2018 American Transplant Congress
Gr1– Macrophages Play Critical Roles in Liver Inflammation Resolution after IRI via Efferocytosis
Inflammation resolution is an integral part of liver ischemia reperfusion injury (IRI), which affects not only the severity of tissue damage, but more importantly its…2018 American Transplant Congress
Liver Biopsy Fibrosis Not Liver Imaging Predicts Survival after Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Hepatic dysfunction is common in patients with cardiomyopathy being evaluated for heart transplant (HT). ISHLT guidelines highlight the need for liver evaluation in patients…2018 American Transplant Congress
Cardiac MRI May Help to Determine When to Refer Heart Transplant Patients for Redo Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Small vessel coronary artery disease is known to cause fibrosis. However, it is not clear whether myocardial fibrosis detected on MRI is associated with…2018 American Transplant Congress
Krüppel-Like Factor 15 is a Key Suppressor of the Glomerular Epithelial Cell Fibrosis under Centrifugal Force Driven Pressure
Hypertension is known to be responsible for a reduction in the number of functional nephrons of glomeruli due to fibrosis, which develops into a chronic…2018 American Transplant Congress
Diagnostic Accuracy of Non-Invasive Test of Hepatic Fibrosis in Liver Transplant Recipients
Background & Aims: Hepatic fibrosis is an important predictor of liver- and non-liver related outcomes in patients with chronic liver disease (CLD) and liver transplantation…2018 American Transplant Congress
Multiparametric MRI for Assessment of Renal Transplant Fibrosis: A Pilot
Recanati Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Fibrosis in renal allografts confers risk of progression to allograft loss. The gold standard for evaluating renal fibrosis remains allograft biopsy, which is invasive, prone…2018 American Transplant Congress
Inflammation in Fibrotic Areas (i-IF/TA) Identifies a T Cell-Mediated Rejection Component of IF/TA with Poor Kidney Allograft Outcome
Paris Translational Research Center for Organ Transplantation, Paris, France.
Addressing the etiological heterogeneity of interstitial fibrosis in kidney allografts represents an important challenge to improve long-term transplant outcomes. We investigated the determinants, clinical and…2018 American Transplant Congress
Donor Acute Kidney Injury Does Not Affect Fibrosis on 1 Year Post-Transplant Kidney Biopsy
Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.
PurposeThe use of kidneys from deceased donors with acute kidney injury (AKI) at the time of donation is a potential method by which to expand…2018 American Transplant Congress
RNA-Seq Based Analysis of Renal Allograft Biopsies Reveals Key Mediators of Interstitial Fibrosis/Tubular Atrophy
Interstitial Fibrosis/Tubular Atrophy(IFTA) is the final common pathway of most progressive renal diseases and is a potent predictors of renal outcome in both native and…2018 American Transplant Congress
Upregulated IL-33 in Heart Transplants Modulates Local Myeloid Populations to Protect against Chronic Allograft Rejection
Purpose: Interleukin-33 (IL-33) is an “alarmin”, or a self-derived molecule that triggers pleotropic immune responses after release from damaged tissue. Yet, how IL-33 shapes alloresponses…
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