2022 American Transplant Congress
Artificial Intelligence Based Dosing of Tacrolimus in Liver Transplantation: Prospective, Randomized Phase 2 Trial
*Purpose: Inter- and intra-individual variability in calcineurin dose requirements necessitates empirical clinician-titrated dosing that frequently results in deviation from target ranges, particularly during the critical…2022 American Transplant Congress
Use of Dd-cfdna to Guide Tapering of Immunosuppression Therapy in Kidney Transplant Recipients
1Victoria Kidney and Dialysis Associates, Victoria, TX, 2Natera, Inc., Austin, TX
*Purpose: Continuous administration of immunosuppressive therapy (IST) is required to avoid allograft rejection in transplant recipients. However, these therapeutic interventions can lead to significant side…2022 American Transplant Congress
Incidence of Dapsone-Induced Methemoglobinemia in Solid Organ Transplant Recipients
*Purpose: The purpose of this study was to determine the incidence of dapsone-induced methemoglobinemia in solid organ transplant recipients.*Methods: This was a single-center retrospective cohort…2022 American Transplant Congress
Safety and Efficacy of Darbepoetin Alfa Dosing Strategies in Renal Transplant Recipients
Baylor University Medical Center, Dallas, TX
*Purpose: Post-transplant anemia (PTA) is a common phenomenon in renal transplant recipients (RTR). There are currently no consensus guidelines for PTA, however patients are commonly…2022 American Transplant Congress
Kidney Transplant Recipients with Diabetic Mellitus Demand Larger Doses of Mycophenolate Mofetil
Kidney transplant surgery and Urology, Sapporo City General Hospital, Sapporo, Japan
*Purpose: To monitor blood concentration of immunosuppressants, therapeutic drug monitoring (TDM) is required at any point after kidney transplantation (KT) to prevent kidney graft from…2021 American Transplant Congress
Modeling of Alternative Weight-Based Dosing Strategies of LCP-Tacrolimus in De Novo Kidney Transplant Patients
*Purpose: LCP-tacrolimus (LCPT; Envarsus XR®) is a modified-release once-daily formulation approved for prophylaxis of organ rejection in de novo kidney transplant patients in combination with…2021 American Transplant Congress
Anterior Rectus Sheath versus Standard Gibson Approach to Kidney Transplantation: A Randomized Double-blinded Controlled Trial
Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Purpose: The anterior rectus sheath (ARS) approach to kidney transplantation (KT) involves a small skin incision to incise the ARS and medially retract rectus…2021 American Transplant Congress
Tacrolimus Dose Requirements in Lung Transplant Recipients on Systemic Azole Antifungals: The Influence of Race and Transplant Indication
*Purpose: CYP3A5 polymorphisms, drug interactions, and alterations in gastric absorption impact tacrolimus metabolism. This is important for those at higher risk of expressing these factors,…2021 American Transplant Congress
Impact of the Transplant Clinical Pharmacist in an Outpatient Transplant Clinic
1Emory University Hospital, Atlanta, GA, 2Emory Transplant Center, Atlanta, GA
*Purpose: Pharmacist involvement in the outpatient transplant clinic setting has been correlated with improved patient outcomes in single organ cohort studies. Direct clinical pharmacist involvement…2021 American Transplant Congress
Letermovir Prophylaxis in Solid Organ Transplant – CMV Breakthrough and Tacrolimus Drug Interaction
*Purpose: Valganciclovir is the preferred drug for cytomegalovirus (CMV) prophylaxis in solid organ transplantation. A limitation to its use is profound myelosuppression. Letermovir is a…
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