2019 American Transplant Congress
Activation of Renal Fibroblasts by Anti- Major Histocompatibility Complex Antibody: A Missing Link in Allograft Fibrosis
*Purpose: Chronic antibody-mediated rejection (CAMR) is an important contributor to late kidney allograft loss, frequently accompanied by interstitial fibrosis and tubular atrophy. Donor-specific antibodies (DSA)…2019 American Transplant Congress
A Novel Apparatus Mimicking Hypertensive Kidney With Primary Cultured Human Kidney Cells Using Rotational Force: Application To In Vitro Drug Screening In Kidney Transplant Recipients
*Purpose: Cell culture is an essential part of the development for various medical technologies such as identifying the cause of the disease and developing new…2019 American Transplant Congress
Bortezomib Attenuates the Progression of Epithelial to Mesenchymal Transition through Smurf1 Akt mTOR P70S6K Pathway in Rat Allograft Renal Interstitial Fibrosis Model
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: Our study was to detect the effects of Bortezomib and Smurf1 in the EMT and allograft renal interstitial fibrosis.*Methods: Biomarkers of EMT, as well…2019 American Transplant Congress
Cytomegalovirus (CMV) Infection Induces an Angiogenic Response through Hepatic Stellate Cells (HSCs) and Leads to Early Post-Transplant Liver Fibrosis (LF) and Poor Graft Survival
1Pathology, Baskent University, Ankara, Turkey, 2Transplantation, Baskent University, Ankara, Turkey
*Purpose: The ability of the CMV to infect the endothelial cells (ECs) is critical. CMV can increase EC adhesion, permeability, and create a pro-inflammatory environment…2019 American Transplant Congress
Initial Peritoneal sST2 Levels Are Associated with Peritoneal Failure and ST2 Blockade Mitigates TGF-β and High Glucose-Induced Peritoneal Fibrosis
*Purpose: Peritoneal fibrosis (PF) is an intractable complication which leads to peritoneal membrane failure in peritoneal dialysis (PD). The aim of this study was to…2019 American Transplant Congress
Occult Liver Graft Fibrosis Prior to Transplantation Influences Clinical Outcomes
Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Liver transplantation (LT) has become a standard therapy for the management of end-stage liver disease, while early allograft dysfunction (EAD) remains a serious problem.…2019 American Transplant Congress
Effect of Paricalcitol on Markers of Inflammation in De Novo Renal Transplant Recipients
*Purpose: Despite the reduction of systemic inflammation associated with receiving a functioning transplant, markers of inflammation may remain somewhat elevated in renal transplant recipients, and…2019 American Transplant Congress
Galectin-3 and Long-Term Graft Failure in Renal Transplant Recipients: A Prospective Cohort Study
*Purpose: Galectin-3 has been associated with renal fibrosis and decline of renal function. We aimed to determine the association of galectin-3 with long-term risk of…2019 American Transplant Congress
Long-term Impact of Antihypertensive Treatment and Tacrolimus Dose in Renal Allograft Recipients 5 Years Post-Transplantation
*Purpose: Inflammation and fibrosis after renal transplantation may be modulated by optimizing tacrolimus exposure, or by use of angiotensin-converting enzyme inhibitors (ACEi), or angiotensin receptor…2019 American Transplant Congress
Clinical Implications of Serum Mac-2 Binding Protein in Regular Follow Up after Pediatric Living Donor Liver Transplantation
*Purpose: Pediatric living donor liver transplant (LDLT) patients sometimes develops graft fibrosis. They showed graft fibrosis even if their liver function tests were within normal…
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