ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2015 American Transplant Congress

    Establishment of a Novel Model for Hypothermic Machine Perfusion In Vivo in Rabbits

    Z. Zhong,1 Z. Liu,1 R. Wang,1 Z. Fu,2 Y. Zhang,2 Q. Hu,1 K. Jin,1 D. Ko,3 Y. Wang,1 Q. Ye.1,2

    1Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei, China; 2The 3rd Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha, Hunan, China; 3Massachusetts General Hospital, Department of Urology, Boston, MA.

    Background: Hypothermic machine perfusion (MP) could improve outcome after transplantation of DCD kidneys, but protective mechanisms of MP remain largely unknown. Therefore, this study aims…
  • 2015 American Transplant Congress

    Impact of Donor Age on Longterm Outcomes in Asian Kidney Transplant Recipients: A Multicenter Cohort Study

    K. Yoo,1 J. An,2 J.-H. Cho,3 C.-D. Kim,3 S.-K. Park,4 D.-W. Chae,5 Y. Oh,2 C. Lim,2 Y. Kim,1 Y. Kim,6 J. Lee.2

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea; 2Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; 3Internal Medicine, Kyungpook National University Hospital, Daegu, Korea; 4Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; 5Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea; 6Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.

    Background The living donor kidney transplantation (LDKT) is well known for best treatment of end-stage renal disease. Recently, kidney transplantation from elderly living donor has…
  • 2015 American Transplant Congress

    One Year Outcomes and Quality of Life Measurements in 127 Extended Criteria Donor Recipients- A Single Centre Comparative Study

    Y. Tabbakh,1 S. Turner,1 H. Maple,1 C. Callaghan,1 J. Olsburgh,1 F. Calder,1 M. Drage,1 N. Karydis,1 I. Loukopoulos,1 G. Koffman,1 R. Hilton,1 J. Pattison,1 C. Farmer,3 S. Shah,2 E. Spigler,1 N. Mamode,1 N. Kessaris.1

    1Guys Hospital, London, United Kingdom; 2Kings Hospital, London, United Kingdom; 3Kent & Canterbury Hospital, Kent, United Kingdom.

    Introduction: Expanded criteria donors (ECDs) are those aged over 60 or 50-59 with 2 of: hypertension, death from cerebrovascular cause or terminal serum creatinine over…
  • 2015 American Transplant Congress

    Outcomes of Kidney Transplantation from Hypertensive Living Donors

    D.-A. Moutzouris, D. Ellis, K. Koutroutsos, R. Charif, J. Galliford, J. McDermott, D. Taube, M. Loucaidou.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    The disparity between donor kidney availability and demand has increased utilization of kidneys from marginal living donors, including hypertensive donors. The aim of this study…
  • 2015 American Transplant Congress

    Calcineurin Inhibitors (CNI) Minimization Associated With Mammalian Target of Rapamycin Inhibitors (i-mTOR) to Improve Renal Function in Renal Grafts from Uncontrolled Donation After Cardiac Death Donors (UDCDD)

    M. Molina,1 E. Gutierrez,1 S. González-Sanchidrian,2 E. González,1 J. Cabrera,1 N. Polanco,1 A. Hernández,1 A. Sevillano,1 M. Praga,1 A. Andres.1

    1Nephrology, Hospital 12 de Octubre, Madrid, Spain; 2Nephrology, Hospital San Pedro de Alcántara, Caceres, Spain.

    INTRODUCTION: Ischemia injury in kidneys grafts from UDCDD could produce a poor renal function. Minimized blood levels of CNI associated with i-mTOR therapy could avoid…
  • 2015 American Transplant Congress

    Everolimus Versus Mycophenolate for Recipients of Kidney Transplants from Expanded Criteria Donors (ECD) Receiving Anti-Thymocyte Globulin and Tacrolimus

    H. Tedesco-Silva,1 C. Felipe,1 A. Ferreira,1 M. Cristelli,1 A. Bessa,1 P. Ueno,1 T. Sandes- Freitas,1 G. Bassos,1 W. Aguiar,2 H. Proença,3 J. Medina-Pestana.1

    1Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2Urology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 3Pathology, UNIFESP, Sao Paulo, Brazil.

