ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Efficacy"

  • 2019 American Transplant Congress

    Effect of Induction Therapy on Outcomes of De Novo Renal Transplant Recipients Receiving Everolimus with Reduced-Dose Calcineurin Inhibitor: 24-Month Results from the TRANSFORM Study

    R. Oberbauer1, F. Vincenti1, O. Viklicky1, U. Huynh-Do1, D. Kim1, J. M. Cruzado1, Y. Qazi1, M. S. Kim1, P. Narvekar2, M. P. Hernandez Gutierrez2, P. Bernhardt2, D. Kuypers1

    1TRANSFORM Study Group, Basel, Switzerland, 2Novartis Pharma AG, Basel, Switzerland

    *Purpose: To assess the effect of induction therapy on efficacy and safety outcomes of de novo renal transplant recipients (RTxR) receiving everolimus with reduced calcineurin…
  • 2019 American Transplant Congress

    Improving the Organ Donation Process: Updated

    J. Yeh, M. P. Jarrett, L. Teperman

    Northwell Health, New Hyde Park, NY

    *Purpose: Due to the complexity of care that each ICU patient requires, the bedside nurse may miss the clinical trigger that would indicate an appropriate…
  • 2019 American Transplant Congress

    The Effect of a Novel Dosing Protocol for the De Novo Use of LCP Tacrolimus in Kidney Transplant Recipients Managed on a Steroid-Free Maintenance Immunosuppression Regimen

    R. Wolff1, A. Nasstrom1, C. Borscheid1, C. Martin1, A. Temelie1, R. Spong2, D. Keys2, T. B. Dunn3

    1School of Pharmacy, MHealth U of MN Medical Center-Fairview, Mpls, MN, 2Medicine, MHealth U of MN Medical Center-Fairview, Mpls, MN, 3Surgery, U of Pennsylvania, Phila, PA

    *Purpose: It is not known if an extended release formulation of tacrolimus (LCPT, Envarsus XR®) can be successfully dosed to achieve an early therapeutic trough…
  • 2019 American Transplant Congress

    Incidence of Cytomegalovirus in Moderate Risk Kidney Transplant Recipients Receiving Low Dose Valganciclovir

    T. Fallah1, A. Logan2, L. Beltran Garcia3, L. Bowman2

    1Hospital of the University of Pennsylvania, Philadelphia, PA, 2Tampa General Hospital, Tampa, FL, 3Florida Kidney Physicians, Tampa General Hospital, Tampa, FL

    *Purpose: Studies evaluating the efficacy of valganciclovir (VGC) at 450 mg daily versus 900 mg daily for the prevention of cytomegalovirus (CMV) in kidney transplant…
  • 2019 American Transplant Congress

    Implementation of Novel Machine-Learning Techniques to Tailor Donornet® Organ Offers to Center and Surgeon Preference

    A. C. Perez-Ortiz, N. Elias

    Transplant Center, Massachusetts General Hospital, Boston, MA

    *Purpose: Real-time communication regarding organ placement is critical. For this purpose, UNOS launched DonorNet®, a computerized allocation algorithm, to aid and facilitate organ placement. However,…
  • 2019 American Transplant Congress

    “Desens Light”: Single Center Experience Using Rituximab for High Immunologic Risk Kidney Transplant Recipients with Historic DSA

    A. Casillas-Abundis, A. Tambur, A. Shetty, C. D'Agostino, J. R. Leventhal

    Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: To evaluate the effectiveness of rituximab as induction therapy for pts undergoing kidney transplant (Tx) with historic DSA (hDSA) [Desens. Light].*Methods: 104 consecutive pts…
  • 2019 American Transplant Congress

    Blood Group Incompatible Living Donor Kidney Transplantation in Patients with End-Stage Kidney Disease Due to Diabetes Kidney Disease

    J. Uchida1, A. Kosoku1, K. Kabei1, S. Nishide1, H. Shimada1, K. Maeda2, Y. Yoshikawa3, T. Iwai1, N. Kuwabara1, T. Naganuma1, N. Kumada4, Y. Takemoto1, T. Nakatani1

    1Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, 2Nursing, Osaka City University Hospital, Osaka, Japan, 3Osaka City University, Osaka, Japan, 4Urology, Suita Municipal Hospital, Suita, Japan

    *Purpose: Diabetes is a growing public health problem, and diabetes kidney disease (DKD) is the most prevalent chronic kidney disease and the major cause of…
  • 2018 American Transplant Congress

    CTLA4-Ig and Bortezomib Successfully Reverses Established DSA Responses in Allograft-Sensitized Recipients

    D. Jain,1 J. Young,1 D. Yin,1 R. Pelletier,2 A. Chong.1

    1Department or Surgery, University of Chicago, Chicago, IL; 2Department of Surgery, Ohio State University, Columbus, OH.

    Background: Sensitized recipients have lower rates of transplantation and poorer outcomes. We and others have reported that the delayed administration of CTLA4-Ig can disrupt fully-established…
  • 2018 American Transplant Congress

    Primary Oral Vancomycin Prophylaxis Reduces the Incidence of Clostridium difficile Infection among Lung Transplant Recipients

    V. Bajrovic, K. Brizendine.

    Cleveland Clinic Foundation, Cleveland, OH.

    Purpose: To determine the efficacy of primary oral vancomycin prophylaxis in reducing the incidence of Clostridium difficile infection (CDI) in the early post-op period among…
  • 2018 American Transplant Congress

    Donor Derived Transmissions in 2016-2017: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)

    C. Wolfe, S. Tlusty, G. Vece, R. Bag, G. Berry, J. Bucio, L. Danziger-Isakov, D. Florescu, D. Goldberg, C. Ho, R. La Hoz, K. Lilly, M. Malinis, A. Mehta, M. Nalesnik, R. Sawyer, L. Strasfeld, P. Wood, N. Theodoropoulos, M. Michaels.

    DTAC, United Network for Organ Sharing, Richmond, VA.

    The DTAC evaluates unanticipated potential donor-derived transmission events (PDDTE), including mostly infections (I) & malignancies (M), to assess for likelihood of donor transmission. Reporting policy…
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