Articles tagged "Donors"

2015 American Transplant Congress
CHBP in Preservation Solution and Autologous Blood Perfusate Ameliorates Ischemia Reperfusion Injury in Isolated Porcine Kidneys
C. Yang,¹ S. Hosgood,² H. Carly,² P. Meeta,² Y. Long,³ T. Zhu,¹ M. Nicholson,² B. Yang.²
¹Urology, Zhongshan Hospital, Fudan University, Shanghai, China; ²Transplant Group, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester General Hospital, Leicester, China; ³Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Background. There is an imperative need to better preserve isolated organs before transplantation. A non-erythropoiesis cyclic helix B peptide (CHBP) derived from erythropoietin was newly…
2015 American Transplant Congress
Protecting Older Patients from Dialysis: The Survival Benefit of Preemptive Transplant With High KDPI Allografts
C. Jay,¹ K. Washburn,¹ P. Dean,² R. Helmick,² M. Stegall.²
¹Transplant Center, University of Texas Health Science Center, San Antonio, TX; ²Department of Surgery, Division of Transplantation, Mayo Clinic, Rochester, MN.
BACKGROUND: Mortality on dialysis remain markedly elevated in patients over 60 years old. Preemptive kidney transplantation (PreKT) represents a means of avoiding the risks of…
2015 American Transplant Congress
Incorporating Markers of Donor Organ Intrinsic Biology Into Donor Quality Evaluation
J. Suh, K. Archer, L. Gallon, I. McConell, A. King, D. Maluf, V. Mas.
UVA, Charlottesville, VA; Northwestern University, Chicago, IL; VCU, Richmond, VA.
Background. We aimed to identify a reliable composite scoring system (clinical / biological) to evalute organ quality and predict outcomes post-kidney transplantation (KT).Methods. 233 deceased…
2015 American Transplant Congress
Increase in Neurologic Determination of Death (NDD) Organ Donation in the Donation After Circulatory Death (DCD) Era. The Ontario Experience
J. Zaltzman,^1,2 J. MacLean,² C. Payne,² E. Paltser,² V. Rao,³ S. Dhanani.^2,4
¹Medicine, Nephrology & Transplant, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada; ²Trillium Gift of Life Network, Ontario, Toronto, ON, Canada; ³Cardiovascular Surgery and Multi-Organ Transplant, University Health Network, University of Toronto, Toronto, ON, Canada; ⁴Pediatric Critical Care, Children's Hospital of Eastern Ontario, Univeristy of Ottawa, Ottawa, ON, Canada.
Some jurisdictions have reported a decrease in neurologic determination of death organ donors (NDD) with the implementation of donation after circulatory death (DCD) organ donation.…
2015 American Transplant Congress
Lung Transplantation from Donors With Kidney Disease
A. Ganapathi, B. Gulack, A. Castleberry, R. Davis, L. Snyder, M. Hartwig.
Duke University Medical Center, Durham, NC.
Background:Various donor characteristics are associated with decreased survival following single (SLT) or bilateral (BLT) lung transplantation. No current studies exist regarding use of lungs from…
2015 American Transplant Congress
Histopathological Criteria for Elevated Risk of Delayed Graft Function in German Pretransplantation Kidney Biopsies from Deceased Donors
J. Becker,¹ B. Eggers,² P. Mertens,³ A. Schwarz,⁴ C. Chatzikyrkou.³
¹Institute of Pathology, University Hospital of Cologne, Cologne, North Rhine-Westfalia, Germany; ²Deutsche Stiftung Organtransplantation, Frankfurt, Hesse, Germany; ³Department of Nephrology and Hypertension, Diabetology and Endocrinology, University Hospital of Magdeburg, Magdeburg, Saxonia-Anhalt, Germany; ⁴Clinic for Nephrology and Hypertension, Hannover Medical School, Hannover, Lower Saxony, Germany.
Introduction:Delayed graft function (DGF) is more frequent with so called marginal kidney donors. Moreover, it is linked to increased recipient mortality and inferior transplant outcome.…
2015 American Transplant Congress
Long-Term Outcomes of Spousal Donor Kidney Transplantation According to the Spousal Relationship
J. Kim,¹ K. Jun,¹ M.-H. Kim,¹ S. Ahn,¹ J. Hwang,¹ S. Kim,¹ S. Park,¹ B. Choi,² S. Kim,² C. Yang,² Y. Kim,² I. Moon.¹
¹Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea; ²Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
We investigated long-term outcomes of spousal donor grafts and factors affecting graft survival in spousal kidney transplantation. Between July 1997 and December 2013, we performed…
2015 American Transplant Congress
The Impact of Cytokine Release Caused By Induction Immunosupression On Nitric Oxide in Renal transplantation
R. Johns,^1,2 M. Laftsidis,² E. Burrows,² F. Edwards,² E. Ablorsu,² P. James,¹ A. Phillips,^1,2 A. Asderakis.²
¹University of Cardiff, Cardiff, United Kingdom; ²University Hospital of Wales, Cardiff, United Kingdom.
IntroductionVarying induction immunosuppression regimens have a differential impact on the pattern of cytokine release. Pro-inflammatory cytokines stimulate endothelial cells causing secretion of NO. Serum nitrite…
2015 American Transplant Congress
Preemptive Deceased Donor Transplant With Kidney Donor Profile Index Scores Greater Than 85 Not Associated With a Survival Benefit
D. Keith, A. Nishio Lucar, G. Vranic.
University of Virginia, Charlottesville, VA.
Preemptively listed candidates for kidney transplant are a unique patient population with regard to marginal quality kidney acceptance as they are not yet dialysis dependent.…
2015 American Transplant Congress
Is Organ Transplantation from Trypanosoma cruzi-Infected Donors Safe? An Autopsy-Based Study of Parasite Persistence in Chronic Chagasic Patients
L. Benvenuti, A. Roggério.
Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil.
Introduction: Chagas' disease, endemic in Latin America, is caused by infection with the protozoan Trypanosoma cruzi. The disease can affect the heart and/or the gastrointestinal…