2017 American Transplant Congress
Transcriptome Analysis of CD4-Lymphocyte Specifically Deleted of IKKbeta or NEMO in an Experimental Model of Rapid Progressive Glomerulonephritis (RPGN).
RPGN is T-cell mediated and can recur after kidney transplantation. T-cell receptor stimulation leads to intracellular signaling events ultimately causing activation of transcription factors such…2017 American Transplant Congress
Recurrence of IgA Nephropathy After Kidney Transplantation in Maintenance Steroids versus Steroid Avoidance Regimens: A UNOS/OPTN Analysis.
Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA
Background: There has been an increase in the use of steroid-avoidance regimens. However, there is some evidence to suggest that steroid avoidance may be associated…2017 American Transplant Congress
Novel Classification of Membranoproliferative Glomerulonephritis Pattern of Injury in Renal Allograft Based on Immunofluorescence Microscopy: Precise Diagnosis and Prognosis Analysis.
Background: Membranoproliferative glomerulonephritis (MPGN) after renal transplantation is a pattern of injury with heterogenous etiologies. Novel classification of MPGN based on the Immunofluorescence microscopy was…2017 American Transplant Congress
Acthar in Recurrent Focal Segmental Glomerular Sclerosis After Kidney Transplantation.
1Washington University in St. Louis, St. Louis; 2Johns Hopkins University, Baltimore
Treatment of Recurrent focal segmental glomerular sclerosis (FSGS) after kidney transplantation is challenging with unpredictable outcomes. Conventional therapeutic options include various combinations of plasmapheresis, steroids,…2017 American Transplant Congress
Impact of Induction Immunosuppression on the Recurrence of Primary IgA Nephropathy.
Department of Surgery, Samsung Medical Center, Seoul, Korea
PurposeIgA nephropathy (IgAN) may recur after kidney transplantation (KT) and potentially jeopardize the survival of the graft. The object of this study was to analyze…2017 American Transplant Congress
Daratumumab for Severe Refractory Proliferative Glomerulonephritis with Monoclonal Immune Deposits (PGNMID).
Introduction-We report as case of refractory PGNMID treated succesfully with anti-CD38 antibody (Daratumumab). Case report-65 year old male with ESRD attributed to to post infectious…2017 American Transplant Congress
Novel Insights into the Synergism of CD40 Autoantibodies and suPAR in Kidney Transplant Patients with FSGS Recurrence.
University of California San Francisco, San Francisco
Background: FSGS is a histopathological lesion that has a 40-80% risk of recurrence o in the transplanted (tx) kidney, with increased risk of graft loss.…2016 American Transplant Congress
Insights into the Treatment of Post-Transplant Focal Glomerulosclerosis: Experience Gained from a Concise Diagnostic and Management Protocol.
Background: Recurrence of Focal Glomerulosclerosis (FSGS) after kidney transplantation is associated with poor graft survival. We present results from a concise diagnostic and management protocol…2016 American Transplant Congress
Recurrence of FSGS Post Kidney Transplantation: Salvage Therapy with ACTHAR® Gel.
Transplant, Emory University, Atlanta, GA.
Recurrence of FSGS post kidney transplantation: Salvage therapy with ACTHAR® gel.Introduction:Recurrence of FSGS post kidney transplantation may reach 25-50%. Failure of treatment or incomplete remission…2016 American Transplant Congress
Sequential and Long-Term Protocol Biopsy Is Useful for the Detection of Subclinical Lesions of Clinical Interest in Kidney Allografts.
Objectives: Detection of subclinical lesions is important to overcome the obstacles to improve long-term graft survival after kidney transplantation. The aim of this study was…
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