Articles tagged "Graft failure"

2020 American Transplant Congress
Center Performance for Liver Retransplantation Candidates is More Heterogeneous Than for Initial Liver Transplantation Recipients
T. Bittermann, P. L. Abt, D. E. Schaubel
University of Pennsylvania, Philadelphia, PA
*Purpose: This study evaluated center performance for wait-list outcomes for adult candidates awaiting liver retransplantation (reLT), and its association with initial liver transplant (iLT) center…
2020 American Transplant Congress
Do Higher Remuzzi Scores Make Good Kidneys Bad? Examining Histologic Criteria within the Framework of Single Kidney Transplantation
V. Fleetwood¹, C. Kensinger², C. Papageorge¹, D. Aufhauser¹, P. Pasha¹, G. Leverson³, B. Welch¹, D. Foley¹
¹Department of Transplantation, University of Wisconsin, Madison, WI, ²Department of Transplantation, Piedmont Transplant Center, Atlanta, GA, ³Department of Statistics, University of Wisconsin, Madison, WI
*Purpose: The Remuzzi score (RS), a histologic tool to assess chronic allograft damage, can guide allocation to single (SKT) or dual (DKT) kidney implantation. RS…
2020 American Transplant Congress
Risk of Histological Relapse in Patients with Monoclonal Gammopathy of Renal Significance after Kidney Transplantation
A. Bentall¹, C. Heybeli², F. G. Cosio¹, M. El Ters¹, N. Leung¹, M. P. Alexander³
¹Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ²Department of Internal Medicine, Dokuz Eylul University, Izmir, Turkey, ³Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
*Purpose: There is increased recognition of Monoclonal Gammopathy of Renal Significance (MGRS) but data on kidney transplant (ktx)outcomes are lacking. We assessed KTX outcomes of…
2020 American Transplant Congress
Incidence and Risks Factors of Kidney Allograft Loss Due to BK Virus: UNOS Data Set
H. Patel¹, K. Agrawal¹, A. Pawar¹, N. Leeaphorn², F. Cardarelli¹, N. Agrawal¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Transplant Nephrology, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO
*Purpose: BK virus infection can lead to graft dysfunction and loss in kidney transplant patients. Incidence and prevalence of BK Viremia (BKV) and BK Virus…
2019 American Transplant Congress
Humoral Immune Responses to Kidney Associated Non-HLA Antigens is Not Associated with Progression to Chronic Immune Injury in Kidney Transplant Recipients
S. Sukumaran Nair¹, R. Ravichandran², R. Heilman¹, A. Jaramillo¹, D. Ramon¹, M. Buras¹, B. Kaplan¹, T. Mohanakumar²
¹Mayo Clinic, Phoenix, AZ, ²St. Joseph’s Hospital, Phoenix, AZ
*Purpose: Development of donor specific anti-HLA (DSA) although is a known risk factor for Chronic immune injury (CII), it is undetectable in many patients with…
2019 American Transplant Congress
Association Of Kdpi And Dgf With Dcd Kidney Transplants Outcomes
M. Sampaio, B. Abdalla, S. Bunnapradist
David Geffen Sch of Med at UCLA, Los Angeles, CA
*Purpose: Donors of circulatory death (DCD) have similar outcomes compared to donors of brain death (DBD) in kidney transplants. It is unclear if this is…
2019 American Transplant Congress
Post-Transplant Lymphopenia is Associated with Higher Risk of Graft Failure, Death and Viral Infections
A. Dujardin¹, M. Lorent², C. Kerleau¹, S. Brouard³, M. Giral¹
¹Nephrology, Nantes University Hospital, Nantes, France, ²UMR_S 1246, INSERM, Nantes, France, ³CRTI UMR 1064, Inserm, Nantes, France
*Purpose: The transplantation field needs biomarkers to assess the level of immunosuppression. In this study, we aimed to analyze the independent correlation between the number…
2019 American Transplant Congress
The Study on the DNA Methylation Dynamic Changes after Renal Transplantation
C. Zhu, H. Jiang, J. Chen
Nephrology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China
*Purpose: Kidney transplantation is the most effective therapeutic regimen for most ESRD patients. However, graft dysfunction remains to be a major challenge. DNA methylation is…
2019 American Transplant Congress
Utility of a Novel dd-cfDNA Test to Detect Injury in Renal Post-Transplant Patients
J. Peabody¹, P. Billings², Z. Demko², D. Paculdo¹, M. Tran¹, S. Moshkevich², C. Valdenor¹
¹QURE Healthcare, San Francisco, CA, ²Natera, Inc., San Carlos, CA
*Purpose: Detecting allograft injury and rejection is critical to preventing graft loss. Current standard of care (SoC) relies on serum creatinine (SC) and biopsy to…
2019 American Transplant Congress
Biomarkers in Multivisceral and Intestinal Transplantation
D. A. Cheung¹, J. Garcia¹, T. Beduschi², A. H. Langshaw¹, K. L. Arheart³, I. A. Gonzalez⁴
¹Pediatric Gastroenterology, University of Miami, Miami, FL, ²Surgery, Division of Liver/GI Transplant, University of Miami, Miami, FL, ³Public Health Sciences, Division of Biostatistics, University of Miami, Miami, FL, ⁴Pediatric Infectious Diseases and Immunology, University of Miami, Miami, FL
*Purpose: Multivisceral transplant (MVT) and isolated intestinal transplant (ITx) are complex surgical procedures that result in a pro-inflammatory state, making interpretation of biomarkers in the…