2018 American Transplant Congress
A Review of Pediatric Drug Development Programs and FDA Labeling for Immunosuppressive Drugs in Organ Transplant Patients
The development of drugs for organ transplantation spanned the time before and after pediatric regulatory requirements under the Best Pharmaceuticals for Children Act (BPCA) and…2018 American Transplant Congress
Does One Size Fit All? Implementing a Protocolized Ambulatory Tacrolimus Dosing Strategy in a Predominantly African American Renal Transplant Population
Medical University of South Carolina, Charleston, SC.
Introduction: African American (AA) KTx recipients have significant tacrolimus (FK) inter patient variability making protocolized dosage adjustment challenging. We sought to evaluate the efficacy &…2018 American Transplant Congress
Evaluation of Tacrolimus Extended-Release in African American Renal Transplant Recipients
University of Maryland, Baltimore.
Purpose: Limited data exists to guide appropriate dosing strategies for novel tacrolimus formulations, such as tacrolimus XL (Astagraf XL). This is especially true in the…2018 American Transplant Congress
Itraconazole Prophylaxis, Trough Concentration, and Identification of Fungal Pathogens in Lung Transplant
Cleveland Clinic Foundation, Cleveland, OH.
Studies of prophylactic itraconazole (ITR) in lung transplant recipients (LTR) are lacking. Our purpose was to evaluate LTR who received ITR prophylaxis and the association…2018 American Transplant Congress
Use of Surgically Placed Transversus Abdominis Plane (TAP) Block Catheter with Local Anesthetic Infusion in Renal Transplantation
BackgroundRenal transplant recipients have limitations in pain management, given the nephrotoxicity of NSAIDS and contraindications to regional neuroaxial techniques. Although opioids are widely used post-transplant,…2018 American Transplant Congress
Outpatient Prophylactic Valganciclovir Dose Optimization Post-Renal Transplant
Purpose: Renal function rapidly changes post-transplant requiring dose adjustment of CMV prophylaxis. We describe valganciclovir (VGCV) dosing accuracy in the outpatient setting and its associated…2018 American Transplant Congress
Innovative Strategies to Accommodate Increased Patient Volume in an Outpatient Transplant Infusion Center
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA.
Purpose: To accommodate the increasing volume of patients scheduled for infusions at the Comprehensive Transplant Center(CTC) Infusion suite. It began as a two chair unit…2018 American Transplant Congress
Genome-Wide Association Study of Tacrolimus Dose in Pediatric Solid Organ Transplant Recipients in the CNTRP POSITIVE Study
PURPOSE: There are significant challenges in achieving therapeutic tacrolimus (Tac) concentrations after transplant. We explored variants associated with tacrolimus dose requirements in pediatric solid organ…2018 American Transplant Congress
Cytomegalovirus Prophylaxis Following Alemtuzumab Induction in High Risk Renal Transplant Recipients Experiencing Delayed Graft Function
University of Maryland, Baltimore.
Purpose: There is limited data to support the use of valganciclovir in patients on dialysis. This study assessed the efficacy of valganciclovir 450 mg twice…2017 American Transplant Congress
Association with Tacrolimus Intraindividual Variability, Acute Microinflammation Based on 1 Year-Transplanted Kidney Biopsy After Transplantation, and Biopsy-Proven Acute Rejection.
Surgery, Seoul National University College of Medicine, Seoul, Korea
Background: The purpose of this study was to investigate relationship between tacrolimus intraindividual variability (IIV), acute microinflammation (AMI) based on 1 year-transplanted kidney biopsy, and…
American Transplant Congress abstracts