ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Fungal infection"

  • 2019 American Transplant Congress

    Target Itraconazole Trough Concentration for Prophylaxis in Lung Transplant

    J. A. Morillas-Rodriguez1, H. Hassouna2, F. Marco-Canosa3, K. D. Brizendine1

    1Infectious disease, Cleveland Clinic, Cleveland, OH, 2Infectious disease, Spectrum health, Grand rapids, MI, 3Cleveland Clinic, Cleveland, OH

    *Purpose: Itraconazole (ITR) therapeutic drug monitoring (TDM) for prophylaxis in lung transplant recipients (LTR) is not well characterized. Our purpose was to evaluate ITR trough…
  • 2019 American Transplant Congress

    Candida auris after Liver Transplant

    N. M. Theodoropoulos, R. Ellison, J. S. Daly, A. Bozorgzadeh, D. A. Mack, L. Gibson, S. M. Levitz

    University of Massachusetts Medical School, Worcester, MA

    *Purpose: C. auris is a difficult to eradicate yeast that has caused outbreaks in hospitals in recent years. We report a cluster of liver transplant…
  • 2019 American Transplant Congress

    CCR5-Mediated Recruitment of NK Cells to the Kidney is a Critical Step for Host Defense to Candida albicans Infection

    H. R. Cho1, V. G. Tran2, N. N. Nguyen3, S. Lee4, S. W. Kang4, J. Kim4, H. J. Kim4, S. J. Park1, J. S. Lee5, B. Kwon6

    1Department of Surgery, Ulsan University Hospital, Ulsan, Korea, Republic of, 2School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea, Ulsan, Korea, Republic of, 31School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea, Ulsan, Korea, Republic of, 4Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea, Republic of, 5Division of Nephrology, Department of Internal Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of, 6Biomedical Research Center, Ulsan University Hospital, School of Medicine, University of Ulsan, Ulsan, Korea, Republic of

    *Purpose: Candida albicans infection causes a high rate of mortality in immunocompromised or transplant patients. In this study, we investigated the role of CCR5 that…
  • 2019 American Transplant Congress

    Evaluation of Infection and Renal Transplant Outcomes in the Hmong Population

    M. Jorgenson1, J. Descourouez1, D. Yang2, G. Leverson2, J. Smith2, R. Redfield2

    1UW Health, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, WI

    *Purpose: Literature suggests the Hmong people to be at higher risk for infection, particularly fungal. The risk of infection after transplant in the Hmong population…
  • 2019 American Transplant Congress

    Risk of Opportunistic Infection in Kidney Transplant Recipients with Cytomegalovirus Infection and Associated Outcomes

    M. Jorgenson1, J. Descourouez1, B. Cardinale2, B. Lyu3, B. Astor3, N. Garg3, C. Saddler3, J. Smith3, D. Mandelbrot3

    1UW Health, Madison, WI, 2University of Wisconsin-Madison School of Pharmacy, Madison, WI, 3University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI

    *Purpose: Cytomegalovirus (CMV) infection in kidney transplant recipients has been anecdotally observed with concomitant or subsequent opportunistic infections (OI), but this association has yet to…
  • 2019 American Transplant Congress

    Azole Use and Fungal Pathogens in Cystic Fibrosis versus Non-Cystic Fibrosis Lung Transplant Recipients

    F. J. Marco Canosa1, K. Brizendine2, H. Hassouna3

    1Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, 2Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, 3Infectious Disease, Spectrum Health Infectious Disease, Grand Rapids, MI

    *Purpose: Cystic fibrosis (CF) patients exhibit unique pharmacokinetic principles. Azole antifungals show marked inter- and intra-patient variability. We aimed to improve itraconazole (ITR) use and…
  • 2018 American Transplant Congress

    Increase in Potentially Resistant Non-Aspergillus Molds Isolated in Lung Transplant Recipients after Voriconazole and Posaconazole Prophylaxis

    M. Fung,1 J. Greenland,2,3 S. Hays,2 J. Singer,2 J. Golden,2 P. Chin-Hong.1

    1Infectious Diseases, University of California San Francisco, San Francisco, CA; 2Pulmonary and Critical Care, University of California San Francisco, San Francisco, CA.

    Background: Lung transplant recipients are at higher risk for invasive fungal infections compared to other solid organs transplant patients. Antifungal prophylaxis with mold-active azoles has…
  • 2018 American Transplant Congress

    Micafungin Prophylaxis in Liver Transplant Recipients at High Risk for Invasive Fungal Infections

    A. Nolan, N. Harriott, K. Startsman.

    Medstar Georgetown University Hospital, Department of Pharmacy, Washington, DC.

    Purpose: This study was conducted to determine the incidence of proven or probable invasive fungal infections in the first 90 days after transplant in high…
  • 2018 American Transplant Congress

    Solid Organ Transplantation and Data Mining: Risk Factors for Invasive Fungal Disease in Heart Transplant Recipients

    N. Barros, D. Xie, C. Yek, T. Liu, X. Li, B. Adams-Huet, J. Martinez, S. Garg, J. Grodin, R. Morelend, A. Amin, F. Aras, J. Thibodeau, P. Mammen, M. Peltz, M. Drazner, W. Ring, R. Haley, R. La Hoz.

    UT Southwestern, Dallas, TX.

    We created a database of solid organ transplant (SOT) recipients using innovative data mining tools. This study describing the epidemiology of invasive fungal disease (IFD)…
  • 2018 American Transplant Congress

    Isavuconazole – The Real-World Use Experience

    H. Hassouna, V. Athans, K. Brizendine.

    Cleveland Clinic Foundation, Cleveland, OH.

    Isavuconazole (ISV) is a new triazole approved for treatment of mucormycosis and aspergillosis. Data on its effectiveness outside clinical trials and in patients receiving prior…
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