ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "Fibrosis"

  • 2017 American Transplant Congress

    RAS Inhibition Attenuates Urine Angiotensin II-Regulated Proteins Associated with Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients.

    Z. Mohammed-Ali,1 S. Reid,3 P. Yip,1 H. Cardinal,2 M.-J. Hébert,2 Y. Li,4 S. Kim,1,3,4 A. Konvalinka.1,3

    1University Health Network, Toronto, ON, Canada; 2Centre de Recherche du Centre Hospitalier de l'Université de Montréal - CRCHUM, Montréal, QC, Canada; 3Institute of Medical Science, University of Toronto, Toronto, ON, Canada; 4Institute of Health Policy, University of Toronto, Toronto, ON, Canada

    Angiotensin-II (AngII), the main effector of the renin-angiotensin system (RAS), can lead to interstitial fibrosis/ tubular atrophy (IFTA) in kidney transplant recipients, mainly through AT-1R…
  • 2017 American Transplant Congress

    TGF-β1 Induces Transplant Kidney Interstitial Fibrosis Through Endothelial-to-Mesenchymal Transition via TGF-β/Smad and Akt/mTOR/p70S6K Pathways.

    Z. Wang, Z. Han, J. Tao, R. Tan, M. Gu.

    Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

    Background: Chronic allograft dysfunction (CAD) induced by kidney interstitial fibrosis is the main cause of allograft failure in kidney transplantation. Studies suggested that endothelial-to-mesenchymal transition…
  • 2017 American Transplant Congress

    Mechanisms of Fibrosis in the Allograft Kidney: RNA-seq Based Analysis Using Formalin Fixed Biopsies.

    G. Zeng,2 L. Pan,1 Z. Lyu,1 Y. Huang,2 P. Randhawa.2

    1Department of Nephrology, Guangxi Medical University, Nanning, Guangxi, China; 2Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA

    Development of allograft fibrosis determines long term graft survival but our understanding of this important complication is incomplete. To gain further insight into this problem…
  • 2017 American Transplant Congress

    Impact of Antihypertensive (AHT) Choice and Advagraf® Dose on Interstitial Fibrosis/Tubular Atrophy (IF/TA) and IF/TA Progression in Renal Allografts 24 Months Post-Transplantation (Tx).

    S. Cockfield,1 D. Rush,2 S. Wilson,3 J. Howell,4 FKC-014 Study Group.

    1University of Alberta Hospital, Edmonton, AB, Canada; 2Health Sciences Centre, Winnipeg, MB, Canada; 3Astellas Pharma Global Development, Northbrook, IL; 4Astellas Pharma Global Development, Markham, ON, Canada

    IF/TA may be delayed using ACEi- or ARB-type AHTs, which target the renin-angiotensin system (RAS), as well as by optimizing tacrolimus (TAC) exposure. The effect…
  • 2017 American Transplant Congress

    Vimentin Regulates ß-Catenin Translocation During Epithelial to Mesenchymal Transition in Renal Fibrosis.

    R. Lopez-Soler, Z. Wang, A. Divanyan.

    Sugery, Section of Transplantation, Albany Medical Center, Albany, NY

    Introduction: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
  • 2017 American Transplant Congress

    Genomic Analysis of Gene Expression in Human Kidney Transplants Identifies Moxd1 as a Key Driver for Renal Fibrosis.

    C. Wei,1 M. Menon,1 W. Zhang,1 C. Woytovich,1 N. Philippe,1 J. He,1,2 B. Murphy,1 C. Wei.

    1Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY; 2Renal Section, James J Peter Veterans Affairs Medical Center, New York, NY

    Chronic allograft injury (CAI), characterized histologically by high chronic allograft dysfunction index (CADI) score on biopsy, is known to be a major determinant of graft…
  • 2017 American Transplant Congress

    DNA Hypermethylation Caused by Ischemia in Kidney Transplants Predicts Future Chronic Injury to the Allograft.

    L. Heylen,1,2,3,4 B. Thienpont,3,4 M. Naesens,1,2 J. Depreeuw,3,4 P. Busschaert,3,4 D. Kuypers,1,2 I. Jochmans,2,5 D. Monbaliu,2,5 J. Pirenne,2,5 D. Lambrechts,3,4 B. Sprangers.1,2

    1Nephrology, University Hospitals Leuven, Leuven, Belgium; 2Microbiology and Immunology, KU Leuven, Leuven, Belgium; 3Oncology, KU Leuven, Leuven, Belgium; 4VIB, Leuven, Belgium; 5Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium

    Study Purpose: DNA demethylation results from hydroxymethylation and is inhibited by hypoxia. We investigated whether ischemia during kidney transplantation induces DNA methylation changes of the…
  • 2017 American Transplant Congress

    Circulating Donor-Specific Anti-HLA Antibodies Accelerate the Progression of Interstitial Fibrosis in Kidney Allografts.

    C. Gosset, D. Viglietti, M. Rabant, E. Pillebout, A. Bouquegneau, J. Taupin, D. Glotz, C. Legendre, J. Duong Van-Huyen, A. Loupy, C. Lefaucheur.

    Paris Translational Research Center for Organ Transplantation, Paris, France

    Interstitial fibrosis represents a major cause of kidney allograft failure. Addressing the causes of accelerated ageing of kidney allografts represents an important challenge to improve…
  • 2017 American Transplant Congress

    Digital Image Analysis of Pediatric Liver Allograft Biopsies Correlates with METAVIR Fibrosis Score.

    R. Fischer,1 S. Foster,2 J. Daniel,1 R. Hendrickson,1 W. Andrews,1 A. Kats.1

    1Children's Mercy Hospital, Kansas City, MO; 2University of Kansas Medical Center, Kansas City, KS

    Background: Serial surveillance biopsies demonstrate post-transplant inflammation and fibrosis in long-surviving pediatric liver allografts. These changes can ultimately lead to cirrhosis and graft failure. However,…
  • 2017 American Transplant Congress

    Epigenetic Modifications in the Progression to Chronic Renal Allograft Injury.

    V. Bontha,1 D. Maluf,1 M. Dozmorov,2 K. Archer,3 L. Gallon,4 V. Mas.1

    1UVA, Charlottesville; 2VCU, Richmond; 3OSU, Columbus; 4NWU, Chicago

    Background: The renal allograft is exposed to a milieu of environmental/metabolic stimuli that trigger epigenetic modifications and thereby gene expression patterns which influence function and…
  • « Previous Page
  • 1
  • …
  • 10
  • 11
  • 12
  • 13
  • 14
  • …
  • 17
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences