Articles tagged "Efficacy"

2015 American Transplant Congress
Efficacy and Safety of Once-Daily Everolimus With Minimized Once-Daily Tacrolimus After Liver Transplantation
P. De Simone,¹ P. Carrai,¹ L. Coletti,¹ A. Precisi,² D. Campani,³ F. Filipponi.¹
¹Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospital, Pisa, Italy; ²Laboratory, University of Pisa Medical School Hospital, Pisa, Italy; ³Pathology, University of Pisa Medical School Hospital, Pisa, Italy.
Background: The everolimus (EVR) pharmacokinetic profile allows for its once daily (OD) administration. We tested the efficacy and safety of a combination schedule of OD-EVR…
2015 American Transplant Congress
Effectiveness of Neovascularization Surrounding Engrafted Islets by Matrigel With Additional Growth Factors in Intramuscular Islet Transplantation
G. Yoshimatsu,^1,2 N. Sakata,² H. Tsuchiya,² M. Takita,³ M. Levy,³ B. Naziruddin,³ M. Unno.²
¹Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; ²Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan; ³Baylor Annette C. and Harold C. Simmons Transplant Institute, Dallas, TX.
Introduction: Intramuscular islet transplantation is one of the promising transplant sites because of safety, easy accessibility and less invasive procedure. However the efficacy of the…
2015 American Transplant Congress
The Impact of the Arterial Reconstructions On the Living Donor Kidney Graft
T. Hiramitsu, K. Futamura, M. Okada, K. Ito, M. Tsujita, N. Goto, S. Narumi, Y. Watarai.
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan.
BackgroundProcurement side of living donor kidney is decided according to the kidney function. We procure the kidney with lower function for the remaining donor kidney…
2015 American Transplant Congress
Assessment of Bleeding and Thrombosis in Responders and Initial Non-Responders to Aspirin After Continuous-Flow Left Ventricular Assist Device Placement
C. Floroff, K. Rieger, T. Veasey, S. Strout, H. Meadows, M. Stroud, J. Toole, M. Brisco, J. Cook, J. Lazarchick, W. Uber.
Medical University of South Carolina, Charleston, SC.
Purpose: This study evaluates bleeding and thrombosis following left ventricular assist device (LVAD) placement using platelet inhibition monitoring to determine responders to standard aspirin dosing…
2015 American Transplant Congress
Comparison of Efficacy and Renal Function in KidneyTransplant Recipients Receiving Tacrolimus (TAC)-Based Immunosuppressive Regimens in Combination With Everolimus (EVR) or Mycophenolate (MPA)
A. Ferreira,¹ C. Felipe,¹ P. Ueno,¹ P. Hannun,¹ P. Ruppel,¹ T. Sandes-Freitas,¹ H. Proença,³ J. Medina- Pestana,¹ H. Tedesco-Silva.¹
¹Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; ²Pathology, UNIFESP, Sao Paulo, Brazil.
Introduction: Acute rejection and renal function are associated with long-term renal allograft survival. We evaluated these outcomes in patients receiving reduced TAC exposure combined with…
2015 American Transplant Congress
Treatment With Everolimus and Reduced-Exposure Cyclosporine Is Efficacious in De Novo Renal Transplant Recipients at Increased Risk for Efficacy Failure: Post-Hoc Analysis from the A2309 Study
M. Carmellini,¹ V. Garcia,¹ Z. Wong,² M. Vergara,² C. Escrig,² G. Russ.¹
¹For the A2309 Study Group, Italy; ²Novartis, Basel, Switzerland.
Purpose: Data is limited on the effect of everolimus (EVR) based regimens in renal transplant recipients (RTxR) who are at increased risk for rejection and…
2015 American Transplant Congress
Factors Affecting Efficacy Outcomes at 12 and 24-Months After Kidney Transplantation in Patients from the A2309 Study
C. Escrig,¹ G. Colussi,² R. Roland,² M. Vergara,³ Z. Wang.³
¹Novartis, Basel, Switzerland; ²A2309 Study Group, Basel, Switzerland; ³Novartis, East Hanover, NJ.
Purpose: Efficacy outcomes post-transplantation are influenced by donor and recipient variables and interactions between them. Here, we present data from a multivariate analysis of risk…