    Introduction: Recipients of kidneys recovered from expanded criteria donors are at higher risk to develop delayed graft function (DGF) and acute rejection (AR), leading to…
  • 2015 American Transplant Congress

    A 10 Min “No-Touch” Time – Is It Enough in DCD? A DCD Animal Study

    M. Sereinigg,1 V. Stadlbauer,2 T. Seifert-Held,3 F. Iberer,1 P. Stiegler.1

    1Department for Transplant Surgery, Medical University Graz, Graz, Austria; 2Department for Gastroenterology and Hepatology, Medical University Graz, Graz, Austria; 3Department for Neurology, Medical University Graz, Graz, Austria.

    Introduction: DCD is under investigation due to the lack of human donor organs. Required times of cardiac arrest vary between 75 seconds and 27 min…
  • 2015 American Transplant Congress

    Enhancing Kidney Function Following DCD Donation With Thrombolytic Therapy: A Preliminary Report of a Multicenter Prospective Quasi-Blinded Randomized Trial

    K. Woodside,1 D. Goldfarb,2 J. Rabets,2 E. Sanchez,1 D. Lebovitz,3 J. Schulak,1 J. Fung,2 B. Eghtesad.2

    1Transplant Institute, University Hospitals Case Medical Center, Cleveland, OH; 2Transplant Center, Cleveland Clinic, Cleveland, OH; 3LIfebanc, Cleveland, OH.

    Kidneys from donors following cardiac death (DCD) are at risk for inferior outcomes, possibly due to microthrombi and additional warm ischemia. We describe an organ…
  • 2015 American Transplant Congress

    Accurate Prediction of High-Resolution HLA-A, -B, -C, -DRB1 and -DQB1 Typing and Low-Resolution HLA-DQA1 Typing by Haplotype Analysis

    A. Jaramillo,1 R. Vaidya,2 M. Pando,3 S. Gaitonde.4

    1Histocompatibility & Immunogenetics Laboratory, Gift of Hope Organ & Tissue Donor Network, Itasca, IL; 2College of Pharmacy, Roseman University of Health Sciences, South Jordan, UT; 3Department of Laboratory Medicine & Pathology, Mayo Clinic, Phoenix, AZ; 4Department of Pathology, University of Illinois, Chicago, IL.

    Aim: Allele-specific HLA antibodies are commonly detected by Luminex single antigen bead assays in solid organ transplant recipients. However, high-resolution HLA typing for deceased donors…
  • 2015 American Transplant Congress

    Survival Outcomes of Kidney Transplant Recipients from Expanded Criteria Donors: A Systematic Review and Meta-Analysis

    A.-H. Querard,1,2,3 F. Gillaizeau,1,3 Y. Foucher,1,3 E. Dantan,3 D. Larmet,1 M. Lorent,3 L.-M. Pouteau,1 C. Combescure,4 M. Giral.1,3,5

    1Institute for Transplantation, Urology and Nephrology, CHU Nantes, Inserm U1064, Nantes University, Nantes, France; 2Centre Hospitalier Départemental de Vendée, La Roche sur Yon, France; 3EA 4275 SPHERE-bioStatistics, Pharmacoepidemiology and Human sciEnces REsearch, Nantes University, Nantes, France; 4CRC & Division of Clinical Epidemiology, Department of Health and Community Medicine, University of Geneva, Geneva, Switzerland; 5LabExTransplantex Nantes, Centre d'Investigation Clinique Biothérapie, Nantes, France.

    Background: In 2002, UNOS proposed the use of Expanded Criteria Donors (ECD=brain dead donor > 60 years, or 50-59 years with two criteria: CVA as…
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