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Articles tagged "Graft failure"

  • 2018 American Transplant Congress

    Urinary C5b-9 is an Independent Predictor of Graft Failure in Renal Transplant Recipients

    R. Lammerts, M. Eisenga, M. Alyami, M. Seelen, M. Daha, J. van den Born, S. Bakker, S. Berger, On behalf of the COMBAT Comsortium.

    Department of Nephrology, University Medical Centre Groningen, Groningen, Netherlands.

    IntroductionChronic antibody-mediated rejection is thought to be the main cause of late kidney-allograft loss, involving donor-specific antibody–mediated activation of the complement system. Activation of filtered…
  • 2018 American Transplant Congress

    Incidence Trends among Deceased Liver Transplant Recipients in the United States, 2011-2016: A Propensity Score-Matched Study

    R. Schilke, M. Safwan, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai.

    Transplant Institute, Henry Ford Hospital, Detroit, MI.

    BackgroundDonation after cardiac death (DCD) donor liver graft is a known risk factor for graft failure secondary to primary non-function (PNF) and/or diffuse cholangiopathy (DC).…
  • 2018 American Transplant Congress

    Graft Failure in Recurrent IgA Nephropathy Following Living Kidney Transplantation: Predictive Factors Analysis of 102 Biopsies

    J. Zhang, J. Qiu, G. Chen, C. Wang, L. Chen.

    Organ Transplant Unit, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aim To investigate the predictive factors related to graft failure in recurrentIgA nephropathy (IgAN) following living kidney transplantation. Methods We identified a series of 102…
  • 2018 American Transplant Congress

    Urine Pellet Podocyte mRNAs Correlate Closely with Late Kidney Allograft Loss-of-Function

    A. Naik,1 J. Aqeel,1 D. Cibrik,2 M. Samaniego,1 M. Chowdhury,1 S. Wang,1 F. Afshinnia,1 R. Wiggins.1

    1Univ Michigan, Ann Arbor; 2Univ Kansas, Kansas City.

    10-year surveillance biopsy studies (Nankivell,2003 & Stegall,2017) and podometric studies are compatible with progressive glomerulosclerosis (GS) contributing to long-term allograft loss-of-function.Thus one would expect to…
  • 2018 American Transplant Congress

    Genome Wide Non-HLA Alloimmunity Contributes to Graft Loss after Kidney Transplantation

    R. Reindl-Schwaighofer, A. Heinzel, A. Kainz, K. Jelencsics, O. Viklicky, G. Böhmig, G. Fischer, B. Keating, R. Oberbauer.

    Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; Transplant Institute, University of Pennsylvania, Philadelphia, PA.

    BackgroundChronic rejection is the main cause of renal transplant loss after the first year and has mostly been attributed to alloimmune responses against human leukocyte…
  • 2018 American Transplant Congress

    Transplant Outcomes in Female African American Recipients

    A. Patel,1 R. Prashar,1 D. Lim.2

    1Transplant Nephrology, Henry Ford Transplant Institute, Detroit, MI; 2School of Medicine, Wayne State University, Detroit, MI.

    We are aware of the multifactorial healthcare disparity affecting African American (AA) population with regards to renal transplantation. Little is known about AA female renal…
  • 2018 American Transplant Congress

    Pediatric Kidney Allograft Outcomes Following Identification of Transplant Glomerulopathy by Electron Microscopy

    J. Grodsky, R. Craver, I. Ashoor.

    LSU Health Sciences Center, New Orleans, LA.

    We have previously shown that electron microscopy (EM) can facilitate early diagnosis of transplant glomerulopathy (TG) in pediatric kidney transplant biopsies (Bx) with normal light…
  • 2018 American Transplant Congress

    Etiologies and Long-Term Outcomes of Acute Kidney Injury in Older Kidney Transplant Recipients

    R. Rodriguez, P. Amechi, V. Rao, D. Taber, M. Posadas Salas.

    Medical University of South Carolina, Charleston, SC.

    Older kidney transplant recipients face challenges of post-transplant complications related to frailty and comorbidity burden. They are particularly vulnerable to acute kidney injury (AKI) due…
  • 2018 American Transplant Congress

    Landscape of Living Donor Kidney Transplantation with International Donors in the United States

    A. Thomas,1 M. Henderson,1 A. Shaffer,1 A. Massie,1 B. Koons,2 K. Lentine,3 D. Segev,1 F. Al Ammary.1

    1JHU, Baltimore; 2Villanova University, Villanova; 3SLU, St. Louis.

    International living kidney donors (LKDs) can donate to candidates listed in the US. Recently, concerns were raised that international LKD organ-recipients might not achieve the…
  • 2018 American Transplant Congress

    Presence of Donor Specific Antibodies is Associated with Accelerated Podocyte Detachment

    A. Naik, J. Aqeel, D. Cibrik, M. Samaniego, S. Wang, M. Chowdhury, F. Afshinnia, R. Wiggins.

    University of Michigan, Ann Arbor; University of Kansas, Kansas City.

    Introduction: Both indication and 10-yr surveillance biopsy data point to the important role of progressive glomerular disease in intermediate and long-term allograft outcomes. As all…
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