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American Transplant Congress abstracts

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Articles tagged "Efficacy"

  • 2019 American Transplant Congress

    Antirejection Efficacy in De Novo Renal Transplant Recipients Receiving Everolimus with a Reduced-Exposure Calcineurin Inhibitor-Based Regimen: 24-Month Results from the TRANSFORM Study

    H. Tedesco Silva1, F. Citterio1, M. Henry1, T. R. Srinivas1, Y. Watarai1, S. Steinberg1, N. Basic-Jukic1, V. D. Garcia1, E. Mor1, V. R. Peddi1, P. Narvekar2, M. P. Hernandez Gutierrez2, P. Bernhardt2, J. Pascual1

    1TRANSFORM Study Group, Basel, Switzerland, 2Novartis Pharma AG, Basel, Switzerland

    *Purpose: To compare the antirejection efficacy outcomes of an everolimus+reduced-exposure CNI (EVR+rCNI) vs mycophenolic acid+standard-exposure CNI (MPA+sCNI) regimen in renal transplant recipients (RTxRs) from the…
  • 2019 American Transplant Congress

    Direct Oral Anticoagulants: An Evaluation of the Safety and Efficacy in Solid Organ Transplant Recipients

    T. Pasley, A. Logan, A. Brueckner, L. Bowman, A. Silverman, A. Rumore

    Tampa General Hospital, Tampa, FL

    *Purpose: The use of direct oral anticoagulants (DOACs) has not been fully adopted by the solid organ transplant (SOT) community due to factors including, fluctuating…
  • 2019 American Transplant Congress

    Effect of Everolimus with Reduced-Exposure Tacrolimus and Early Steroid Elimination in Pediatric Kidney Transplant Recipients: 36-Month Outcomes from the CRADLE Study

    H. Tedesco Silva1, R. Ettenger1, A. Bjerre1, M. Christian1, L. Dello Strologo1, S. D. Marks1, L. Pape1, P. Lopez2, M. Cousin2, P. Pandey2, B. Rauer2, M. Meier2, B. Tönshoff1

    1A2314 Study Group, Basel, Switzerland, 2Novartis Pharma AG, Basel, Switzerland

    *Purpose: To compare 36-month (M) efficacy and safety outcomes of an everolimus+reduced-exposure tacrolimus (EVR+rTAC)+steroids (CS) withdrawal regimen vs mycophenolate mofetil+standard-exposure TAC (MMF+sTAC)+CS in pediatric kidney…
  • 2019 American Transplant Congress

    Long-Term Efficacy of Direct-Acting Antiviral Agents

    J. Zhang, W. Sun, J. Lin, Y. Tian, L. Ma, L. Zhang, Y. Zhu

    Beijing Friendship Hospital, Capital Medical University, Beijing, China

    *Purpose: Long-term efficacy of direct-acting antiviral agents (DAAs) therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it in a Chinese cohort…
  • 2019 American Transplant Congress

    Burden of Respiratory Syncytial Disease among Hospitalized Immunocompromised Adults

    H. Nam, M. Ison

    Northwestern University Comprehensive Transplant Center, Chicago, IL

    *Purpose: Respiratory syncytial virus (RSV) is associated with significant mortality amongst hematopoietic stem cell transplant (HSCT) and lung transplant recipients. Although RSV is responsible for…
  • 2019 American Transplant Congress

    The Incidence of Fungal Infections in Pancreas Transplant Recipients in the Absence of Systemic Antifungal Prophylaxis

    S. Shaikh1, M. Cooper1, A. Nolan1, P. Abrams2

    1MedStar Georgetown University Hospital, Washington, DC, 2MedStar Gerogetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC

    *Purpose: Fungal infections after pancreas transplantation have been associated with morbidity and mortality, therefore transplant centers may elect to use systemic perioperative antifungal prophylaxis (ppx).…
  • 2019 American Transplant Congress

    Your Path to Transplant Education Increases Patients’ Transplant Knowledge, Attitudes, Informed Decision-Making, and Pursuit: An Randomized Controlled Trial

    A. D. Waterman1, Y. Cui2, J. D. Peipert3, J. L. Beaumont2, C. S. Anderson1, A. L. Paiva4, M. L. Robbins4

    1Division of Nephrology, University of California, Los Angeles, Los Angeles, CA, 2Terasaki Research Institute, Los Angeles, CA, 3Department of Medical Social Sciences, Northwestern University, Chicago, IL, 4Department of Psychology, University of Rhode Island, Kingston, RI

    *Purpose: Most kidney transplant (KT) education is “one-size-fits-all” where patients’ unique gaps in knowledge, challenges, and level of readiness to pursue KT and living donor…
  • 2019 American Transplant Congress

    Optimizing Patient Blood Management in Simultaneous Kidney and Pancreas Transplantation

    D. P. Al-Adra, J. Odorico, D. Kaufman, R. Redfield, J. P. Connor

    University of Wisconsin, Madison, WI

    *Purpose: To identify a post-operative hematocrit (Hct) target for patients recovering from simultaneous kidney and pancreas (SPK) transplant and pancreas transplant alone (PTA) that is…
  • 2019 American Transplant Congress

    The Collaborative Improvement and Innovation Network (COIIN): Impact on Deceased Donor Transplant Rates and Offer Acceptance Practices

    A. Wey1, S. Gustafson1, B. Carrico2, J. Foutz2, K. Sisaithong3, M. McBride2, D. Klassen2, D. Klassen2, N. Salkowski1, B. Kasiske1, A. Israni1, J. Snyder1

    1SRTR, Minneapolis, MN, 2OPTN, Richmond, VA, 3OPTN, Minneapolis, MN

    *Purpose: The Organ Procurement and Transplantation Network (OPTN) completed the Collaborative Improvement and Innovation Network (COIIN), a study to increase kidney transplants by reducing risk…
  • 2019 American Transplant Congress

    A Comparison of the BAR, DRM, DRI, sRRI, ET-DRI, D-MELD and SOFT Score to Predict Outcome after Liver Transplantation in the SRTR Database

    J. D. de Boer1, H. Putter2, J. J. Blok1, I. P. Alwayn1, B. Van Hoek3, A. E. Braat1

    1Transplant Center, Leiden University Medical Center, Leiden, Netherlands, 2Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands, 3Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: Several risk models have been developed to predict outcome after liver transplantation (LT) in the last decade. This study analyzes the ability of these…
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