Articles tagged "Genomic markers"

2015 American Transplant Congress
Non-Chimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers
J. Leventhal,¹ J. Mathew,¹ D. Salomon,² S. Kurian,² J. Friedewald,¹ L. Gallon,¹ I. Konieczna,¹ A. Tambur,¹ J. Levitsky,¹ Y. Kanwar,¹ C. Jie,¹ M. Abecassis,¹ J. Miller.¹
¹CTC, Northwestern University, Chicago, IL; ²Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, CA.
Background. We previously described 3-year results of a non-chimeric tolerance protocol in HLA-identical living donor renal transplant (RT) recipients and now report on longer term,…
2015 American Transplant Congress
APOL1 Risk Alleles in Live and Deceased Kidney Donors Are Associated With Shorter Renal Allograft Survival
M. Doshi,¹ M. Goggins,² S. Norman,³ S. Ho,⁴ C. Winkler,⁵ J. Kopp.⁶
¹Medicine, Wayne State University, Detroit, MI; ²Medicine, Henry Ford Transplant Institute, Detroit, MI; ³Medicine, University of Michigan, Ann Arbor, MI; ⁴Gift of Life, Ann Arbor, MI; ⁵NCI, NIH, Bethesda, MD; ⁶NIDDK, NIH, Bethesda, MD.
Kidneys from African American (AA) donors with two Apolipoprotein L1 (APOL1) risk alleles may be at higher risk of allograft loss after transplant. We sought…
2015 American Transplant Congress
Application of Second Generation Sequencing and AlloAntibody Screening to the Organ Transplantation Arena
B. Keating,¹ Y. Li,¹ K. Olthoff,¹ J. Wang,² A. Shaked.¹
¹Surgery (Division of Transplantation), University of Pennsylvania, Philadelphia, PA; ³Genomics, BGI, Shenzhen, China.
Over the last two decades, over 300,000 solid organ transplantations have been performed in the USA alone. While there has been considerable progress with immunosuppression…