Articles tagged "Graft failure"

2020 American Transplant Congress
Hepatic Artery Thrombosis in the Modern Era of Increased Utilization of Livers from Older Donors
A. Kernodle, M. Krach, P. Chiang, D. Segev, A. Massie, J. Garonzik-Wang
Johns Hopkins Hospital, Baltimore, MD
*Purpose: In a prior study using national registry data, deceased donor age greater than 50 was associated with a 35% to 61% increased risk of…
2020 American Transplant Congress
Kidney Transplantation in Inherited Kidney Diseases
Y. Caliskan¹, H. Yazici², R. Ouseph¹, Y. Ozluk³, H. Randall⁴, E. Demir², F. Savran Oguz⁵, A. Turkmen², M. S. Sever², K. Lentine¹
¹Division of Nephrology, Saint Louis University, Saint Louis, MO, ²Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, ⁵Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey
*Purpose: We aimed to evaluate the kidney transplant (KTx) recipients with inherited kidney diseases and investigate the causal genetic variants in recipients with undetermined etiology.*Methods:…
2020 American Transplant Congress
What Are the Peri-Operative and Longterm Outcomes of Utilizing Donation after Circulatory Death Livers with Macrosteatosis? A Multicenter Analysis
K. Croome¹, A. Mathur², S. Mao¹, B. Aqel³, P. Senada¹, J. Piatt¹, J. Heimbach⁴, A. Moss³, C. Rosen⁴, C. Taner¹
¹Mayo Clinic Jacksonville, Jacksonville, FL, ²Mayo Clinic Arizona, Scotsdale, AZ, ³Mayo Clinic Arizona, Scottsdale, AZ, ⁴Mayo Clinic Rochester, Rochester, MN
*Purpose: Given the potentially additive risk from using donor livers that are both steatotic and from a donation after circulatory death(DCD) donor, there is a…
2020 American Transplant Congress
Decoding the Troubled Allograft: Proteinuria within the 1^st Post-Transplant Year Associates with and Risk Stratifies Inflamed Renal Transplants
A. Cherukuri, R. Mehta, A. Tevar, R. Munjal, K. Kalra, C. Puttarajappa, P. Sood, C. Wu, S. Hariharan
Starzl Transplantation Institute, UPMC, Pittsburgh, PA
*Purpose: The relationship between progression of proteinuria and allograft histology through the 1st year with clinical outcomes is unclear.*Methods: Here, we systematically studied proteinuria {early…
2020 American Transplant Congress
Development of a Transplant Financial Aid Tool Kit
C. Rogers¹, K. Minghella¹, K. Sullivan¹, J. Ryan¹, E. Keegan-Pits¹, M. Cote¹, S. Shao¹, K. Joyal¹, R. Youn², N. Elias¹
¹Massachusetts General Hospital Transplant Center, Boston, MA, ²Community, A Walgreens Pharmacy, Boston, MA
*Purpose: Medication access is an essential element to post transplant medication adherence. Access to medications can often be hindered by high copays, insurance premiums, changes…
2020 American Transplant Congress
Multifaceted Roles of Follicular T Cell Subsets in Controlling Antibody Mediated Rejection
M. T. Mohammed
Renal- Transplant Research Center, Brigham and Women's Hospital- Harvard Medical School, Boston, MA
*Purpose: Assess the roles of T Follicular Helper and Regulatory cells in controlling pathogenic donor-specific antibodies (DSA) and antibody-mediated rejection(AbMR) during kidney transplantation.*Methods: Here we…
2020 American Transplant Congress
Effectiveness and Tolerability of Cidofovir for the Management of BK Viremia in Kidney Transplant Recipients
M. Thornberg¹, J. Hedvat¹, N. Lange¹, C. Brennan², D. Salerno¹, D. Tsapepas²
¹NewYork-Presbyterian Hospital, Department of Pharmacy, New York, NY, ²Columbia Irving University Medical Center, Department of Transplant Surgery, New York, NY
*Purpose: BK viremia (BKV) is a common complication after kidney transplantation (KT) that often leads to graft dysfunction and loss. Without consensus management guidelines and…
2020 American Transplant Congress
Marginal Zone B Cells Support Donor-Specific Alloantibody Responses to Heart Allografts
V. Gorbacheva, R. Fan, W. Baldwin, R. Fairchild, A. Valujskikh
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Production of high affinity isotype-switched donor specific alloantibodies (DSA) after transplantation is associated with germinal center formation by follicular (FO) B cells whereas the…
2020 American Transplant Congress
Artificial Intelligence May Detect Donor Liver Steatosis and Predict Early Post-Transplantation Graft Failure
R. R. Narayan, L. Yang, N. Abadilla, S. B. Chen, J. P. Higgins, M. L. Melcher
Stanford University, Stanford, CA
*Purpose: To compare the accuracy of donor liver biopsy slides scored by manual histopathologic review versus a computer vision artificial intelligence (CVAI) platform to predict…
2020 American Transplant Congress
Early Corticosteroid Withdrawal in Pancreas and Simultaneous Pancreas-Kidney Transplant Recipients: Long-Term Clinical and Metabolic Outcomes of from a Single Center Retrospective Cohort
A. Lichvar, L. Lin, Y. Chen, Y. Yen, D. Pierce, A. Nadeem, P. West-Thielke, I. Tang, J. Almario, M. Spaggiari, I. Tzvetanov, E. Benedetti, M. Campara
University of Illinois at Chicago, Chicago, IL
*Purpose: Tacrolimus, mycophenolate mofetil, and chronic corticosteroids (CCS) are the most popular immunosuppression regimen after pancreas transplantation. Early corticosteroid withdrawal (ECSWD) is an increasingly popular…