Articles tagged "Graft failure"

2019 American Transplant Congress
Biomarker Candidate Discovery for Kidney Allograft Monitoring via Urinary Exosome Proteome Analysis
J. Kim¹, Y. Wee¹, M. Choi¹, H. Jung¹, J. Choi¹, H. Kwon¹, J. Jung¹, Y. Ko¹, D. Kim¹, K. Kim², Y. Cho³, H. Go³, Y. Kim¹, D. Han¹, S. Shin¹
¹Department of Surgery, Asan Medical Center, Seoul, Korea, Republic of, ²Department of Convergence Medicine, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea, Republic of, ³Department of Pathology, Asan Medical Center, Seoul, Korea, Republic of
*Purpose: There is a need for the development of noninvasive molecular biomarkers with high reliability and predictive power for early diagnosis and monitoring of any…
2019 American Transplant Congress
Urine Uromodulin Associates with Deceased Donor Acute Kidney Injury and Allograft Failure
S. G. Mansour¹, I. Hall², P. Reese³, T. Ashkar⁴, Y. Jia⁴, H. Thiessen-Philbrook⁴, M. Doshi⁵, C. R. Parikh⁴
¹Yale, New Haven, CT, ²University of Utah, Salt Lake City, UT, ³Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁴Johns Hopkins University, Baltimore, MD, ⁵University of Michigan, Ann Arbor, MI
*Purpose: Produced exclusively by renal epithelial cells of the thick ascending limb, Uromodulin (UMOD, also known as Tamm-Horsfall protein) is the major component of hyaline…
2019 American Transplant Congress
Nodular Regenerative Hyperplasia after Liver Transplant – It is All in the Presentation
A. K. Chen¹, S. Yamaguchi², C. Praglin², E. Agudelo², F. K. Yao², S. M. Syed², G. R. Roll²
¹University of California, San Francisco - Fresno, Fresno, CA, ²University of California, San Francisco, San Francisco, CA
*Purpose: There is a paucity of data on nodular regenerative hyperplasia (NRH) after liver transplant (LT). We report the largest existing case series with extensive…
2019 American Transplant Congress
Effects of Co-Morbidities on Kidney Transplantation Outcome in South Korea: A Nationwide-Population Based Study
M. Yu¹, S. Park², J. Moon², J. Jeong², J. Kim², Y. Kim², K. Han³, Y. Kim², H. Lee²
¹Hanyang University Guri Hospital, Guri, Korea, Republic of, ²Seoul National University Hospital, Seoul, Korea, Republic of, ³College of Medicine, Catholic University, Seoul, Korea, Republic of
*Purpose: Kidney transplantation (KT) has become the most effective treatment for end stage renal disease. Improvement of general medical care as well as immunosuppressive agents…
2019 American Transplant Congress
Patterns of Emergency Department (ED) Utilization between Transplant and Non-Transplant Centers and Impact on Clinical Outcomes in Kidney Recipients
H. Perkins, N. Patel, V. Rohan, Z. Su, D. DuBay, J. McGillicuddy, D. Taber
MUSC, Charleston, SC
*Purpose: There is a high rate of ED utilization in kidney recipients post-transplant (txp); ED visits are associated with readmission rates and lower 3-yr survival…
2019 American Transplant Congress
Not All Donor-Specific Antibodies Are Equal: Predictors of Risk of Chronic Lung Allograft Dysfunction
C. J. Iasella¹, C. R. Ensor², M. Marrari³, M. Mangiola³, C. A. Moore¹, M. R. Morrell⁴, J. Pilewski⁴, J. F. McDyer⁴, A. Zeevi³
¹Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA, ²Florida Hospital Transplant Institute, AdventHealth Orlando, Orlando, FL, ³Pathology, University of Pittsburgh, Pittsburgh, PA, ⁴Medicine, University of Pittsburgh, Pittsburgh, PA
*Purpose: Donor-specific HLA antibodies (DSA) have been previously associated with chronic lung allograft dysfunction (CLAD). However, the DSA characteristics that predict risk of CLAD are…
2019 American Transplant Congress
Predicting Allograft Outcomes of Renal Transplantation with Pretransplant Metrics
J. Tchervenkov¹, M. Nguyen², S. Negi¹, S. Paraskevas¹
¹RIMUHC, Montreal, QC, Canada, ²SSM Health Saint Louis University Hospital, St. Louis, MO
*Purpose: Early allograft dysfunction as well as long-term graft loss are major obstacles to successful kidney transplantation. Currently, kidney donor risk index (KDRI) is used…
2019 American Transplant Congress
Risk Factors for Post-Transplant Outcomes in Living and Deceased Donor Liver Transplantation. An Analysis of UNOS Registry
T. Kitajima, S. Nagai, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud
Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: The Model for End-Stage Liver Disease (MELD) score has been used for predicting waitlist outcomes in patients with cirrhosis. However, the post-transplant prognostic value…
2019 American Transplant Congress
The Association of Estimated Glomerular Filtration Rate at One Year Post-Kidney Transplant with Graft Loss is Not Modified by Delayed Graft Function
J. Gill, M. Kadatz, J. Gill
University of British Columbia, Vancouver, BC, Canada
*Purpose: In kidney transplant recipients, eGFR at 1 year post-transplant has been shown to be associated with graft loss, but it is unclear if this…
2019 American Transplant Congress
Early Allograft Dysfunction in the Setting of Histologic Ischemia Reperfusion Injury Following Liver Transplantation: Analysis of Predictors and Outcomes
T. Ito, J. Aziz, V. G. Agopian, S. Younan, J. DiNorcia, H. Yersiz, D. G. Farmer, R. W. Busuttil, F. M. Kaldas
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Hepatic ischemia-reperfusion injury (IRI) in Liver Transplantation (LT) is believed to contribute to Early Allograft Dysfunction (EAD). However, the relationship between IRI and EAD…