2019 American Transplant Congress
Bortezomib Attenuates the Progression of Epithelial to Mesenchymal Transition through Smurf1 Akt mTOR P70S6K Pathway in Rat Allograft Renal Interstitial Fibrosis Model
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: Our study was to detect the effects of Bortezomib and Smurf1 in the EMT and allograft renal interstitial fibrosis.*Methods: Biomarkers of EMT, as well…2019 American Transplant Congress
Cytomegalovirus (CMV) Infection Induces an Angiogenic Response through Hepatic Stellate Cells (HSCs) and Leads to Early Post-Transplant Liver Fibrosis (LF) and Poor Graft Survival
1Pathology, Baskent University, Ankara, Turkey, 2Transplantation, Baskent University, Ankara, Turkey
*Purpose: The ability of the CMV to infect the endothelial cells (ECs) is critical. CMV can increase EC adhesion, permeability, and create a pro-inflammatory environment…2019 American Transplant Congress
Initial Peritoneal sST2 Levels Are Associated with Peritoneal Failure and ST2 Blockade Mitigates TGF-β and High Glucose-Induced Peritoneal Fibrosis
*Purpose: Peritoneal fibrosis (PF) is an intractable complication which leads to peritoneal membrane failure in peritoneal dialysis (PD). The aim of this study was to…2019 American Transplant Congress
Occult Liver Graft Fibrosis Prior to Transplantation Influences Clinical Outcomes
Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Liver transplantation (LT) has become a standard therapy for the management of end-stage liver disease, while early allograft dysfunction (EAD) remains a serious problem.…2019 American Transplant Congress
Effect of Paricalcitol on Markers of Inflammation in De Novo Renal Transplant Recipients
*Purpose: Despite the reduction of systemic inflammation associated with receiving a functioning transplant, markers of inflammation may remain somewhat elevated in renal transplant recipients, and…2019 American Transplant Congress
Galectin-3 and Long-Term Graft Failure in Renal Transplant Recipients: A Prospective Cohort Study
*Purpose: Galectin-3 has been associated with renal fibrosis and decline of renal function. We aimed to determine the association of galectin-3 with long-term risk of…2019 American Transplant Congress
Long-term Impact of Antihypertensive Treatment and Tacrolimus Dose in Renal Allograft Recipients 5 Years Post-Transplantation
*Purpose: Inflammation and fibrosis after renal transplantation may be modulated by optimizing tacrolimus exposure, or by use of angiotensin-converting enzyme inhibitors (ACEi), or angiotensin receptor…2018 American Transplant Congress
Liver Stiffness Measurement, but Not Controlled Attenuation Parameter, is Increased in Deceased Liver Donors at the Time of Transplant Procurement
Background & Aims: The growing obesity rate and IV drug use in the USA presage a higher usage of liver allografts with NAFLD or active…2018 American Transplant Congress
Role of C1q-Binding Donor-Specific Anti-HLA Antibodies in Premature and Accelerated Kidney Allograft Interstitial Fibrosis
Paris Translational Research Center for Organ Transplantation, Paris, France.
The 2017 Banff meeting has focused on the importance of a precise diagnosis of IF/TA in kidney recipients by addressing specific etiological factors. Recent studies…2018 American Transplant Congress
Long Term Histologic Allograft Health is Preserved Despite Rejection during Protocolized Immunosuppression Withdrawal (ISW) in Stable Pediatric Liver Transplant Recipients
Background: Long term allograft health after rejection during ISW has not been previously assessed. We compare baseline and 4yr graft histology of 20 rejectors in…
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