2022 American Transplant Congress
No Grapefruit Juice Interaction with Tacrolimus LCP in Kidney Transplant Recipients
*Purpose: It is well known that grapefruit juice (GFJ) interacts with many medications through an intestinal CYP3A-mediated interaction that does not involve hepatic CYP3A and…2021 American Transplant Congress
Pilot Evaluation of Prognosis After Liver Transplantation in Patients with a History of Hepatocellular Carcinoma and Pd-1 Inhibition
*Purpose: The successful applications of programmed death protein-1 (PD-1) inhibitors in cancer therapy has led to an expanding use of immunotherapy in oncolog Liver transplantation…2021 American Transplant Congress
A Retrospective Analysis of the Safety and Efficacy of Apixaban After Lung Transplant
*Purpose: Atrial arrhythmias and venous thromboembolism (VTE) are common after lung transplant. While direct acting oral anticoagulants (DOACs) have become anticoagulants of choice in atrial…2021 American Transplant Congress
Management of Drug Interactions During Protocolized Implementation of Posaconazole Immediately Post Heart Transplant
Massachusetts General Hospital, Boston, MA
*Purpose: Posaconazole (POSA) is a strong CYP3A4 inhibitor known to increase tacrolimus exposure by up to 4-fold. Initiation requires empiric tacrolimus dose adjustment and close…2021 American Transplant Congress
Evaluate the Effect of Cresemba (isavuconazonium Sulfate) Capsule and Noxafil (posaconazole) Delayed Release Tablets on Tacrolimus Dose to Concentration (D/C) Ratios in Lung Transplant Recipients
*Purpose: Evaluate the effect of Cresemba (isavuconazonium sulfate) capsule and Noxafil (posaconazole) delayed release tablet on tacrolimus dose to concentration (D/C) ratio in lung transplant.*Methods:…2021 American Transplant Congress
Managing the Significant Drug-Drug Interaction Between Tacrolimus and Letermovir in Solid Organ Transplant Recipients
NewYork-Presbyterian Hospital, New York, NY
*Purpose: Letermovir does not appear to share cross-resistance with ganciclovir and is not associated with nephrotoxicity or myelosuppressive effects, making it an attractive option for…2021 American Transplant Congress
Are Tacrolimus Concentrations Reduced with Direct-acting Antiviral Administration in Transplant Recipients?
Pharmacy, Penn State Health Hershey Medical Center, Hershey, PA
*Purpose: To evaluate the effects of direct-acting antivirals (DAAs) on tacrolimus trough concentrations and clinical outcome and to assess the need for a priori dose…2021 American Transplant Congress
Iatrogenic Sodium Exposure in Hospitalized Patients with Liver Disease
*Purpose: Numerous medications administered in the hospital setting may contain hidden/additional amounts of sodium in the drug itself and via intravenous (IV) diluents or admixtures.…2021 American Transplant Congress
Reduction in Medication Errors at Discharge in the Transplant Population via Use of Novel Pharmacist / Nursing Dual Check System
Hospital of the University of Pennsylvania, Philadelphia, PA
*Purpose: Medication errors are of great concern due to the risk for patient and allograft injury. The aim of this study was to evaluate the…2021 American Transplant Congress
Influence of Immunosuppressive Drug Trough Levels on Nk Cells in Liver Transplantation
*Purpose: Natural killer (NK) cells are enriched in lymphocytes within the liver and are considered to be main regulators of liver transplantation (LT) rejection and…
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