Articles tagged "Graft failure"

2021 American Transplant Congress
Drones and Airplanes: Modeling the Potentially Deleterious Effects of Transportation on Shipped Organs
Y. S. Lee, J. S. Bromberg, J. R. Scalea
Surgery, University of Maryland, Baltimore, MD
*Purpose: During the first shipments of human organs by drone, we identified significant differences in pressure and vibration that may adversely affect shipped organs. Liver…
2021 American Transplant Congress
Kidney Transplantation Outcomes Over Last Six Decades- A Single-center Experience
A. Dinesh¹, S. Jackson², A. Matas¹
¹University of Minnesota Medical School, Minneapolis, MN, ²Analytics Consulting Services, M Health Fairview, Minneapolis, MN
*Purpose: During the last 6 decades, the science around kidney transplantation has evolved tremendously resulting in significant improvements in kidney allograft and patient survival. There…
2021 American Transplant Congress
Acute Kidney Injury Requiring Dialysis in Heart Transplant Recipients is a Risk Factor for Graft Failure and Overall Mortality
M. A. Merzkani, H. Murad, A. Pottebaum, A. Java, A. Malone, J. Schilling, A. Itoh, R. Delos Santos, T. Alhamad
Transplant, Washington University, Saint Louis, MO
*Purpose: Acute Kidney Injury (AKI) is a frequent complication of heart transplantation. However, with recent allocation changes, we have increasingly complex patients with a higher…
2021 American Transplant Congress
Development of a Lateral Flow Assay Detecting CXCL9 within Antibody Mediated and Acute T Cell Mediated Rejections After Kidney Transplantation
L. K. Seiler¹, R. Jonczyk¹, P. Lindner¹, L. Phung¹, C. Falk², C. Blume¹
¹Faculty of Natural Sciences, Institute of Technical Chemistry, Hannover, Germany, ²Institute of Transplant Immunology, Medical School Hannover, Hannover, Germany
*Purpose: Despite tremendous improvements in quality and tolerability of immunosuppressive medications after successful kidney transplantation, numerous kidney grafts undergo acute and chronic rejections with following…
2021 American Transplant Congress
Transplant Center Volume in High-risk Recipient Association with Graft and Patient Survival
M. A. Merzkani, H. Murad, M. Mattu, S. Husami, M. Wang, V. Hu, S. Chang, T. Alhamad
Transplant, Washington University, Saint Louis, MO
*Purpose: Evaluation of high-risk recipients in transplant centers involves an intensive multidisciplinary medical evaluation and requires extensive coordination amongst various teams to follow-up on these…
2021 American Transplant Congress
Oxalate Nephropathy After Kidney Transplant: Defining Histological Patterns, Contributing Factors and Graft Outcome
N. Jakob¹, A. Chuu¹, J. Ninan¹, E. Lim¹, N. Zhang¹, H. Amer², F. Cosio², H. Wadei³, M. Ryan¹, C. Cortese³, L. Cornell², M. Keddis¹
¹Nephrology, Mayo Clinic, Scottsdale, AZ, ²Nephrology, Mayo Clinic, Rochester, MN, ³Nephrology, Mayo Clinic, Jacksonville, FL
*Purpose: The objective of this study is to evaluate KTx recipients with biopsy proven oxalate nephropathy (ON) to better define risk factors, histologic patterns and…
2021 American Transplant Congress
Effect of Defibrotide on Kidney Ischemia Reperfusion Injury in a Preclinical Renal Transplant Model
P. Pine¹, Z. Sun², A. Matas³, J. Shi¹, A. Ebrahimnejad¹, M. Zanette⁴, P. Halloran⁵, J. S. Bromberg⁶, R. Hanvesakul⁷
¹Jazz Pharmaceuticals, Palo Alto, CA, ²Johns Hopkins Medicine, Baltimore, MD, ³Univ of Minnesota, Minneapolis, MN, ⁴Jazz Pharmaceuticals, Philadelphia, PA, ⁵Univ of Alberta, Edmonton, AB, Canada, ⁶Univ of Maryland School of Medicine, Baltimore, MD, ⁷Jazz Pharmaceuticals, Oxford, United Kingdom
*Purpose: Ischemia reperfusion injury (IRI) is a major contributor to graft failure. During organ removal and preservation, ischemia results in anaerobic respiration and cellular damage.…
2021 American Transplant Congress
The Importance of Persistent and Recurrent T Cell Mediated Rejection in Tacrolimus Treated Renal Transplant Recipients
C. Rampersad¹, I. W. Gibson², D. N. Rush¹, D. Pochinco³, P. E. Birk⁴, A. Goldberg⁴, T. Blydt-Hansen⁵, M. Karpinski¹, J. Shaw¹, J. Ho¹, P. W. Nickerson¹, C. Wiebe¹
¹Department of Medicine, University of Manitoba, Winnipeg, MB, Canada, ²Department of Pathology, University of Manitoba, Winnipeg, MB, Canada, ³Shared Health Services Manitoba, Winnipeg, MB, Canada, ⁴Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada, ⁵Department of Pediatrics, University of British Columbia, Winnipeg, MB, Canada
*Purpose: Optimal follow-up after treatment for T-cell mediated rejection (TCMR) is not well-established. We sought to identify the prevalence and clinical associations of repeated TCMR…
2020 American Transplant Congress
Analyzing Causes for Death-Censored Graft Failure
M. Mayrdorfer, L. Liefeldt, N. Lachmann, W. Düttmann-Rehnolt, F. Halleck, M. G. Naik, P. Glander, K. Budde
Charité Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Since it has been proposed that several causes could contribute to graft loss (GL), we analyzed graft failure in our center and attributed a…
2020 American Transplant Congress
Long Term Vasculobiliary Problems Associated with Hepatic Artery Stenosis Following Liver Transplant
R. Seth, T. Perera
Queen Elizabeth Hospital, Birmingham, United Kingdom
*Purpose: Hepatic artery stenosis (HAS) is a recognized vascular complication of liver transplant (LT) which can result in significant morbidity and mortality. Despite that there…