Articles tagged "Fungal infection"

2017 American Transplant Congress
Risk Factors for Cryptococcal Disease in Transplant as Compared with Non-Transplant Patients: A Single Center Study.
O. Beaird,¹ O. Garner,² R. Humphries,² J. Schaenman.¹
¹David Geffen School of Medicine at UCLA, Los Angeles, CA; ²UCLA Pathology & Laboratory Medicine, Los Angeles, CA
Purpose: To examine clinical characteristics of non-HIV, immunocompromised patients diagnosed with cryptococcal disease, including solid-organ transplant (SOT) recipients.Methods: We performed retrospective chart review of non-HIV,…
2017 American Transplant Congress
Prevalence of Cutaneous Disease in Solid Organ Transplant Recipients: A 5-Year Study from a Medical -Surgical Transplant Dermatology Center.
R. Allawh, A. Weiffenbach, K. Nadhan, M. Abdelmalek, C. Cusack, C. Chung.
Dermatology, Drexel University College of Medicine, Philadelphia, PA
Background: Solid organ transplant recipients (OTR) on chronic immunosuppression exhibit heightened risk of developing a myriad of cutaneous manifestations compared to non-transplant patients, including cutaneous…
2017 American Transplant Congress
Echinocandins in Lung Transplant Recipients (LTRs).
Y. AlJishi,¹ C. Rotstein,¹ D. Kumar,¹ A. Humar,¹ L. Singer,² S. Keshavjee,² S. Husain.¹
¹Transplant Infectious Diseases, University Health Network, Toronto, ON, Canada; ²Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada
Purpose: Echinocandins are a class of antifungal drugs that have activity against Aspergillus species. However, the use of echinocandins in LTRs is not well reported.…
2017 American Transplant Congress
CCR5-Mediated Recruitment of NK Cells to the Kidney Is Critical for Resistance to Candida albicans Infections.
J. Lee,^1,4 V. Tran,³ H. Kim,¹ B. Kwon,^1,3 K. Park,^1,4 H. Cho.^1,2
¹Biomedical Research Center, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, Republic of Korea; ²Department of Surgery, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, South Korea, Republic of Korea; ³School of Biological Sciences, University of Ulsan, Ulsan, South Korea, Republic of Korea; ⁴Department of Internal Medicine, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan, South Korea, Republic of Korea
We previously showed that CCR5 mediates recruitment of NK cells to the kidney after renal ischemia and reperfusion, which in turn induce the production of…
2017 American Transplant Congress
Clinical Risk Factors for Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant Recipients (LTRs): Results of an International Cohort Study.
N. Law,¹ B. Hamandi,¹ C. Fegbeutel,² F. Silveira,³ E. Verschuuren,⁴ P. Ussetti,⁵ P. Chin-Hong,⁶ A. Solé,⁷ C.-L. Holmes-Liew,⁸ E. Billaud,⁹ P. Grossi,¹⁰ O. Manuel,¹¹ D. Levine,¹² R. Barbers,¹³ D. Hadjiliadis,¹⁴ L. Singer,¹ S. Husain.¹
¹University Health Network, Toronto, ON, Canada; ²Hannover Medical School, Hannover, Germany; ³University of Pittsburgh, Pittsburgh, PA; ⁴University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ⁵Hospital Puerta de Hierro, Madrid, Spain; ⁶University of California, San Francisco, CA; ⁷University and Polytechnic Hospital La Fe, Universidad de Valencia, Valencia, Spain; ⁸Royal Adelaide Hospital, Adelaide, Australia; ⁹APHP Hopital Européen G Pompidou, Paris, France; ¹⁰University of Insubria, Varese, Italy; ¹¹University Hospital of Lausanne, Lausanne, Switzerland; ¹²University of Texas Health Science Center San Antonio, San Antonio, TX; ¹³KECK Medical Center of University of Southern California, Los Angeles, CA; ¹⁴University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, PA
Introduction:Bronchiolitis obliterates syndrome (BOS) is a major impediment in the long term survival of LTRs. The main objective of this study was to identify infectious…
2017 American Transplant Congress
High Mortality in Transplant Recipients Associated with Coccidioidomycosis Derived from Organ Donors.
N. Jeyakumar,² N. Neidlinger,³ M. Salvatore,³ C. Brown,⁴ T. Carpenter,³ M. Fung,¹ P. Chin-Hong.¹
¹Department of Medicine, University of California, San Francisco, San Francisco, CA; ²Department of Medicine, University of Miami Miller School of Medicine, Miami, FL; ³Donor Network West, San Ramon, CA; ⁴Decision Patterns, Oakland, CA
Purpose Coccidioidomycosis (CI) occurs in 4-9% of solid organ recipients in endemic areas, resulting in 30-63% mortality. CI can be transmitted directly via transplantation, but…
2017 American Transplant Congress
The Feared Five Fungal Infections in Kidney Transplant Recipients: 20-Year Experience at a Midwestern Center.
S. Parajuli, A. Wick, S. Pandeya, B. Astor, J. Smith, A. Djamali, D. Mandelbrot.
University of Wisconsin, Madison, WI
Invasive fungal infections (IFI) are increasing in kidney transplant recipients (KTR). Here we present our experience with five feared IFIs in KTR transplanted between 01/01/1994…
2016 American Transplant Congress
Trends in Aspergillus Infection After Liver Transplantation, 1988-2014.
R. Al Masri, L. Jennings, S. Asrani, G. Klintmalm, C. Spak.
Transplant Hepatology/Transplant Surgery/Infectious Disease, Baylor University Medical Center, Dallas, TX.
Background: Invasive Aspergillosis is an important cause of morbidity and mortality in liver transplant recipients. Aspergillus may account for up to 25% of all fungal…
2016 American Transplant Congress
Circulating miR-215, miR-let-7c miR-154, miR-193a, NR_036506.1 and NR_027669.1 as Biomarkers Predict Fungal Infection in Post-Transplanted Recipients.
A. Yang, Z. Guo, W. Ju, C. Zhang, Z. Li, X. Yuan, Q. Zhao, H. Ye, Y. Liao, X. Zhu, X. He.
Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Aims: The incidence of fungal infection in post-transplanted patients is 13%-17%, which seriously effecting perioperative survival and increasing their economic burden. We wanted to find…
2016 American Transplant Congress
Pneumocystis Pneumonia Following Solid Organ Transplantation, Systematic Review and Meta-Analysis.
S. Hosseini-Moghaddam,^1,2 R. Krishnan.²
¹Medicine, Western University, London, ON, Canada; ²Epidemiology and Biostatistics, Western University, London, ON, Canada.
Background: Different variables have been reported that may increase the risk of pneumocystis pneumonia (PCP) in solid organ transplant patients (SOT).Objectives:To investigate the effect of…