Articles tagged "Graft failure"

2019 American Transplant Congress
Utility of a Novel dd-cfDNA Test to Detect Injury in Renal Post-Transplant Patients
J. Peabody¹, P. Billings², Z. Demko², D. Paculdo¹, M. Tran¹, S. Moshkevich², C. Valdenor¹
¹QURE Healthcare, San Francisco, CA, ²Natera, Inc., San Carlos, CA
*Purpose: Detecting allograft injury and rejection is critical to preventing graft loss. Current standard of care (SoC) relies on serum creatinine (SC) and biopsy to…
2019 American Transplant Congress
Biomarkers in Multivisceral and Intestinal Transplantation
D. A. Cheung¹, J. Garcia¹, T. Beduschi², A. H. Langshaw¹, K. L. Arheart³, I. A. Gonzalez⁴
¹Pediatric Gastroenterology, University of Miami, Miami, FL, ²Surgery, Division of Liver/GI Transplant, University of Miami, Miami, FL, ³Public Health Sciences, Division of Biostatistics, University of Miami, Miami, FL, ⁴Pediatric Infectious Diseases and Immunology, University of Miami, Miami, FL
*Purpose: Multivisceral transplant (MVT) and isolated intestinal transplant (ITx) are complex surgical procedures that result in a pro-inflammatory state, making interpretation of biomarkers in the…
2019 American Transplant Congress
Humoral Immune Responses to Kidney Associated Non-HLA Antigens is Not Associated with Progression to Chronic Immune Injury in Kidney Transplant Recipients
S. Sukumaran Nair¹, R. Ravichandran², R. Heilman¹, A. Jaramillo¹, D. Ramon¹, M. Buras¹, B. Kaplan¹, T. Mohanakumar²
¹Mayo Clinic, Phoenix, AZ, ²St. Joseph’s Hospital, Phoenix, AZ
*Purpose: Development of donor specific anti-HLA (DSA) although is a known risk factor for Chronic immune injury (CII), it is undetectable in many patients with…
2019 American Transplant Congress
Association Of Kdpi And Dgf With Dcd Kidney Transplants Outcomes
M. Sampaio, B. Abdalla, S. Bunnapradist
David Geffen Sch of Med at UCLA, Los Angeles, CA
*Purpose: Donors of circulatory death (DCD) have similar outcomes compared to donors of brain death (DBD) in kidney transplants. It is unclear if this is…
2019 American Transplant Congress
Association between Recipient Sex and Risk of Heart Graft Failure
A. Chackowicz¹, X. Zhang², M. Dahhou², R. Sapir-Pichhadze³, H. Cardinal⁴, B. Foster⁵
¹Faculty of Medicine, McGill University, Montreal, QC, Canada, ²Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³Dept. of Medicine, McGill University, Montreal, QC, Canada, ⁴Dept. of Medicine, Université de Montréal, Montreal, QC, Canada, ⁵Dept. of Pediatrics, McGill University, Montreal, QC, Canada
*Purpose: Previous studies of sex differences in heart transplant outcomes focused on interactions between donor and recipient sex, but did not consider the potentially modifying…
2019 American Transplant Congress
Clinical Features of IgA Nephropathy Recurrence after Kidney Transplantation
H. HIGUCHI¹, K. Hotta², H. Harada¹, Y. Wada¹, A. Mitsuke¹, D. Iwami², N. Shinohara²
¹Urology and Kidney transplant surgery, Sapporo General Hospital, Sapporo, Japan, ²Urology, Hokkaido University, Sapporo, Japan
*Purpose: Recurrence of IgA nephropathy (IgAN) is one of the major cause of kidney graft loss. The clinical features of disease recurrence after kidney transplantation…
2019 American Transplant Congress
Atypical Hemolytic Uremic Syndrome Concomitant Complement Factor H Gene Variations Leading to Early Renal Allograft Loss: Multicenter Cases Report from China
J. Wen¹, Z. Jin², N. Gong³, X. Xu⁴
¹Jinling Hospital, Nanjing, Jiangsu, China, ²Department of Renal Transplantation, The First Affiliated Hospital of Medical College,Xi’an Jiaotong University, Xi 'an, China, ³Organ Transplantation, Organ Transplantation Key Laboratory of the Ministry of Education, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ⁴The First Hospital Affiliated to Army Medical University, Beijing, China
*Purpose: The ratio of early renal allograft loss caused by hyperacute rejection, severe surgical complications and sever infection decreased gradually during recent years. Atypical hemolytic…
2019 American Transplant Congress
Indicators of Impending Pig Organ Xenograft Failure: Relevance to Clinical Xenotransplantation
H. Iwase¹, A. Jagdale¹, T. Yamamoto¹, G. Zhang¹, Q. Li¹, J. Foote¹, D. Ayares², H. Hara¹, D. K. Cooper¹
¹University of Alabama at Birmingham, Birmingham, AL, ²Revivicor, Inc., Blacksburg, VA
*Purpose: In pig-to-baboon organ xenotransplantation, coagulation dysfunction and inflammation have been suggested to be associated with acute humoral xenograft rejection. We have evaluated platelet counts,…
2019 American Transplant Congress
The Impact of Extra-Anatomical Hepatic Artery Reconstruction during Living Donor Transplantation on Biliary Complications and Graft and Patient Survival
Y. Chung, J. Kim, S. Kim, J. Rhu, S. Lee, K. Lee, S. Lee, G. Choi, J. Park, S. Kim, J. Joh, S. Lee
Transplantation, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: This study was designed to analyze the feasibility of extra-anatomical hepatic artery reconstruction in living donor liver transplantation.*Methods: Patients who underwent their first living…
2019 American Transplant Congress
Non-Immunologic Donor-Recipient Pairing, HLA Matching, and Graft Loss in Deceased Donor Kidney Transplantation
A. Vinson¹, B. Kiberd¹, R. Davis², K. Tennankore¹
¹Dalhousie University, Halifax, NS, Canada, ²Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
*Purpose: In kidney transplantation, non-immunologic donor-recipient (D-R) pairing is generally not given the same consideration as immunologic matching. The aim of this study was to…