2021 American Transplant Congress
Expansion of Cd45ra-foxp3hi Activated Regulatory T Cells Predict Immune Tolerance in Patients with Combined Kidney and Bone Marrow Transplantation
*Purpose: Simultaneous transplantation of a solid organ and bone marrow from an identical donor is a possible means of achieving transplant tolerance. Here, we attempted…2021 American Transplant Congress
Immunosuppression is Not Associated with High-risk Immunologic Parameters in Transplant Recipients with the Sars-cov2 Virus
Medicine/Surgery, Columbia University Medical Center, New York, NY
*Purpose: The factors associated with severe COVID-19 disease in transplant patients are poorly understood. Despite concern that patients with weakened immune responses have increased risk…2021 American Transplant Congress
Renal Tubular-cell-specific Urinary Extracellular Vesicles: A Novel Biomarker for Diabetic Nephropathy After Kidney Transplantation
*Purpose: Diabetes(DM) is a leading cause of ESRD among renal transplant recipients(RTRs). However, the kinetics of diabetic nephropathy recurrence after renal transplantation(RT) remains unclear. Currently,…2021 American Transplant Congress
Characterization of Kidney Small Extracellular Vesicles Released During Normothermic Machine Perfusion
*Purpose: By characterizing and quantifying the dynamical release of kidney Extracellular Vesicles (EVs) during Normothermic Machine Perfusion (NMP), we aim to gain a better understanding…2021 American Transplant Congress
Imaging Flow Cytometry Reveals That Platelet-Sized Erythrocyte Fragments are Formed During Pig Organ Perfusion with Human Blood
*Purpose: Severe thrombocytopenia frequently occurs after xenotransplantation of porcine cells or organs, and when pig organs are perfused with human blood. We developed a flow…2021 American Transplant Congress
Donor T and NK Cells with a Special Tissue-Resident Memory Phenotype Migrate Into the Periphery of Lung Transplant Recipients – A Potential Feature for Tolerance Development
*Purpose: After lung transplantation (LuTx), a transient chimerism of donor cells exists in the blood of recipients due to the migration of lymphocytes from the…2021 American Transplant Congress
Donor Lymphocytes in Peripheral Blood of Patients After Lung Transplantation Comprise High Frequencies of Killer Cell Immunoglobulin-like Receptor-positive T and NK Cell Subsets
*Purpose: For end-stage lung diseases, lung transplantation (LuTx) is the only curative treatment option. However, acute and chronic rejections are major limitations. Thus, a deeper…2021 American Transplant Congress
T-Cell Exhaustion in EBV DNAemic Solid Organ Transplant Recipients
Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada
*Purpose: In transplant recipients, disease severity after infection with Epstein-Barr virus (EBV) may range from asymptomatic DNAemia to PTLD. Host factors likely play a key…2021 American Transplant Congress
Adenovirus-Specific T Cells for Steering of Immunosuppression After Pediatric Kidney Transplantation in the Randomized Controlled Ivist Trial
*Purpose: Pharmacokinetic monitoring alone is insufficient to estimate the intensity of immunosuppression after pediatric kidney transplantation (Tx). Levels of virus-specific T cells (Tvis) have been…2021 American Transplant Congress
T-Cell Responses in Solid Organ Transplant Recipients with SARS-CoV-2 Infection
University Health Network, Toronto, ON, Canada
*Purpose: Preliminary data suggest solid organ transplant (SOT) recipients may be at high-risk for developing severe COVID-19. This may be due in part to alterations…
- 1
- 2
- 3
- …
- 8
- Next Page »