ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2020 American Transplant Congress

    Impact of Chronic Changes on Preimplantation Biopsy (PBx) on Outcomes after Deceased Donor Kidney Transplantation (DDKTx)

    J. Ninan, R. Heilman, M. Smith, J. Harbell, S. S. Nair, C. Jadloweic, H. Khamash, A. Moss, K. S. Reddy

    Mayo Clinic, Phoenix, AZ

    *Purpose: The value of PBx is unclear. The aim of this study was to determine the prognostic value of chronic changes on PBx on graft…
  • 2020 American Transplant Congress

    Late Intra-Patient Tacrolimus Variability Predicts De Novo Donor-Specific Antibody and Graft Loss

    J. Lee1, E. Kim1, S. Yang2, S. Kim1, H. Choi3, B. Kim4, M. Ju5, M. Kim2, S. Kim2, Y. Kim2, K. Huh2

    1Department of Transplantation Surgery, Severance Hospital, Seoul, Korea, Republic of, 2Department of Transplantation Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 3Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 4Department of Internal Medicine, Severance Hospital, Seoul, Korea, Republic of, 5Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Intra-patient variability (IPV) of tacrolimus level has been associated with poor outcomes after kidney transplantation. However, these findings were limited mainly to measurements early…
  • 2020 American Transplant Congress

    Novel Biomarkers for Post-Transplant Recurrent IgA Nephropathy

    Y. Caliskan1, B. Dirim2, E. Aksoy2, R. Ouseph1, Y. Ozluk3, H. Randall4, F. Savran Oguz5, A. Turkmen2, M. S. Sever2, K. Lentine1

    1Division of Nephrology, Saint Louis University, Saint Louis, MO, 2Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, 3Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, 4Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, 5Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey

    *Purpose: The aim of this study is to evaluate serum levels of galactose-deficient IgA1 (Gd-IgA1), advanced oxidation protein products (AOPP) and 4 tag single-nucleotide variants…
  • 2020 American Transplant Congress

    Interstitial Inflammation with Chronic Allograft Injury Best Predicts Graft Loss

    M. Ajaimy, M. Parides, A. Colovai, Y. Azzi, L. Liriano Ward, P. Nandigam, J. Rocca, M. Kinkhabwala, S. Greenstein, J. Graham, E. Akalin

    Einstein-Montefiore Transplant Center, Bronx, NY

    *Purpose: We aimed to identify clinical, serological and histopathological predictors of graft loss in kidney transplant recipients who underwent clinically indicated graft biopsies for worsening…
  • 2020 American Transplant Congress

    Development of Novel Multivariable Logistic Regression Model for Predicting Graft Failure within 2 Weeks and 4 Weeks after Liver Transplantation Using Post-Transplantation Laboratory Values

    J. Kwon, S. Kim, G. Choi, J. Joh, J. Park, J. Rhu, K. Kim, O. Lee, M. Lim, E. Jeong, J. Yang

    Transplantation, Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: This study designed a prediction model for graft failure after liver transplantation.*Methods: Multivariable logistic regression including aspartate aminotransferase (AST), total bilirubin (TB), and international…
  • 2020 American Transplant Congress

    The Evolution and Impact of ABMR Histology and Transplant Glomerulopathy in the Presence or Absence of HLA-DSA

    M. Coemans1, A. Senev1, G. Verbeke2, M. Emonds1, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat), KU Leuven, Leuven, Belgium

    *Purpose: After kidney transplantation, the occurrence of ABMRh (=histological picture of antibody-mediated rejection) and transplant glomerulopathy (cg) has been reported, both in the presence and…
  • 2020 American Transplant Congress

    Hepatic Artery Thrombosis in the Modern Era of Increased Utilization of Livers from Older Donors

    A. Kernodle, M. Krach, P. Chiang, D. Segev, A. Massie, J. Garonzik-Wang

    Johns Hopkins Hospital, Baltimore, MD

    *Purpose: In a prior study using national registry data, deceased donor age greater than 50 was associated with a 35% to 61% increased risk of…
  • 2020 American Transplant Congress

    Kidney Transplantation in Inherited Kidney Diseases

    Y. Caliskan1, H. Yazici2, R. Ouseph1, Y. Ozluk3, H. Randall4, E. Demir2, F. Savran Oguz5, A. Turkmen2, M. S. Sever2, K. Lentine1

    1Division of Nephrology, Saint Louis University, Saint Louis, MO, 2Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, 3Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, 4Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, 5Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey

    *Purpose: We aimed to evaluate the kidney transplant (KTx) recipients with inherited kidney diseases and investigate the causal genetic variants in recipients with undetermined etiology.*Methods:…
  • 2020 American Transplant Congress

    What Are the Peri-Operative and Longterm Outcomes of Utilizing Donation after Circulatory Death Livers with Macrosteatosis? A Multicenter Analysis

    K. Croome1, A. Mathur2, S. Mao1, B. Aqel3, P. Senada1, J. Piatt1, J. Heimbach4, A. Moss3, C. Rosen4, C. Taner1

    1Mayo Clinic Jacksonville, Jacksonville, FL, 2Mayo Clinic Arizona, Scotsdale, AZ, 3Mayo Clinic Arizona, Scottsdale, AZ, 4Mayo Clinic Rochester, Rochester, MN

    *Purpose: Given the potentially additive risk from using donor livers that are both steatotic and from a donation after circulatory death(DCD) donor, there is a…
  • 2020 American Transplant Congress

    Decoding the Troubled Allograft: Proteinuria within the 1st Post-Transplant Year Associates with and Risk Stratifies Inflamed Renal Transplants

    A. Cherukuri, R. Mehta, A. Tevar, R. Munjal, K. Kalra, C. Puttarajappa, P. Sood, C. Wu, S. Hariharan

    Starzl Transplantation Institute, UPMC, Pittsburgh, PA

    *Purpose: The relationship between progression of proteinuria and allograft histology through the 1st year with clinical outcomes is unclear.*Methods: Here, we systematically studied proteinuria {early…
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