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Articles tagged "Genomic markers"

  • 2015 American Transplant Congress

    Clinical Use of Gene-Expression Profiling to Monitor for Rejection After Cardiac Transplantation – Which Patients and When?

    J. Teuteberg,1 M. Shullo,1 T. Wolf,2 P. Prasad,2 G. Ewald.3

    1University of Pittsburgh Medical Center, Pittsburgh, PA; 2CareDx, Inc., Brisbane, CA; 3Washington University, St. Louis, MO.

    Background: Gene-expression profiling (GEP), in place of endomyocardial biopsy, is increasing. GEP testing is intended for low-risk asymptomatic patients (pts); thus, the profile of pts…
  • 2015 American Transplant Congress

    Donor-Derived Cell-Free DNA Is Stable in Non-Rejecting Heart Transplant Recipients in the CARGO II Multicenter Trial

    D. Hiller,1 M. Grskovic,1 J. Beausang,1 R. Sit,1 B. Christie,1 J. Elechko,1 R. Woodward,1 J. Yee,1 H. Eisen.2

    1CareDx, Inc, Brisbane, CA; 2Drexel University, University of Philadelphia, Philadelphia, PA.

    Purpose: An elevated fraction of donor-derived cell-free DNA (dd-cfDNA) detected in the venous blood of recipients has been shown to be correlated to rejection of…
  • 2015 American Transplant Congress

    Can Gene-Expression Profiling Score Help Explain the Adverse Clinical Outcomes Seen in Gender-Mismatched Heart Transplants?

    N. Sulemanjee,1 P. Prasad,2 T. Wolf,2 V. Thohan,1 J. Teuteberg.3

    1Aurora Research Institute, St. Luke's Medical Center, Milwaukee, WI; 2CareDx, Inc., Brisbane, CA; 3University of Pittsburgh Medical Center, Pittsburgh, PA.

    Background: Gene-expression profiling (GEP) testing, in conjunction with clinical assessment, is an established laboratory test intended to aid in the identification of acute cellular rejection…
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