2022 American Transplant Congress
The Role of Gut Microbiota in Tacrolimus Blood Level Fluctuation, Time in Therapeutic Range and AlloSure Donor Derived Cell-Free DNA, Controlling for CYP3A5
1George Mason University, Arlington, VA, 2George Washington University Hospital, Washington, DC
*Purpose: High tacrolimus variability (TV), low time in therapeutic range (TTR) and high percentage of donor derived cell-free DNA (dd-cfDNA) are associated with acute kidney…2022 American Transplant Congress
Impact of African American Race on Lcp-Tac Dosing and Clinical Outcomes
Medical University of South Carolina, Charleston, SC
*Purpose: The goal of this study was to assess the impact of African American (AA) race on the conversion ratio from Tac-IR to LCP-Tac, while…2022 American Transplant Congress
XR Tacrolimus Dosing By Ideal Body Weight Reduces Incidence Of Early Supratherapeutic Tacrolimus Concentrations
Pharmacy, NewYork-Presbyterian Hospital, New York, NY
*Purpose: At our center, the use of de novo Envarsus XR® (extended-release [XR] tacrolimus) dosed at 0.12 mg/kg is standard of care in adult kidney…2022 American Transplant Congress
The Role Of Gut Microbiome In Optimum Dose Selection Of Tacrolimus For Kidney Transplant Recipients
1George Mason University, Arlington, VA, 2George Washington University Hospital, Washington, DC
*Purpose: This study aims to validate and apply a personalized optimal dose selection model for Tacrolimus (Tac) for kidney transplant recipients at the George Washington…2022 American Transplant Congress
Thymoglobulin Induction Protocol: Quality Improvement Project via Clinical Audit
*Purpose: The aim of our study was to analyze the adequacy of the thymoglobulin (rATG) induction protocol for the expanding and higher complexity kidney transplant…2022 American Transplant Congress
Post-Kidney Transplant Valacyclovir or Valganciclovir for EBV Prophylaxis: A Randomized Controlled Trial
*Purpose: EBV viremia post-kidney transplant (KTx) has no proven prophylaxis.*Methods: In this randomized, open-label trial [NCT01329185], adult and pediatric recipients were randomly assigned (1:1) to…2022 American Transplant Congress
Optimal Dose of Anti-Thymocyte Globulin to Improve Allograft and Patient Survival After Kidney Transplantation: Analysis from Korean Organ Transplantation Registry Data
Surgery, Asan Medical Center, Seoul, Seoul, Korea, Republic of
*Purpose: The optimal dose of anti-thymocyte globulin (ATG) as an induction regimen in Asian kidney recipients is unclear.*Methods: Using Korean Organ Transplantation Registry database, we…2022 American Transplant Congress
Reduction of Rabbit Anti-Thymocyte Globulin Dosing for Induction of Kidney Transplant During the COVID-19 Pandemic
*Purpose: Rabbit anti-thymocyte globulin (rATG) is a polyclonal antibody utilized for induction immunosuppression in high immunologic risk kidney transplant recipients. However, the optimal total dose…2022 American Transplant Congress
Real-Life Tacrolimus Levels Are Associated with Biopsy-Proven Acute Rejection After the First Year Post-Kidney Transplantation
*Purpose: Evidence to recommend specific target concentrations for immunosuppression beyond the first year of kidney transplantation (KT) is limited. We correlated real-life exposure data of…2022 American Transplant Congress
Conversion of Tacrolimus Immediate Release to LCP Tacrolimus in Obese Kidney Transplant Recipients
*Purpose: Data describing the safety, efficacy and conversion ratio of tacrolimus immediate release (IR) to LCP-tacrolimus (LCP) in obese patients (BMI > 30) is lacking.…
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