Articles tagged "Graft failure"

2020 American Transplant Congress
Incidence and Risks Factors of Kidney Allograft Loss Due to BK Virus in Pediatric Population: UNOS Data Set
H. Patel¹, K. Agrawal¹, A. Pawar¹, N. Rodig², N. Agrawal¹, F. Cardarelli¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Nephrology (Medicine), Boston Children's Hospital, Boston, MA
*Purpose: BK virus infection can lead to graft dysfunction and loss in kidney transplant patients. Incidence and prevalence of BK Viremia (BKV) and BK Virus…
2020 American Transplant Congress
Establishment of Spontaneous Tolerance of Kidney Allografts is Dependent on Mitigation of Ischemia-Reperfusion Injury via the BLTA-HVEM Pathway
Q. Yuan¹, S. Hong¹, E. Szuter¹, Y. Zhao¹, E. Acheampong¹, I. Rosales¹, M. Kronenberg², P. Russell¹, J. Madsen¹, R. Colvin¹, A. Alessandrini¹
¹Massachusetts General Hospital, Boston, MA, ²La Jolla Institute for Allergy & Immunology, La Jolla, CA
*Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) develop tolerance while other combinations do not (e.g. B6 to DBA/2). We…
2020 American Transplant Congress
Long-Term Kidney Graft Survival is Superior with Simultaneous-Liver Kidney (SLK) Transplants Than Kidney Alone (KA) or Kidney after Liver (KALi) Transplants in the United States
N. Lim¹, S. M. Riad¹, S. Jackson², J. Lake¹
¹University of Minnesota, Minneapolis, MN, ²M Health Fairview, Minneapolis, MN
*Purpose: There is a concern that SLK transplant recipients have worse outcomes resulting in poor utilization of the kidney donor pool. We utilized the Scientific…
2020 American Transplant Congress
Low Mycophenolic Acid Levels are Associated with More Inflammation on 1 Year Protocol Biopsies and Lower Graft Survival in Kidney Transplant Recipients
J. Huskey, G. Mour, M. Ryan, S. Nair, M. Smith, R. Heilman
Mayo Clinic Arizona, Phoenix, AZ
*Purpose: Data is limited on the association of Mycophenolic Acid (MPA) concentration on protocol kidney transplant biopsies. Our aim is to compare clinical outcomes and…
2019 American Transplant Congress
Poor Outcomes in Kidney Transplant Candidates & Recipients with History of Falls
N. Chu¹, H. Ying¹, Z. Shi¹, C. Haugen¹, S. Norman², D. Segev¹, M. McAdams-DeMarco¹
¹Johns Hopkins, Baltimore, MD, ²Michigan Medical Center, Ann Arbor, MI
*Purpose: In patients with ESRD, serious fall injuries (e.g. fractures) are associated with decreased chance of listing or transplantation. It is likely that KT candidates…
2019 American Transplant Congress
Outcomes after Simultaneous Kidney Pancreas versus Pancreas after Kidney Transplantation
S. Parajuli, A. Arunachalam, K. Swanson, F. Aziz, N. Garg, R. Redfield, D. Kaufman, A. Djamali, J. Odorico, D. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: Simultaneous pancreas and kidney (SPK) or pancreas after kidney (PAK) transplant are potential options for diabetic ESRD patients. Historically, PAK pancreas graft outcomes were…
2019 American Transplant Congress
Lack of Response to Tocilizumab in Kidney Transplants with Chronic Antibody-Mediated Rejection
D. Kumar¹, F. Safavi¹, R. Sandhu¹, P. Halloran², I. Yakubu¹, M. Levy¹, I. Moinuddin¹, P. Kimball¹, L. Kamal¹, A. King¹, H. Massey¹, G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada
*Purpose: Chronic antibody mediated rejection (cAbMR) is a major cause of long-term kidney transplant (KT) loss. Traditional therapies for cAbMR have unclear efficacy with significant…
2019 American Transplant Congress
Alteration in Local Complement Activation in First 24h Post-Lung Transplantation (LTx) Helps Identify Recipients Developing Primary Graft Dysfunction
H. Kulkarni¹, M. Elvington², L. Ma¹, M. Cano¹, K. Pugh³, R. Hachem¹, J. Atkinson², A. Gelman³
¹Pulmonary and Critical Care Medicine, Washington University, Saint Louis, MO, ²Rheumatology, Washington University, Saint Louis, MO, ³Surgery, Washington University, Saint Louis, MO
*Purpose: Primary graft dysfunction (PGD) is a form of acute lung injury driven by ischemia-reperfusion mediated damage. An increase in plasma complement proteins - specifically…
2019 American Transplant Congress
Impact of Delayed Graft Function on Allograft Survival in DCD versus DBD Kidneys
T. Ishaque, A. B. Massie, J. Ruck, C. Holscher, J. G. Wang, D. L. Segev
Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Several single-center studies have suggested no link between delayed graft function (DGF) and graft survival in recipients of donation after cardiac death (DCD) kidneys,…
2019 American Transplant Congress
Early Pancreas Loss in Simultaneous Pancreas Kidney Transplants: Does It Matter for the Kidney?
D. Das, J. Huskey, R. Heilman, K. S. Reddy, A. Moss, J. Harbell, C. Jadlowiec
Mayo Clinic AZ, Phoenix, AZ
*Purpose: Surgical and immunosuppressive refinements have led to improved outcomes in simultaneous pancreas-kidney (SPK) transplants. Despite these improvements, early pancreas allograft loss remains not insignificant.…