ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Fungal infection"

  • 2017 American Transplant Congress

    Outcomes Following Reduction of Immunosuppression in Solid Organ Transplant Recipients with Cryptococcosis.

    P. Bryant,1 P. Pappas,1 C. Huisingh,1 R. Mannon,1 J. Locke,1 K. Wille,1 D. Eckhoff,1 J. Tallaj,1 J. Baddley.1,2

    1Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL; 2VAMC, Birmingham, AL

    Background: Cryptococcosis (crypto) is the third most common fungal infection in solid organ transplant (SOT) recipients. Although reduction of immunosuppression (IS) may improve patient outcomes…
  • 2017 American Transplant Congress

    MicroRNAs and Long Non-Coding RNAs as Potential Novel Biomarkers in Transplanted Patients with Candida Infection.

    A. Yang,1 C. Zhou,2 D. Li,3 W. Ju,1 Z. Guo,1 L. Wu,1 A. Hu,1 Y. Ma,1 D. Wang,1 X. Zhu,1 X. He.1

    1Organ Transplantation Center, The First Affiliated Hospital of Sun Yat -sen University, Guangzhou, Guangdong, China; 2Gastroenterology Unit, Massachusetts General Hospital, Boston, MA; 3Ophthalmology, Schepens Research Institute, Boston, MA

    There is an urgent need to develop sensitive and specific biomarkers for the early diagnosis of candida infection in transplanted patients. miRNAs and lncRNAs are…
  • 2017 American Transplant Congress

    Incidence of Fungal and Viral Infections Following Rituximab Use in Kidney Transplant Recipients.

    L. Wong, M. Ison, C. Richardson, K. Cunningham, C. D'Agostino, C. Tseng, A. Shetty.

    Northwestern Memorial Hospital, Chicago, IL

    Rituximab is used off-label in solid organ transplant for desensitization and treatment of antibody-mediated rejection (AMR). It targets CD20 and results in B cell depletion.…
  • 2017 American Transplant Congress

    Risk Factors for Cryptococcal Disease in Transplant as Compared with Non-Transplant Patients: A Single Center Study.

    O. Beaird,1 O. Garner,2 R. Humphries,2 J. Schaenman.1

    1David Geffen School of Medicine at UCLA, Los Angeles, CA; 2UCLA Pathology & Laboratory Medicine, Los Angeles, CA

    Purpose: To examine clinical characteristics of non-HIV, immunocompromised patients diagnosed with cryptococcal disease, including solid-organ transplant (SOT) recipients.Methods: We performed retrospective chart review of non-HIV,…
  • 2017 American Transplant Congress

    Prevalence of Cutaneous Disease in Solid Organ Transplant Recipients: A 5-Year Study from a Medical -Surgical Transplant Dermatology Center.

    R. Allawh, A. Weiffenbach, K. Nadhan, M. Abdelmalek, C. Cusack, C. Chung.

    Dermatology, Drexel University College of Medicine, Philadelphia, PA

    Background: Solid organ transplant recipients (OTR) on chronic immunosuppression exhibit heightened risk of developing a myriad of cutaneous manifestations compared to non-transplant patients, including cutaneous…
  • 2017 American Transplant Congress

    Echinocandins in Lung Transplant Recipients (LTRs).

    Y. AlJishi,1 C. Rotstein,1 D. Kumar,1 A. Humar,1 L. Singer,2 S. Keshavjee,2 S. Husain.1

    1Transplant Infectious Diseases, University Health Network, Toronto, ON, Canada; 2Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada

    Purpose: Echinocandins are a class of antifungal drugs that have activity against Aspergillus species. However, the use of echinocandins in LTRs is not well reported.…
  • 2017 American Transplant Congress

    CCR5-Mediated Recruitment of NK Cells to the Kidney Is Critical for Resistance to Candida albicans Infections.

    J. Lee,1,4 V. Tran,3 H. Kim,1 B. Kwon,1,3 K. Park,1,4 H. Cho.1,2

    1Biomedical Research Center, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, Republic of Korea; 2Department of Surgery, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, South Korea, Republic of Korea; 3School of Biological Sciences, University of Ulsan, Ulsan, South Korea, Republic of Korea; 4Department of Internal Medicine, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, South Korea, Republic of Korea

    We previously showed that CCR5 mediates recruitment of NK cells to the kidney after renal ischemia and reperfusion, which in turn induce the production of…
  • 2016 American Transplant Congress

    Pneumocystis jirovecii Pneumonia: Late and Serious Complication Among Kidney Transplant Recipients.

    L. Viana, T. Sandes, M. Cristelli, A. Oliveira, D. Santos, H. Tedesco-Silva, J. Medina-Pestana.

    HOSPITAL DO RIM-UNIFESP, São Paulo, Brazil.

    We report 50 confirmed PJP cases that occurred in kidney transplant patients between 06/16/2011 and 10/17/2015 in a single center.In the studied period, there were…
  • 2016 American Transplant Congress

    Trends in Aspergillus Infection After Liver Transplantation, 1988-2014.

    R. Al Masri, L. Jennings, S. Asrani, G. Klintmalm, C. Spak.

    Transplant Hepatology/Transplant Surgery/Infectious Disease, Baylor University Medical Center, Dallas, TX.

    Background: Invasive Aspergillosis is an important cause of morbidity and mortality in liver transplant recipients. Aspergillus may account for up to 25% of all fungal…
  • 2016 American Transplant Congress

    Circulating miR-215, miR-let-7c miR-154, miR-193a, NR_036506.1 and NR_027669.1 as Biomarkers Predict Fungal Infection in Post-Transplanted Recipients.

    A. Yang, Z. Guo, W. Ju, C. Zhang, Z. Li, X. Yuan, Q. Zhao, H. Ye, Y. Liao, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aims: The incidence of fungal infection in post-transplanted patients is 13%-17%, which seriously effecting perioperative survival and increasing their economic burden. We wanted to find…
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