ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Glomerulonephritis"

  • 2017 American Transplant Congress

    Impact of Induction Immunosuppression on the Recurrence of Primary IgA Nephropathy.

    K. Lee, C. Cho, N. Lee, K. Kim, S. Kim, J. Lee, J. Lee, H. Park, J. Park, S. Kim.

    Department of Surgery, Samsung Medical Center, Seoul, Korea

    PurposeIgA nephropathy (IgAN) may recur after kidney transplantation (KT) and potentially jeopardize the survival of the graft. The object of this study was to analyze…
  • 2017 American Transplant Congress

    Daratumumab for Severe Refractory Proliferative Glomerulonephritis with Monoclonal Immune Deposits (PGNMID).

    S. Anand,1,3 D. Miller,1 G. Chipman,2 D. Morris,1,3 T. Srinivas.1

    1Intermountain Medical Center, Salt Lake City, UT; 2Utah Cancer Specialists, Salt Lake City, UT; 3Nephrology Assoxiates of Utah, Salt Lake CIty, UT

    Introduction-We report as case of refractory PGNMID treated succesfully with anti-CD38 antibody (Daratumumab). Case report-65 year old male with ESRD attributed to to post infectious…
  • 2017 American Transplant Congress

    Novel Insights into the Synergism of CD40 Autoantibodies and suPAR in Kidney Transplant Patients with FSGS Recurrence.

    T. Sigdel, C. Wei, F. Vencenti, J. Reiser, M. Sarwal.

    University of California San Francisco, San Francisco

    Background: FSGS is a histopathological lesion that has a 40-80% risk of recurrence o in the transplanted (tx) kidney, with increased risk of graft loss.…
  • 2017 American Transplant Congress

    Long-Term Malignancy Risk in Kidney Transplant Recipients Treated with Cyclophosphamide Pre-Transplant for Native Glomerular Disease.

    J. Mills,1 M. Jorgenson,1 J. Fose,1 B. Astor,2 S. Panzer.2

    1Pharmacy, UW Health, Madison, WI; 2Nephrology, UW Health, Madison, WI

    Purpose: To evaluate the incidence of malignancy in kidney transplant recipients who previously received cyclophosphamide for treatment of native glomerular disease.Methods: Single center study of…
  • 2017 American Transplant Congress

    Transcriptome Analysis of CD4-Lymphocyte Specifically Deleted of IKKbeta or NEMO in an Experimental Model of Rapid Progressive Glomerulonephritis (RPGN).

    F. Thaiss,1 J. Huang,2 M. Chen,1 H. Paust,1 G. Zahner,1 M. Alawi,2 R. Geffers,3 L. Guo.1

    1Nephrology, Univ. Hospital UKE, Hamburg, Germany; 2Bioinformatics, Univ. Hospital UKE, Hamburg, Germany; 3Genomics, Helmholtz Center Infection, Braunschweig, Germany

    RPGN is T-cell mediated and can recur after kidney transplantation. T-cell receptor stimulation leads to intracellular signaling events ultimately causing activation of transcription factors such…
  • 2017 American Transplant Congress

    Recurrence of IgA Nephropathy After Kidney Transplantation in Maintenance Steroids versus Steroid Avoidance Regimens: A UNOS/OPTN Analysis.

    N. Leeaphorn, N. Garg, E. Khankin, F. Cardarelli, M. Pavlakis.

    Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA

    Background: There has been an increase in the use of steroid-avoidance regimens. However, there is some evidence to suggest that steroid avoidance may be associated…
  • 2017 American Transplant Congress

    Novel Classification of Membranoproliferative Glomerulonephritis Pattern of Injury in Renal Allograft Based on Immunofluorescence Microscopy: Precise Diagnosis and Prognosis Analysis.

    J. Wen, X. Li, M. Zhang, F. Xu, X. Ni, J. Chen, Z. Tang, Z. Liu.

    National Clinical Research Center of Kidney Diseases, Jinling Hospital, Medical School of Nanjing University, Nanjing, China

    Background: Membranoproliferative glomerulonephritis (MPGN) after renal transplantation is a pattern of injury with heterogenous etiologies. Novel classification of MPGN based on the Immunofluorescence microscopy was…
  • 2016 American Transplant Congress

    Factors Associated with Response to Plasmapheresis in Patients with Recurrent FSGS.

    J. Shoji,1 V. Tatapudi,2 Z. Laszik,1 A. Jones,3 J. Wolf,4 D. Adey,1 F. Vincenti.1

    1Department of Medicine, Division of Nephrology, University of California-San Francisco, California, CA; 2Department of Medicine, Division of Nephrology, New York University, New York, NY; 3Department of Sociology, George Washington University, Washington, DC; 4Transplant Surgery, Piedmont Transplant Institute, Atlanta, GA.

    Background:Idiopathic focal segmental glomerulosclerosis (FSGS) is one of the primary glomerular diseases that commonly recurs in renal allograft and is known to be associated with…
  • 2016 American Transplant Congress

    Graft Loss Due to Recurrence of Focal Segmental Glomerulosclerosis in Second Renal Transplant.

    V. Aggarwal, A. Gruessner, R. Gruessner, V. Whittaker, S. Narsipur.

    Transplant, Upstate Medical University, Syracuse, NY.

    Introduction : Focal segmental glomerular sclerosis (FSGS) glomerulonephritis can recur in renal transplants, and can potentially lead to graft loss. The rate of graft loss…
  • 2016 American Transplant Congress

    Treatment of Post-Transplant Focal Glomerulosclerosis: The Effect on Histopathology Lesions and Podocyte Foot Process Effacement.

    K. Koutroutsos,1 J. Moss,2 L. Moran,2 T. Cook,2 R. Charif,1 D. Taube,1 C. Roufosse,2 M. Loucaidou.1

    1Renal and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with increased risk for renal allograft failure. It has been reported in the literature that podocyte foot…
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