ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Dosage"

  • 2022 American Transplant Congress

    Use of Dd-cfdna to Guide Tapering of Immunosuppression Therapy in Kidney Transplant Recipients

    G. Osuchukwu1, A. Trevino1, L. Beretich2, S. McCormick2, N. Kaur2, R. White2, P. Gauthier2

    1Victoria Kidney and Dialysis Associates, Victoria, TX, 2Natera, Inc., Austin, TX

    *Purpose: Continuous administration of immunosuppressive therapy (IST) is required to avoid allograft rejection in transplant recipients. However, these therapeutic interventions can lead to significant side…
  • 2022 American Transplant Congress

    Incidence of Dapsone-Induced Methemoglobinemia in Solid Organ Transplant Recipients

    D. Quan1, R. Gordon1, J. Lee1, D. Khoshabafard2, A. Han1

    1Pharmacy, UCSF Medical Center, San Francisco, CA, 2Clinical Phamacy, UCSF School of Pharmacy, San Francisco, CA

    *Purpose: The purpose of this study was to determine the incidence of dapsone-induced methemoglobinemia in solid organ transplant recipients.*Methods: This was a single-center retrospective cohort…
  • 2022 American Transplant Congress

    Safety and Efficacy of Darbepoetin Alfa Dosing Strategies in Renal Transplant Recipients

    J. A. Solis, A. Dao, T. Sam, T. Ma, A. F. Yango, B. V. Fischbach, N. Wilson

    Baylor University Medical Center, Dallas, TX

    *Purpose: Post-transplant anemia (PTA) is a common phenomenon in renal transplant recipients (RTR). There are currently no consensus guidelines for PTA, however patients are commonly…
  • 2022 American Transplant Congress

    Kidney Transplant Recipients with Diabetic Mellitus Demand Larger Doses of Mycophenolate Mofetil

    D. Takamoto, H. Sasaki, S. Harada, Y. Takada, H. Harada, T. Tsujimoto

    Kidney transplant surgery and Urology, Sapporo City General Hospital, Sapporo, Japan

    *Purpose: To monitor blood concentration of immunosuppressants, therapeutic drug monitoring (TDM) is required at any point after kidney transplantation (KT) to prevent kidney graft from…
  • 2022 American Transplant Congress

    The Role of Gut Microbiota in Tacrolimus Blood Level Fluctuation, Time in Therapeutic Range and AlloSure Donor Derived Cell-Free DNA, Controlling for CYP3A5

    M. Nayebpour1, N. Koizumi1, J. Melancon2, M. Hasan2

    1George Mason University, Arlington, VA, 2George Washington University Hospital, Washington, DC

    *Purpose: High tacrolimus variability (TV), low time in therapeutic range (TTR) and high percentage of donor derived cell-free DNA (dd-cfDNA) are associated with acute kidney…
  • 2022 American Transplant Congress

    Impact of African American Race on Lcp-Tac Dosing and Clinical Outcomes

    T. Sprague, F. Bartlett, J. Newman, S. Patel, N. Rao, E. Andrande, V. Rohan, D. Dubay, M. Casey, D. Taber

    Medical University of South Carolina, Charleston, SC

    *Purpose: The goal of this study was to assess the impact of African American (AA) race on the conversion ratio from Tac-IR to LCP-Tac, while…
  • 2022 American Transplant Congress

    XR Tacrolimus Dosing By Ideal Body Weight Reduces Incidence Of Early Supratherapeutic Tacrolimus Concentrations

    G. Codispodo, J. Hedvat, D. Salerno, N. Lange

    Pharmacy, NewYork-Presbyterian Hospital, New York, NY

    *Purpose: At our center, the use of de novo Envarsus XR® (extended-release [XR] tacrolimus) dosed at 0.12 mg/kg is standard of care in adult kidney…
  • 2022 American Transplant Congress

    The Role Of Gut Microbiome In Optimum Dose Selection Of Tacrolimus For Kidney Transplant Recipients

    M. Nayebpour1, N. Koizumi1, J. Melancon2

    1George Mason University, Arlington, VA, 2George Washington University Hospital, Washington, DC

    *Purpose: This study aims to validate and apply a personalized optimal dose selection model for Tacrolimus (Tac) for kidney transplant recipients at the George Washington…
  • 2022 American Transplant Congress

    Thymoglobulin Induction Protocol: Quality Improvement Project via Clinical Audit

    S. Mouawad1, J. Dann1, A. Kumar2, S. Rao3

    1University of Virginia Health System, Charlottesville, VA, 2Nephrology, University of Virginia, Charlottesville, VA, 3University of Virginia, Charlottesville, VA

    *Purpose: The aim of our study was to analyze the adequacy of the thymoglobulin (rATG) induction protocol for the expanding and higher complexity kidney transplant…
  • 2022 American Transplant Congress

    Post-Kidney Transplant Valacyclovir or Valganciclovir for EBV Prophylaxis: A Randomized Controlled Trial

    P. S. Verghese1, A. Matas2, S. Chinnakotla2, M. Evans3, H. Balfour Jr4

    1Pediatric Nephrology, Northwestern University, Feinberg School of Medicine, Minneapolis, MN, 2Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Biostatistics, University of Minnesota, Minneapolis, MN, 4Lab Medicine & Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: EBV viremia post-kidney transplant (KTx) has no proven prophylaxis.*Methods: In this randomized, open-label trial [NCT01329185], adult and pediatric recipients were randomly assigned (1:1) to…
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