ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Efficacy"

  • 2016 American Transplant Congress

    Reduced CMV Infection Using Single Low-Dose of Rabbit Anti-Thymocyte Globulin in Kidney Transplanted Recipients.

    M. Paula, C. Felipe, M. Cristelli, P. Orlandi, L. Viana, G. Basso, P. Carvalho, C. Montenegro, A. Lima, I. Pietrobom, H. Tedesco-Silva, J. Medina-Pestana.

    Hospital do Rim - UNIFESP, Sao Paulo, Brazil.

    BACKGROUND: Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality after solid organ transplantation and the historic incidence of our institution was 77%. Aiming…
  • 2016 American Transplant Congress

    Safety, Efficacy, and Cost Saving Potential of Various Weight-Based Dosing for Thymoglobulin Induction Therapy in Kidney Transplant Recipients.

    R. Miller,1 H. Meadows,1 S. Strout,1 T. Veasey,1 A. Mardis,1 J. Fleming,1 C. Mardis,1 N. Pilch,1 K. Chavin,2 D. Taber.2

    1Department of Pharmacy, Medical University of South Carolina, Charleston, SC; 2Department of Surgery, Medical University of South Carolina, Charleston, SC.

    Introduction: There are limited data assessing the appropriate weight to use when dosing Thymoglobulin for induction therapy. The aim of this study is to assess…
  • 2016 American Transplant Congress

    A Prospective Randomized, Comparative Trial of High-Dose Mizoribine versus Mycophenolate Mofetil in Combination with Tacrolimus and Basiliximab for Living Donor Renal Transplantation: A Multi-Center Trial.

    H. Ishida,1 K. Tanabe,1 S. Takahara,2 N. Amada,3 K. Takahashi,4 H. Toma.5

    1Urology, Tokyo Women's Medical University Hospital, Tokyo, Japan; 2Advanced Technology for Transplantation, Osaka University, Osaka, Japan; 3Surgery, JCHO Sendai Hospital, Sendai, Japan; 4Niigata Organ Transplant Foundation, Niigata, Japan; 5Urology, Toda Chuo Hospital, Toda, Saitama, Japan.

    PURPOSE: To compare the clinical outcomes of mizoribine (MZR; 12 mg/kg/day) and mycophenolate mofetil (MMF; 2000 mg/day) in combination with tacrolimus (FK), basiliximab (SIM), and…
  • 2016 American Transplant Congress

    Novel Effect of miR-26a:Mdm2:p53 Pathway on Mouse Liver Regeneration.

    J. Zhou, W. Ju, X. Yuan, X. Jiao, D. Wang, X. Zhu, X. He.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    BACKGROUND: The deficiency of liver regeneration needs to be addressed in the fields of liver surgery, split liver transplantation and living donor liver transplantation. Researches…
  • 2016 American Transplant Congress

    ESM1 Gene Promotes Hepatocyte Proliferation Through NF-κB Signal Pathway.

    J. Zhou, W. Ju, X. Jiao, X. Zhu, X. He.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    BACKGROUND: Effective and timely liver regeneration is pivotal in the prevention of fetal small-for-size syndrome after living donor liver transplantation or split liver transplantation. Our…
  • 2016 American Transplant Congress

    Chimeric Cell Transplantation for Treatment of Duchenne Muscular Dystrophy: A Preliminary Report.

    E. Szilagyi, E. Bryndza Tfaily, J. Cwykiel, M. Siemionow.

    Orthopaedic Surgery, University of Illinois at Chicago, Chicago.

    Background: Transplant of Chimeric Cells, created via ex vivo fusion of donor and recipient cells, represents a promising cell therapy option in the field of…
  • 2016 American Transplant Congress

    Human Epineural Allograft Conduits Supported with Mesenchymal Stem Cells Enhance Peripheral Nerve Regeneration: A Preliminary Report.

    M. Siemionow, M. Strojny, W. Malewski, J. Cwykiel, M. Cyran.

    Department of Orthopaedics, University of Illinois at Chicago, Chicago, IL.

    PURPOSE: Due to the limitations of current surgical methods of long nerve defect repair, new therapeutic approaches are needed to enhance nerve regeneration. Nerve allografts…
  • 2016 American Transplant Congress

    Schisandra Sphenanthera Extract Facilitates Anti-Tuberculosis Treatment Post Renal Transplantation Through Increasing Bioavailability of Tacrolimus.

    R. Deng,1 L. Zhang,1 L. Liu,1 H. Fu,2 J. Li,1 Q. Fu,1 C. Wang.1

    1Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; 2Infectious Medicine Department, Guangzhou Infectious Disease Hospital, Guangzhou, China.

    Background: Hepatoprotective agent Schisandra sphenanthera extract (SchE) facilitates rifampicin-containing anti-tuberculosis (TB) chemotherapy by stabilizing the Tacrolimus (FK506) blood concentration through increasing the oral bioavailability, which…
  • 2016 American Transplant Congress

    Where Are the KDPI 0-20% Kidneys Going in the New KAS? A Major Allocation Shift.

    M. Aeder,1 N. Turgeon,2 A. Kucheryavaya,3 D. Stewart.3

    1Univ Hosp Case Med Ctr, Cleveland, OH; 2Emory Univ, Atlanta, GA; 3UNOS, Richmond, VA.

    The introduction of KAS in December 2014 marked an effort to incorporate a longevity metrics into deceased organ allocation by prioritizing retrieved kidneys with the…
  • 2016 American Transplant Congress

    Belatacept Conversion in Adult Kidney Transplant Recipients for Cause: A Single Center Observational Cohort.

    M. Savic,1 M. Cruz,2 A. Rossi,1 J. Vella.1

    1Maine Transplant Program, Maine Medical Center, Portland, ME; 2University of Connecticut, Storrs, CT.

    Background: Calcineurin inhibition (CNI) is the single most effective strategy to prevent allograft rejection however tolerability is limited by toxicity. To date, alternate strategies have…
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