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Articles tagged "Fungal infection"

  • 2019 American Transplant Congress

    Candida auris after Liver Transplant

    N. M. Theodoropoulos, R. Ellison, J. S. Daly, A. Bozorgzadeh, D. A. Mack, L. Gibson, S. M. Levitz

    University of Massachusetts Medical School, Worcester, MA

    *Purpose: C. auris is a difficult to eradicate yeast that has caused outbreaks in hospitals in recent years. We report a cluster of liver transplant…
  • 2019 American Transplant Congress

    CCR5-Mediated Recruitment of NK Cells to the Kidney is a Critical Step for Host Defense to Candida albicans Infection

    H. R. Cho1, V. G. Tran2, N. N. Nguyen3, S. Lee4, S. W. Kang4, J. Kim4, H. J. Kim4, S. J. Park1, J. S. Lee5, B. Kwon6

    1Department of Surgery, Ulsan University Hospital, Ulsan, Korea, Republic of, 2School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea, Ulsan, Korea, Republic of, 31School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea, Ulsan, Korea, Republic of, 4Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea, Republic of, 5Division of Nephrology, Department of Internal Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of, 6Biomedical Research Center, Ulsan University Hospital, School of Medicine, University of Ulsan, Ulsan, Korea, Republic of

    *Purpose: Candida albicans infection causes a high rate of mortality in immunocompromised or transplant patients. In this study, we investigated the role of CCR5 that…
  • 2019 American Transplant Congress

    Evaluation of Infection and Renal Transplant Outcomes in the Hmong Population

    M. Jorgenson1, J. Descourouez1, D. Yang2, G. Leverson2, J. Smith2, R. Redfield2

    1UW Health, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, WI

    *Purpose: Literature suggests the Hmong people to be at higher risk for infection, particularly fungal. The risk of infection after transplant in the Hmong population…
  • 2019 American Transplant Congress

    Risk of Opportunistic Infection in Kidney Transplant Recipients with Cytomegalovirus Infection and Associated Outcomes

    M. Jorgenson1, J. Descourouez1, B. Cardinale2, B. Lyu3, B. Astor3, N. Garg3, C. Saddler3, J. Smith3, D. Mandelbrot3

    1UW Health, Madison, WI, 2University of Wisconsin-Madison School of Pharmacy, Madison, WI, 3University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI

    *Purpose: Cytomegalovirus (CMV) infection in kidney transplant recipients has been anecdotally observed with concomitant or subsequent opportunistic infections (OI), but this association has yet to…
  • 2019 American Transplant Congress

    Azole Use and Fungal Pathogens in Cystic Fibrosis versus Non-Cystic Fibrosis Lung Transplant Recipients

    F. J. Marco Canosa1, K. Brizendine2, H. Hassouna3

    1Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, 2Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, 3Infectious Disease, Spectrum Health Infectious Disease, Grand Rapids, MI

    *Purpose: Cystic fibrosis (CF) patients exhibit unique pharmacokinetic principles. Azole antifungals show marked inter- and intra-patient variability. We aimed to improve itraconazole (ITR) use and…
  • 2019 American Transplant Congress

    Anti-Fungal Prophylaxis in Lung Transplant: A Systematic Review/Meta-Analysis

    K. Pennington, M. Baqir, P. Erwin, H. Murad, R. Razonable, C. C. Kennedy

    Mayo Clinic, Rochester, MN

    *Purpose: Invasive fungal infections (IFI) increase morbidity and mortality after lung transplant. Despite this, anti-fungal prophylaxis (AFP) in lung transplant recipients (LTR) varies by prophylactic…
  • 2018 American Transplant Congress

    Therapeutic Drug Monitoring (TDM) of Suspension (SUS), Extended-Release (ER), and Intravenous (IV) Posaconazole (POS) at a Large Transplant Center

    G. Haidar, R. Shields, C. Clancy, M. Nguyen.

    Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA.

    Background: Data on ER and IV POS among organ transplant recipients (OTRs) are limited, and the role of TDM is unclear.Methods: Retrospective study of patients…
  • 2018 American Transplant Congress

    A Multi-Center Analysis of Risk Factors for Pneumocystis Pneumonia (PCP) in Solid Organ Transplant Recipients

    S. Hosseini-Moghaddam, M. Shokoohi, G. Singh, S. Dufresne, A. Jevnikar, D. Kabbani, H. Cardinal, I. Houde, M-.J. Hebert, A. Shoker, G. Prasad, A. Humar, D. Kumar.

    Medicine, London Health Sciences Centre (LHSC), London, ON, Canada.

    Introduction: Pneumocystis pneumonia (PCP) is associated with morbidity and mortality in solid organ transplant patients (SOTs). There are increasing reports of late PCP in SOT…
  • 2018 American Transplant Congress

    Risk Factors for Invasive Fungal Infections among Lung Transplant Recipients

    K. Whitaker, J. Anesi, E. Blumberg, L. Gardo, J. Lee, M. Crespo, C. Bermudez, L. Glaser, M. Wilck.

    University of Pennsylvania, Philadelphia, PA.

    Objective: Lung transplant (LT) recipients are at high risk of invasive fungal infections (IFI) with an estimated 1-year incidence of 8%. Despite advances in antifungal…
  • 2018 American Transplant Congress

    Pneumocystis jiroveci Pneumonia (PJP) in Kidney and Pancreas Transplant Recipients in the Present Era of Routine Post-Transplant Prophylaxis: Risk Factors and Outcomes

    N. Garg, M. Jorgenson, M. Birschbach, J. Descourouez, S. Parajuli, B. Astor, A. Djamali, D. Mandelbrot.

    University of Wisconsin, Madison.

    PJP after transplant (TX) is associated with substantial morbidity and mortality. In the present era of universal and routine implementation of PJP prophylaxis (PPX) during…
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