Articles tagged "Graft failure"

2021 American Transplant Congress
Covid-19 Incidence Was Initially Associated with Posttransplant Kidney Graft Failure
A. Wey¹, J. Miller¹, D. Musgrove¹, N. Salkowski¹, M. Tabaka¹, R. Hirose², A. Massie³, D. Segev³, A. Israni¹, J. Snyder¹, B. Kasiske¹
¹SRTR, Minneapolis, MN, ²Univ of San Francisco, San Francisco, CA, ³Johns Hopkins, Baltimore, MD
*Purpose: To better understand the effect of COVID-19 on kidney posttransplant outcomes, we estimated the association of county-level COVID-19 incidence with kidney posttransplant graft failure.*Methods:…
2021 American Transplant Congress
The Impact of Donor Age and Donor-Recipient Age Difference on Living Donor Kidney Transplantation
T. Hiramitsu¹, T. Tomosugi², K. Futamura², M. Okada², N. Goto², T. Ichimori², S. Narumi², Y. Watarai²
¹Nagoya Daini Red Cross Hospital, Myokencho Showaku, Japan, ²Nagoya Daini Red Cross Hospital, Nagoya, Japan
*Purpose: The impact of donor age and donor-recipient age difference on living donor kidney transplantation have not been investigated simultaneously.*Methods: A total 805 adult living…
2021 American Transplant Congress
Outcomes of Simultaneous Pancreas-Kidney Transplants from Donation After Circulatory Death Donors in the UK: A National Registry Analysis
N. Karydis¹, M. Ibrahim², C. Counter², J. Casey³, P. Friend⁴, C. Watson⁵, C. Callaghan¹
¹Nephrology and Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom, ²NHS Blood and Transplant, Bristol, United Kingdom, ³Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom, ⁴Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ⁵Department of Surgery, Addenbrooke's Hospital and Cambridge NIHR Biomedical Research Campus, Cambridge, United Kingdom
*Purpose: The UK is a world leader in the use of pancreases from donation after circulatory death (DCD) donors. However, there is a perception that…
2021 American Transplant Congress
Endothelial-to-Myofibroblast Transition (en-mt) and Low Expression of Capillary Vegf Enhance the Development of Interstitial Fibrosis and Glomerulosclerosis Induced by Microvascular Destruction in Antibody-Mediated Rejection (abmr) Patients
B. Ozdemir¹, E. Akcay¹, A. Ok Atilgan¹, M. Haberal²
¹Department of Pathology, Baskent University, Ankara, Turkey, ²Division of Transplantation, Department of General Surgery, Baskent University, Ankara, Turkey
*Purpose: Interstitial fibrosis (IF) and glomerulosclerosis (GS) are the most important cause of graft loss. Although the rate of microvascular destruction (MVD) is similar in…
2021 American Transplant Congress
The Impact of Living Donors Aged 70 and Older on Living Donor Kidney Transplantation
T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, N. Goto, T. Ichimori, S. Narumi, Y. Watarai
Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan
*Purpose: Due to the discrepancy between the number of patients on the waiting list and oragn supply, living donor kidney transplantation is more required. The…
2021 American Transplant Congress
Hla Antigens and Recurrence of Focal Segmental Glomerulosclerosis in Pediatric Kidney Transplantation
B. I. Shaw¹, A. Ochoa², C. Chan², R. A. Gbadegesin³, A. M. Jackson¹, E. T. Chambers³
¹Surgery, Duke University, Durham, NC, ²Biostatistics and Bioinformatics, Duke University, Durham, NC, ³Pediatrics, Duke University, Durham, NC
*Purpose: Recurrence of focal segmental glomerulosclerosis (FSGS) reduces graft survival yet risk factors remain elusive. While HLA risk alleles are known to be associated with…
2021 American Transplant Congress
Evolving Trends in Risk Profiles and Outcomes in Older Adults Undergoing Kidney Re-Transplantation
S. Sandal¹, J. Ahn², M. Cantarovich¹, N. Chu², D. Segev², M. McAdams DeMarco²
¹McGill University, Montreal, QC, Canada, ²Johns Hopkins University, Baltimore, MD
*Purpose: The half-life of a kidney transplant (KT) is 8-12 years, and a significant proportion of patients end up with graft loss at age ≥65…
2021 American Transplant Congress
Is There a Role for Pre-Operative Angiographic Kidney Embolization Prior to Allograft Nephrectomy?
M. Jacobs¹, R. Stratta¹, D. Harriman², A. Farney¹, J. Rogers¹, G. Orlando¹, A. Reeves-Daniel¹, C. Jay¹
¹Wake Forest Baptist Health, Winston Salem, NC, ²University of British Columbia, Vancouver, BC, Canada
*Purpose: To determine if morbidity associated with allograft nephrectomy (AN) of a failed or diseased kidney transplant (KT) is improved by pre-operative angiographic kidney embolization…
2020 American Transplant Congress
Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation
H. Hirao¹, T. Ito¹, K. Nakamura², S. Kageyama¹, K. Kadono¹, H. Kojima¹, K. J. Dery¹, S. Younan¹, R. W. Busuttil¹, F. M. Kaldas¹, J. W. Kupiec‐Weglinski¹
¹UCLA, Los Angeles, CA, ²Kyoto University, Kyoto, Japan
*Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
2020 American Transplant Congress
Renal Allograft Outcome from Hypertensive Donor: Comparison between Living and Deceased Donor
H. Hwang¹, J. Kong¹, J. Kim¹, Y. Kim¹, J. Moon¹, K. Jeong¹, S. Song², S. Song³, H. Shin⁴, J. Yang⁵, C. Ahn⁶, Y. Lee⁷, S. Lee¹
¹Division of Nephrology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ²Pusan National University Hospital, Pusan, Korea, Republic of, ³Ewha Womans University Medical Center, Seoul, Korea, Republic of, ⁴Kosin University College of Medicine, Pusan, Korea, Republic of, ⁵Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ⁶Department of Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of, ⁷Division of Nephrology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seoul, Korea, Republic of
*Purpose: Donor shortage is a serious problem in renal transplantation, and hypertensive living donor is potential candidates to expand donor pool. However, it is not…