2021 American Transplant Congress
Caspase-3 is a Predominant Regulator of Microvascular Dysfunction and Aki-ckd Transition Post Renal Ischemia-reperfusion Injury
CRCHUM, University of Montreal, Montreal, QC, Canada
*Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor for chronic renal failure. Caspase-3, an effector responsible for apoptosis execution, is activated within tubular epithelial…2021 American Transplant Congress
Identification and Validation of a Prognostic Index for Renal Allograft Survival Based on the Geo Database
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Chronic allograft injury (CAI) following kidney transplantation is still a threat to the allograft long-term survival. This study was designed to explore and analyze…2021 American Transplant Congress
Psmp is Discriminative for Chronic Active Antibody-Mediated Rejection and Predicts Graft Risk After Kidney Transplantation
Tianjin First Central Hospital, Tianjin, China
*Purpose: Chronic active antibody-mediated rejection (c-aABMR) is an intermediate process in the development of chronic antibody-mediated rejection (c-ABMR), a key problem in the long-term failure…2021 American Transplant Congress
The Role of Histone Acetylation/methylation Mediated Epigenetic Modifications in the Pathogenesis of Non-alcoholic Steatohepatitis-associated Liver Carcinogenesis
*Purpose: Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers and is characterized by an acquisition of multiple abnormal phenotypes driven by epigenetic…2021 American Transplant Congress
Perivenular Fibrosis After Pediatric Liver Transplant
*Purpose: Graft fibrosis is a concerning long-term complication after pediatric liver transplant (LT) and though perivenular (PV) fibrosis is common, its likelihood of progression and…2021 American Transplant Congress
Paired Surveillance Biopsies Over >4 Years from a Multi-Center Cohort of 78 Long-Term Pediatric Liver Transplant Recipients
*Purpose: Progressive liver fibrosis threatens graft and patient longevity for children after liver transplantation (LT). Previous studies are limited to single-center, cross-sectional analyses. To address…2020 American Transplant Congress
Exosomes Released from Natural Killer Cells Activation of Immune Responses: Role in Chronic Lung Allograft Dysfunction
Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Recent studies demonstrated natural killer (NK) cells can induce cytotoxicity both by direct cytotoxic mechanisms and antibody (Ab) dependent cytotoxicity; however its role in…2020 American Transplant Congress
The Therapeutic Potential of Human Liver-Derived Stem Cells Transplantation in Carbon Tetrachloride-Induced Rat Liver Cirrhotic Model
*Purpose: Cirrhosis is a long-term consequence of chronic hepatic injury and there are no effective treatment methods. Mesenchymal stem cells (MSCs) have been reported to…2020 American Transplant Congress
Mass-Spectrometry Based Discovery of Tubular Injury Marker in Chronic Kidney Disease
*Purpose: Renal tubular injury and interstitial fibrosis are inevitable processes in the progression of chronic kidney disease (CKD). The purpose of this study is to…2020 American Transplant Congress
Regulatory T Cell-Derived Amphiregulin Activates Fibroblasts to Promote Chronic Rejection after Heart Transplantation
*Purpose: Chronic rejection (CR) after organ transplantation (Tx) manifests as function-limiting allograft fibrosis and vasculopathy. Current immunosuppressants fail to prevent CR and insights into the…
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