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Articles tagged "Genomic markers"

  • 2015 American Transplant Congress

    The Design and Implementation of a Genome-Wide Genotyping Array Tailored for Transplantation

    B. Keating,1 A. Israni,2 Y. Li,1 M. Holmes,1 K. Birdwell,3 F. Asselbergs,4 A. Shaked.1

    1Surgery (Division of Transplantation), University of Pennsylvania, Philadelphia, PA; 2University of Minnesota, Minneapolis, MN; 3Nephrology, Vanderbilt University, Nashville, TN; 4Cardiology (Division Heart and Lungs), University Medical Center Utrecht, Utrecht, Netherlands.

    Over 570,000 solid organ transplants have been performed in the United States since 1988. Despite significant improvements in transplant outcomes, chronic organ rejection affects up…
  • 2015 American Transplant Congress

    The Association Between Donor & Recipient Gene Variants and Tacrolimus Safety & Efficacy in a Diverse Cohort of Kidney Transplant Recipients

    D. Taber, T. Srinivas, N. Pilch, M. Gebregziabher, L. Egede, P. Baliga, K. Chavin.

    Medical University of South Carolina, Charleston, SC.

    Previous studies have associated donor P-glycoprotein (PGP) gene variants (ABCB1) with risk of developing CNI-toxicity, while also establishing recipient CYP3A5*1 and ABCB1 gene variants are…
  • 2015 American Transplant Congress

    DNA Methylation Classifier Associates With Long-Term Graft Function Post-Kidney Transplantation

    J. Suh,1 D. Maluf, K. Archer,2 T. Lee,1 L. Gallon,3 V. Mas.1

    1UVA, Charlottesville, VA; 2VCU, Richmond, VA; 3Noerthwestern University, Chicago, IL.

    "Background. Late graft failure is a major problem after kidney transplantation (KT) mainly due to chronic renal allograft dysfunction (CRAD). Data about common pathways of…
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