Articles tagged "Glomerular filtration rate (GFR)"

2018 American Transplant Congress
Long-Term Renal Function in Living Kidney Donors with Renal Cysts
M. Waldram, A. Thomas, A. Muzaale, C. Holscher, A. Nguyen, S. Halpern, S. Anjum, J. Alejo, B. Boyarsky, S. Ottman, J. Garonzik-Wang, D. Segev, A. Massie.
JHU, Baltimore.
Renal cysts found during the evaluation of living kidney donor (LKD) candidates are often regarded as benign. However, it is possible that these structural abnormalities…
2018 American Transplant Congress
Equivalent Post-Donation eGFR after Robotic Assisted versus Laparoscopic Living Donor Nephrectomy
R. Cross, H. Pollinger, M. Tan, M. Mulloy, T. Ommert, A. Ray, C. Klein.
Piedmont Transplant Institute, Atlanta, GA.
Robotic assisted donor nephrectomy (RADN) has gained popularity in recent years as a minimally invasive alternative to traditional laparoscopic donor nephrectomy (LDN). RADN offers advantages…
2018 American Transplant Congress
Shared Genetic Ancestry as a Predictor of Medium Term Renal Transplant Outcome in Deceased Donor Transplants
C. Stapleton,¹ On behalf of the UK and Ireland Renal Transplant Consortium, P. Conlon,² G. Cavalleri.¹
¹Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland; ²Department of Nephrology, Beaumont Hospital, Dublin, Ireland.
Sibling transplant pairs have better transplant outcomes than unrelated donor recipient (DR) pairs indicating that shared genetic ancestry between donors and recipients can aid in…
2018 American Transplant Congress
Long-Term Effects of Ketoconazole in Rapid Tacrolimus Metabolizers Post-Renal Transplantation
J. Ching,¹ S. Anders,¹ M. Janusek,¹ L. Hutchinson,¹ A. Freeman,¹ U. Patel,¹ A. Mohammed,⁴ H. Bohorquez.^2,3
¹Department of Pharmacy, Ochsner Clinical Foundation, New Orleans, LA; ²Multi-Organ Transplant Institute, Ochsner Clinical Foundation, New Orleans, LA; ³The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA; ⁴Academic Center, Ochsner Clinical Foundation, New Orleans, LA.
Introduction: Genetic polymorphisms in cytochrome P-450 enzymes can cause variations in tacrolimus (tac) metabolism. Ketoconazole (keto), a potent CYP450 and P-glycoprotein inhibitor, can be used…
2018 American Transplant Congress
Ischemia Reperfusion Injury & Risk for Antibody Mediated Rejection (ABMR) in HLA Sensitized Patients Treated with C1 Esterase Inhibitor (C1INH)
A. Vo,¹ O. Aubert,² J. Choi,¹ N. Ammerman,¹ H. Edmund,¹ A. Peng,¹ R. Najjar,¹ S. Supreet,¹ S. Jordan.¹
¹Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; ²Paris Translational Research for Organ Transplantation, Necker Hospital, Paris, France.
Introduction: Ischemia reperfusion injury (IRI) contributes to delayed graft function (DGF). IRI/DGF in HLA-sensitized (HS) patients likely activates innate and memory injury pathways that may…
2018 American Transplant Congress
Effect and Reasons of Rescue Switch to Belatacept among 73 Calcineurin-Inhibitors Treated Kidney Allograft Recipients – A Three Years Retrospective Cohort, Single Center Study
M. Matignon,¹ C. Dudreuilh,¹ P. Rémy,¹ D. Desvaux,² P. Grimbert.¹
¹Nephrology Transplantation, APHP Henri Mondor, Creteil, France; ²Pathology, APHP Henri Mondor, Creteil, France.
IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…
2018 American Transplant Congress
Estimated GFR at Donor Screening and Achieved Measured GFR after Living Kidney Donation
M. van Londen, J. van der Weijden, S. Bakker, S. Berger, J. Sanders, G. Navis, M. de Borst.
Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, Netherlands.
Study Purpose: Accurate pre-donation renal function estimation is important to minimize the risk of future severe renal function impairment in living kidney donors. Recent studies…
2018 American Transplant Congress
Effects of the Addition of Mycophenolate Mofetil on Renal Outcomes in Liver Transplant Recipients: A Single Center Review
M. Henry, M. Vacha.
Nebraska Medicine, Omaha, NE.
Purpose: To evaluate the use of mycophenolate mofetil (MMF) and its effects on renal outcomes in liver transplant recipientsMethods: Adult liver transplant recipients from September…
2018 American Transplant Congress
Probability of Developing Chronic Kidney Disease 1 Year after Living Donor Nephrectomy Correlates with Baseline Kidney Volume and Function
I. Hall, A. Shaaban, S. Beddhu, F. Shihab.
University of Utah, Salt Lake City, UT.
Purpose: Living kidney donor outcomes are tremendously important, especially given expanding donor eligibility. Relative to other predictors, the relationship between remaining kidney volume and post-donation…
2018 American Transplant Congress
Comprehensive Assessment of NSAID Use and Potential Nephrotoxicity Risk in Adult Veteran Kidney Transplant Recipients
J. Chiasson, C. Fominaya, M. Gebregziabher, D. Taber.
Ralph H Johnson VAMC, Charleston, SC.
Background: NSAID use is generally recommended to be avoided in kidney transplantation (KTX), but there is paucity in the studies assessing their safety within this…