograft Nephropathy: Potential for Early Detection and Development of Novel Therapeutic Agents.

    S. Kanangat, R. Miller, S. Rezaeian, H. Eldib, D. Cimbaluk, C. Fhied, I. Kurbegovic-Skaljic, M. Prod, J. Borgia, M. Flaws, D. Castillo, R. DeCresce.

    Pathology, BioChemistry and Medical Laboratory Sciences, Rush University Medical Center, Chicago, IL

    Purpose: To detect markers and novel treatment targets related to fibrogenesis and eventual graft loss by focusing on Epithelial Mesenchymal transition (EMT) which requires understanding…
  • 2017 American Transplant Congress

    Cardiovascular Events Are a Substantial and Increasing Cause of Graft Loss in Liver Transplant Recipients.

    M. Sell, A. Mardis, I. Lee, B. O'Brien, C. Perez, A. Rogers, C. Mardis, N. Patel, J. Fleming, H. Meadows, N. Pilch, K. Chavin, D. Taber.

    Pharmacy, Transplant, MUSC, Charleston, SC

    Purpose: The overall 1- and 3- year graft survival rates following liver transplant are 89.1% and 79.9%, respectively. While these numbers have vastly improved, they…
  • 2017 American Transplant Congress

    Short- and Long-Term Graft Survival After Kidney Transplantation in Western Europe.

    M. Coemans,1 G. Verbeke, D. Anglicheau, O. Bestard, M. Giral, M. Naesens.1,2

    1Microbiology and Immunology, KU Leuven, Leuven, Belgium; 2Nephrology and Renal Transplantation, KU Leuven, Leuven, Belgium

    Background: Improvement of kidney survival after transplantation has mainly been studied in the American population. There, it was found that improvement mostly occurred on the…
  • 2017 American Transplant Congress

    Clinical Outcomes in Older Kidney Transplant Recipients. A Single Center Experience.

    L. Kamal, N. Hayde, P. Bedi, M. Lubetzky, M. Ajaimy, G. DeBoccardo, E. Akalin.

    Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, NY

    Background: We aimed to investigate the clinical outcomes of kidney transplant recipients 65 years and older.Methods: Between 1/2009 and 12/2014, 687 patients underwent a kidney…
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