2022 American Transplant Congress
Association of Circulating microRNAs with Fibrosis and Metabolic Outcomes in Chronic Pancreatitis Patients Undergoing Total Pancreatectomy with Islet Autotransplantation
*Purpose: In patients with Chronic Pancreatitis (CP), specific microRNAs (miRNA) were elevated in circulation before, during islet infusion and after TPIAT. We selected a panel…2022 American Transplant Congress
Angiotensin II-Regulated Proteins Production by Pulmonary Macrophages in Chronic Lung Allograft Dysfunction
*Purpose: Chronic lung allograft dysfunction (CLAD), characterized by fibrosis, is the most important cause of mortality after lung transplantation. CLAD mechanisms remain poorly understood and…2022 American Transplant Congress
Galectin-3 Expression in Autoimmune Hepatitis
*Purpose: Autoimmune hepatitis (AIH) is characterized by chronic inflammation in which healthy liver cells are targeted by one’s immune system. The persistent inflammatory milieu can…2022 American Transplant Congress
Molecular Characterization of Progressive Fibrosis in the Liver by Single-Nuclei RNA Sequencing
*Purpose: The prevalence of obesity is negatively affecting the availability of livers for transplantation. Non-alcoholic fatty liver disease (NAFLD) is associated with an increase in…2021 American Transplant Congress
Paired Surveillance Biopsies Over >4 Years from a Multi-Center Cohort of 78 Long-Term Pediatric Liver Transplant Recipients
*Purpose: Progressive liver fibrosis threatens graft and patient longevity for children after liver transplantation (LT). Previous studies are limited to single-center, cross-sectional analyses. To address…2021 American Transplant Congress
Liver Kinase B1 Knockdown Induces Platelet-Derived Growth Factor Receptor B Expression in Human Airway Epithelial Cells: A Potential Mechanism for Development of Fibrosis Leading to Chronic Lung Allograft Dysfunction
St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: The platelet-derived growth factor and its receptor (PDGFRb) signaling pathway can be activated by epithelial mesenchymal transition which facilitates fibrosis. It is not known…2021 American Transplant Congress
Non-Invasive Measurement of Transplant Kidney Fibrosis Using Photoacoustic Imaging
1St. Michael's Hospital, Toronto, ON, Canada, 2Ryerson University, Toronto, ON, Canada
*Purpose: The presence of donor kidney fibrosis adversely impacts transplant outcome. Biopsy remains the only method that can assess fibrosis, despite being subjected to sampling…2021 American Transplant Congress
Atg16l-Dependent Autophagy Attenuates Procession of Renal Interstitial Fibrosis in Chronic Renal Graft Dysfunction via Regulating Tumor Necrosis Factor Alpha (tnf-α) Induced Endmt
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Chronic renal graft dysfunction is characterized by inflammation, tubular injury, and interstitial fibrosis. We have confirmed that endothelial-mesenchymal transition (EndMT) was one of important…2021 American Transplant Congress
Molecular Assessment of Fibrosis and Steatohepatitis in the INTERLIVER Study
1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2., ., AB, Canada
*Purpose: We previously reported a molecular system for assessing rejection in liver transplants and recently expanded this system to assess injury. Fibrosis is associated with…2021 American Transplant Congress
Video Virtual Transplant Evaluation and Listing
*Purpose: Due to the COVID-19 pandemic, many hospitals suspended in person evaluations of kidney transplants during the March-April time period of 2020. State and local…
- « Previous Page
- 1
- 2
- 3
- 4
- 5
- …
- 17
- Next Page »