Articles tagged "Fungal infection"

2017 American Transplant Congress
Clinical Risk Factors for Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant Recipients (LTRs): Results of an International Cohort Study.
N. Law,¹ B. Hamandi,¹ C. Fegbeutel,² F. Silveira,³ E. Verschuuren,⁴ P. Ussetti,⁵ P. Chin-Hong,⁶ A. Solé,⁷ C.-L. Holmes-Liew,⁸ E. Billaud,⁹ P. Grossi,¹⁰ O. Manuel,¹¹ D. Levine,¹² R. Barbers,¹³ D. Hadjiliadis,¹⁴ L. Singer,¹ S. Husain.¹
¹University Health Network, Toronto, ON, Canada; ²Hannover Medical School, Hannover, Germany; ³University of Pittsburgh, Pittsburgh, PA; ⁴University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ⁵Hospital Puerta de Hierro, Madrid, Spain; ⁶University of California, San Francisco, CA; ⁷University and Polytechnic Hospital La Fe, Universidad de Valencia, Valencia, Spain; ⁸Royal Adelaide Hospital, Adelaide, Australia; ⁹APHP Hopital Européen G Pompidou, Paris, France; ¹⁰University of Insubria, Varese, Italy; ¹¹University Hospital of Lausanne, Lausanne, Switzerland; ¹²University of Texas Health Science Center San Antonio, San Antonio, TX; ¹³KECK Medical Center of University of Southern California, Los Angeles, CA; ¹⁴University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, PA
Introduction:Bronchiolitis obliterates syndrome (BOS) is a major impediment in the long term survival of LTRs. The main objective of this study was to identify infectious…
2017 American Transplant Congress
High Mortality in Transplant Recipients Associated with Coccidioidomycosis Derived from Organ Donors.
N. Jeyakumar,² N. Neidlinger,³ M. Salvatore,³ C. Brown,⁴ T. Carpenter,³ M. Fung,¹ P. Chin-Hong.¹
¹Department of Medicine, University of California, San Francisco, San Francisco, CA; ²Department of Medicine, University of Miami Miller School of Medicine, Miami, FL; ³Donor Network West, San Ramon, CA; ⁴Decision Patterns, Oakland, CA
Purpose Coccidioidomycosis (CI) occurs in 4-9% of solid organ recipients in endemic areas, resulting in 30-63% mortality. CI can be transmitted directly via transplantation, but…
2017 American Transplant Congress
The Feared Five Fungal Infections in Kidney Transplant Recipients: 20-Year Experience at a Midwestern Center.
S. Parajuli, A. Wick, S. Pandeya, B. Astor, J. Smith, A. Djamali, D. Mandelbrot.
University of Wisconsin, Madison, WI
Invasive fungal infections (IFI) are increasing in kidney transplant recipients (KTR). Here we present our experience with five feared IFIs in KTR transplanted between 01/01/1994…
2017 American Transplant Congress
Diagnostic Bronchoscopy in Kidney Transplant Recipients with Acute Respiratory Failure: Risk or Value?
D. Khadzhynov, J. Deissler, F. Halleck, L. Lehner, K. Budde, O. Staeck.
Nephrology, Charité Universitaetsmedizin, Berlin, Germany
Introduction:Few data evaluates the differential diagnostic value of bronchoalveolar lavages (FO-BAL) in kidney transplant recipients (KTR) with acute respiratory failure (ARF). We describe the results…
2017 American Transplant Congress
Outcomes Following Reduction of Immunosuppression in Solid Organ Transplant Recipients with Cryptococcosis.
P. Bryant,¹ P. Pappas,¹ C. Huisingh,¹ R. Mannon,¹ J. Locke,¹ K. Wille,¹ D. Eckhoff,¹ J. Tallaj,¹ J. Baddley.^1,2
¹Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL; ²VAMC, Birmingham, AL
Background: Cryptococcosis (crypto) is the third most common fungal infection in solid organ transplant (SOT) recipients. Although reduction of immunosuppression (IS) may improve patient outcomes…
2017 American Transplant Congress
MicroRNAs and Long Non-Coding RNAs as Potential Novel Biomarkers in Transplanted Patients with Candida Infection.
A. Yang,¹ C. Zhou,² D. Li,³ W. Ju,¹ Z. Guo,¹ L. Wu,¹ A. Hu,¹ Y. Ma,¹ D. Wang,¹ X. Zhu,¹ X. He.¹
¹Organ Transplantation Center, The First Affiliated Hospital of Sun Yat -sen University, Guangzhou, Guangdong, China; ²Gastroenterology Unit, Massachusetts General Hospital, Boston, MA; ³Ophthalmology, Schepens Research Institute, Boston, MA
There is an urgent need to develop sensitive and specific biomarkers for the early diagnosis of candida infection in transplanted patients. miRNAs and lncRNAs are…
2017 American Transplant Congress
Incidence of Fungal and Viral Infections Following Rituximab Use in Kidney Transplant Recipients.
L. Wong, M. Ison, C. Richardson, K. Cunningham, C. D'Agostino, C. Tseng, A. Shetty.
Northwestern Memorial Hospital, Chicago, IL
Rituximab is used off-label in solid organ transplant for desensitization and treatment of antibody-mediated rejection (AMR). It targets CD20 and results in B cell depletion.…
2016 American Transplant Congress
Trends in Aspergillus Infection After Liver Transplantation, 1988-2014.
R. Al Masri, L. Jennings, S. Asrani, G. Klintmalm, C. Spak.
Transplant Hepatology/Transplant Surgery/Infectious Disease, Baylor University Medical Center, Dallas, TX.
Background: Invasive Aspergillosis is an important cause of morbidity and mortality in liver transplant recipients. Aspergillus may account for up to 25% of all fungal…
2016 American Transplant Congress
Circulating miR-215, miR-let-7c miR-154, miR-193a, NR_036506.1 and NR_027669.1 as Biomarkers Predict Fungal Infection in Post-Transplanted Recipients.
A. Yang, Z. Guo, W. Ju, C. Zhang, Z. Li, X. Yuan, Q. Zhao, H. Ye, Y. Liao, X. Zhu, X. He.
Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Aims: The incidence of fungal infection in post-transplanted patients is 13%-17%, which seriously effecting perioperative survival and increasing their economic burden. We wanted to find…
2016 American Transplant Congress
Pneumocystis Pneumonia Following Solid Organ Transplantation, Systematic Review and Meta-Analysis.
S. Hosseini-Moghaddam,^1,2 R. Krishnan.²
¹Medicine, Western University, London, ON, Canada; ²Epidemiology and Biostatistics, Western University, London, ON, Canada.
Background: Different variables have been reported that may increase the risk of pneumocystis pneumonia (PCP) in solid organ transplant patients (SOT).Objectives:To investigate the effect of…