ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Ganciclovir"

  • 2019 American Transplant Congress

    De-Novo Letermovir Resistant Mutations in Cytomegalovirus-Infected Tissues of Solid Organs Transplant Recipients

    S. HAN, H. Cho, S. Min, Y. Hong

    Internal Medicine, Yonsei University Health System, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Letermovir, cytomegalovirus (CMV) DNA-terminase complex (UL51, UL56, and UL89) inhibitor, revealed the efficient prophylactic effect against CMV infection including disease and DNAemia with low-grade…
  • 2019 American Transplant Congress

    Real World Data Support International Consenus Guidelines on Management of CMV after Kidney Transplantation

    A. Asberg, G. B. Kro, A. V. Reisæter, A. Hartmann, K. Midtvedt

    Oslo University Hospital - Rikshospitalet, Oslo, Norway

    *Purpose: Cytomegalovirus (CMV) naïve kidney transplant recipients (R-) transplanted with an organ from a CMV positive donor (D+) are at high risk for CMV disease.…
  • 2019 American Transplant Congress

    Ganciclovir Based Prophylaxis against Cytomegalovirus Viremia in Pediatric Renal Transplant Patients: A Systematic Review and Meta-Analysis

    B. CHATANI1, W. Glaberson2, Z. Nemeth3, L. Tamariz4, I. A. Gonzalez1

    1Pediatric Infectious Disease, University of Miami Miller School of Medicine, Miami, FL, 2Pediatric Nephrology, University of Miami Miller School of Medicine, Miami, FL, 3Health Informatics, University of Miami Miller School of Medicine, Miami, FL, 4Population Health and Computation Medicine, University of Miami Miller School of Medicine, Miami, FL

    *Purpose: Cytomegalovirus (CMV) disease continues to stand as a significant threat to the longevity of renal transplants in children. More pediatric recipients are CMV negative…
  • 2018 American Transplant Congress

    An Individualized Strategy Using Virus and Immune-Based Markers to Prevent Cytomegalovirus Disease after Face Transplantation

    R. Razonable, H. Amer, S. Mardini.

    Mayo Clinic, Rochester, MN.

    Introduction: There is limited data on CMV prevention after face transplantation. We report an individualized approach using prophylaxis followed by surveillance and preemptive therapy guided…
  • 2018 American Transplant Congress

    Recovery of Wild-Type Genotype after Documented Ganciclovir-Resistance in Transplant Recipients with Recurrent CMV Viremia

    J. Fose, M. Jorgenson, Z. Degrave, R. Redfield, J. Smith, D. Mandelbrot.

    University of Wisconsin Hospital, Madison; University of Wisconsin School of Medicine and Public Health, Madison.

    Purpose: Ganciclovir-resistant cytomegalovirus (GR-CMV) is serious complication after transplantation. Recurrence after primary GR-CMV infection is common, with literature defined rates of approximately 20-30%. It is…
  • 2018 American Transplant Congress

    Multidisciplinary Approach to Prevention of Cytomegalovirus (CMV) Complications in Kidney and Liver Transplant Recipients

    S. Shoham,1 S. Anderson,2 R. Avery,1 M. Belden,3 L. Boyer,3 W. Cochran,3 N. Desai,1 M. Holechek,3 E. Kraus,1 J. Langlee,3 P. Spitz,2 K. Marr.1

    1Johns Hopkins University School of Medicine, Baltimore, MD; 2IT@JH Epic, JHMI: Johns Hopkins Health System, Baltimore, MD; 3Comprehensive Transplant Center, JHMI: Johns Hopkins Hospital, Baltimore, MD.

    Background: CMV infection can be prevented in most SOT recipients providing that a prevention protocol is followed. We discovered that our center's protocol, which includes…
  • 2018 American Transplant Congress

    Cytomegalovirus Prophylaxis Following Alemtuzumab Induction in High Risk Renal Transplant Recipients Experiencing Delayed Graft Function

    S. Freedman, B. Ravichandran, B. Masters, E. Heil, K. Saharia, J. Bromberg, A. Haririan, T. Sparkes.

    University of Maryland, Baltimore.

    Purpose: There is limited data to support the use of valganciclovir in patients on dialysis. This study assessed the efficacy of valganciclovir 450 mg twice…
  • 2018 American Transplant Congress

    Evaluation of the Use of Oral Valganciclovir for the Treatment of Cytomegalovirus Infections in Pediatric Intestinal Transplant Recipients: A Single Center Review

    M. Henry, M. Vacha, M. Keck, D. Florescu.

    Nebraska Medicine, Omaha, NE.

    Purpose: To evaluate the safety and efficacy of oral valganciclovir in treating cytomegalovirus (CMV) infections in pediatric intestinal transplant recipients (pITR).Methods: This retrospective review included…
  • 2017 American Transplant Congress

    Utility of “High-Dose” Ganciclovir in High Viral Load CMV Infection in Transplant Recipients.

    M. Alfares, R. Avery, N. Turki, K. Alfares, S. Mehta, R. Boger, A. Valsamakis.

    Transplant & Oncology Infectious Disease, Johns Hopkins, Baltimore, MD; Transplant & Oncology Infectious Disease, Johns Hopkins, Baltimore, MD; Transplant & Oncology Infectious Disease, Johns Hopkins, Baltimore, MD; Transplant & Oncology Infectious Disease, Johns Hopkins, Baltimore, MD; Transplant & Oncology Infectious Disease, Johns Hopkins, Baltimore, MD; Pediatric Infectious Disease, Johns Hopkins, Baltimore, MD; Pathology, Johns Hopkins, Baltimore, MD

    Background: High-dose ganciclovir (GCV) is often used for treatment of high viral load CMV, but few data exist on virologic outcomes and risk of neutropenia.…
  • 2017 American Transplant Congress

    Ganciclovir Resistant Cytomegalovirus Infection in Abdominal Tansplant Recipients.

    J. Fose, M. Jorgenson, K. Rolling, E. McCreary, D. Mandelbrot, J. Smith.

    University of Wisconsin Hospital and Clinics, Madison

    Purpose: Single center evaluation of ganciclovir-resistant cytomegalovirus (GR-CMV) incidence, treatment and outcomes.Methods: Review of adult abdominal transplant (aSOT) recipients from 1/1/1995-12/31/2015 with documented GR-CMV infection.Results:…
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