ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Efficacy"

  • 2019 American Transplant Congress

    Exploration of the Stanford Integrated Psychosocial Assessment for Transplant with Psychosocial and Medical Outcomes in Kidney/Kidney-Pancreas Transplant Recipients

    G. Chen1, C. Bell2, P. Loughhead1, B. Ibeche2, J. S. Bynon2, D. R. Hall2, A. M. De Golovine2, A. Edwards2, W. A. Dar2

    1Memorial Hermann Hospital, Houston, TX, 2The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX

    *Purpose: The Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) is a psychometric instrument designed to improve organ transplant patient selection. However, limited studies have been…
  • 2019 American Transplant Congress

    A Comparison of the Safety and Efficacy of Apixaban Use in Renal Transplant vs. Non-Renal Transplant Recipients

    T. Loosier, K. Gutierrez, A. James, A. Dodson

    University of Alabama at Birmingham Hospital, Birmingham, AL

    *Purpose: Background: Utilization of direct-acting oral anticoagulants has become a preferred method for chronic anticoagulation in patients with atrial fibrillation (AF) or venous thromboembolism (VTE).…
  • 2019 American Transplant Congress

    Early Use of Everolimus Plus Reduced Tacrolimus vs Standard Tacrolimus in De Novo Livertransplant Recipients: 12 Months Efficacy and Safety Data from HEPHAISTOS Study

    B. Nashan1, P. Schemmer1, H. Schlitt1, A. Pascher1, C. Klein1, U. Neumann1, I. Kroeger2, P. Wimmer2, F. Braun1

    1Study Group, Hephaistos, Germany, 2Novartis Pharma GmbH, Nuernberg, Germany

    *Purpose: The HEPHAISTOS study was set up to compare early use of everolimus [EVR] combined with reduced tacrolimus [rTAC] versus standard-dose tacrolimus [TAC-C) in de…
  • 2019 American Transplant Congress

    Treprostinil as a Bridge Therapy to Heart-Lung Transplants with Severe Pulmonary Arterial Hypertension

    C. Ju, Q. Lian, B. Wei, X. Xu, J. He, R. Chen

    State Key Lab of the Respiratory Disease, Guangzhou Institute of Respiratory Disease, Guangzhou, China

    *Purpose: Heart-lung transplants (HLTx) is the only one effective strategy for advanced pulmonary arterial hypertension (PAH) with refractory right heart failure. But limited availability of…
  • 2019 American Transplant Congress

    Antirejection Efficacy in De Novo Renal Transplant Recipients Receiving Everolimus with a Reduced-Exposure Calcineurin Inhibitor-Based Regimen: 24-Month Results from the TRANSFORM Study

    H. Tedesco Silva1, F. Citterio1, M. Henry1, T. R. Srinivas1, Y. Watarai1, S. Steinberg1, N. Basic-Jukic1, V. D. Garcia1, E. Mor1, V. R. Peddi1, P. Narvekar2, M. P. Hernandez Gutierrez2, P. Bernhardt2, J. Pascual1

    1TRANSFORM Study Group, Basel, Switzerland, 2Novartis Pharma AG, Basel, Switzerland

    *Purpose: To compare the antirejection efficacy outcomes of an everolimus+reduced-exposure CNI (EVR+rCNI) vs mycophenolic acid+standard-exposure CNI (MPA+sCNI) regimen in renal transplant recipients (RTxRs) from the…
  • 2019 American Transplant Congress

    Direct Oral Anticoagulants: An Evaluation of the Safety and Efficacy in Solid Organ Transplant Recipients

    T. Pasley, A. Logan, A. Brueckner, L. Bowman, A. Silverman, A. Rumore

    Tampa General Hospital, Tampa, FL

    *Purpose: The use of direct oral anticoagulants (DOACs) has not been fully adopted by the solid organ transplant (SOT) community due to factors including, fluctuating…
  • 2019 American Transplant Congress

    Effect of Everolimus with Reduced-Exposure Tacrolimus and Early Steroid Elimination in Pediatric Kidney Transplant Recipients: 36-Month Outcomes from the CRADLE Study

    H. Tedesco Silva1, R. Ettenger1, A. Bjerre1, M. Christian1, L. Dello Strologo1, S. D. Marks1, L. Pape1, P. Lopez2, M. Cousin2, P. Pandey2, B. Rauer2, M. Meier2, B. Tönshoff1

    1A2314 Study Group, Basel, Switzerland, 2Novartis Pharma AG, Basel, Switzerland

    *Purpose: To compare 36-month (M) efficacy and safety outcomes of an everolimus+reduced-exposure tacrolimus (EVR+rTAC)+steroids (CS) withdrawal regimen vs mycophenolate mofetil+standard-exposure TAC (MMF+sTAC)+CS in pediatric kidney…
  • 2019 American Transplant Congress

    Long-Term Efficacy of Direct-Acting Antiviral Agents

    J. Zhang, W. Sun, J. Lin, Y. Tian, L. Ma, L. Zhang, Y. Zhu

    Beijing Friendship Hospital, Capital Medical University, Beijing, China

    *Purpose: Long-term efficacy of direct-acting antiviral agents (DAAs) therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it in a Chinese cohort…
  • 2019 American Transplant Congress

    Burden of Respiratory Syncytial Disease among Hospitalized Immunocompromised Adults

    H. Nam, M. Ison

    Northwestern University Comprehensive Transplant Center, Chicago, IL

    *Purpose: Respiratory syncytial virus (RSV) is associated with significant mortality amongst hematopoietic stem cell transplant (HSCT) and lung transplant recipients. Although RSV is responsible for…
  • 2019 American Transplant Congress

    The Incidence of Fungal Infections in Pancreas Transplant Recipients in the Absence of Systemic Antifungal Prophylaxis

    S. Shaikh1, M. Cooper1, A. Nolan1, P. Abrams2

    1MedStar Georgetown University Hospital, Washington, DC, 2MedStar Gerogetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC

    *Purpose: Fungal infections after pancreas transplantation have been associated with morbidity and mortality, therefore transplant centers may elect to use systemic perioperative antifungal prophylaxis (ppx).…
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