Articles tagged "Graft failure"

2020 American Transplant Congress
Incidence and Risks Factors of Kidney Allograft Loss Due to BK Virus in Pediatric Population: UNOS Data Set
H. Patel¹, K. Agrawal¹, A. Pawar¹, N. Rodig², N. Agrawal¹, F. Cardarelli¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Nephrology (Medicine), Boston Children's Hospital, Boston, MA
*Purpose: BK virus infection can lead to graft dysfunction and loss in kidney transplant patients. Incidence and prevalence of BK Viremia (BKV) and BK Virus…
2020 American Transplant Congress
Establishment of Spontaneous Tolerance of Kidney Allografts is Dependent on Mitigation of Ischemia-Reperfusion Injury via the BLTA-HVEM Pathway
Q. Yuan¹, S. Hong¹, E. Szuter¹, Y. Zhao¹, E. Acheampong¹, I. Rosales¹, M. Kronenberg², P. Russell¹, J. Madsen¹, R. Colvin¹, A. Alessandrini¹
¹Massachusetts General Hospital, Boston, MA, ²La Jolla Institute for Allergy & Immunology, La Jolla, CA
*Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) develop tolerance while other combinations do not (e.g. B6 to DBA/2). We…
2020 American Transplant Congress
Long-Term Kidney Graft Survival is Superior with Simultaneous-Liver Kidney (SLK) Transplants Than Kidney Alone (KA) or Kidney after Liver (KALi) Transplants in the United States
N. Lim¹, S. M. Riad¹, S. Jackson², J. Lake¹
¹University of Minnesota, Minneapolis, MN, ²M Health Fairview, Minneapolis, MN
*Purpose: There is a concern that SLK transplant recipients have worse outcomes resulting in poor utilization of the kidney donor pool. We utilized the Scientific…
2020 American Transplant Congress
Low Mycophenolic Acid Levels are Associated with More Inflammation on 1 Year Protocol Biopsies and Lower Graft Survival in Kidney Transplant Recipients
J. Huskey, G. Mour, M. Ryan, S. Nair, M. Smith, R. Heilman
Mayo Clinic Arizona, Phoenix, AZ
*Purpose: Data is limited on the association of Mycophenolic Acid (MPA) concentration on protocol kidney transplant biopsies. Our aim is to compare clinical outcomes and…
2020 American Transplant Congress
Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation
H. Hirao¹, T. Ito¹, K. Nakamura², S. Kageyama¹, K. Kadono¹, H. Kojima¹, K. J. Dery¹, S. Younan¹, R. W. Busuttil¹, F. M. Kaldas¹, J. W. Kupiec‐Weglinski¹
¹UCLA, Los Angeles, CA, ²Kyoto University, Kyoto, Japan
*Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
2020 American Transplant Congress
Renal Allograft Outcome from Hypertensive Donor: Comparison between Living and Deceased Donor
H. Hwang¹, J. Kong¹, J. Kim¹, Y. Kim¹, J. Moon¹, K. Jeong¹, S. Song², S. Song³, H. Shin⁴, J. Yang⁵, C. Ahn⁶, Y. Lee⁷, S. Lee¹
¹Division of Nephrology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ²Pusan National University Hospital, Pusan, Korea, Republic of, ³Ewha Womans University Medical Center, Seoul, Korea, Republic of, ⁴Kosin University College of Medicine, Pusan, Korea, Republic of, ⁵Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ⁶Department of Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of, ⁷Division of Nephrology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seoul, Korea, Republic of
*Purpose: Donor shortage is a serious problem in renal transplantation, and hypertensive living donor is potential candidates to expand donor pool. However, it is not…
2020 American Transplant Congress
Comparative Analysis of Patient Outcomes between Urology-Led versus General Surgery-Led Kidney Transplant Centers
A. Mishra¹, A. Cohen¹, N. Koizumi², A. Ortiz³, K. Pai¹, B. Bullock¹, S. Sureddi¹, J. Ortiz¹
¹The University of Toledo College of Medicine and Life Sciences, Toledo, OH, ²George Mason University, Arlington, VA, ³Albany Medical College, Albany, NY
*Purpose: To assess renal patient outcomes between kidney transplant centers across the United States based on whether their surgical leader was initially trained via the…
2020 American Transplant Congress
Calcium Oxalate Deposition in Kidney Allografts: Clinical Chracteristics and Outcome
S. Sritharan¹, J. Kamal², S. A. Husain¹, I. Batal¹, J. Chang¹
¹Columbia University Irving Medical Center, New York, NY, ²University of Virginia, Charlottesville, VA
*Purpose: To better understand its clinical significance and prognostic value, we investigated the clinical characteristics and outcomes of patients with calcium oxalate deposition in kidney…
2020 American Transplant Congress
Allograft Loss and Patient Death among Kidney Transplant Recipients; Is Therapy Non-Adherence the Underlying Perpetrator?
K. Kalra, R. Munjal, A. Cherukuri, R. Mehta, C. Puttarajappa, D. Jorgensen, P. Sood, C. Wu, N. Shah, S. Hariharan
Nephrology, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: To ascertain causes of allograft dysfunction, loss and death in a cohort of kidney transplant patients*Methods: In this Retrospective cohort study, 943 patients who…
2020 American Transplant Congress
Ranking Eplet Mismatches as Predictors of Graft Failure
W. Zhang¹, H. Mohammadhassanzadeh¹, K. Oualkacha², H. Gebel³, W. Klement⁴, R. Sapir-Pichhadze¹
¹McGill University, Montreal, QC, Canada, ²UQAM, Montreal, QC, Canada, ³Emory University Hospital, Atlanta, GA, ⁴Canadian Blood Services, Ottawa, ON, Canada
*Purpose: Donor:recipient matching at the level of sequence defined HLA targets (eplets) is being promoted as a biologically sound strategy to prevent graft failure. Because…