Articles tagged "Donors"

2018 American Transplant Congress
Impact of Donation after Cardiac Death Allografts on Outcome Following Liver Transplantation for Fulminant Hepatic Failure: An Analysis of the UNOS Database
S. Kumar,¹ S. Lin,² J. Schold.²
¹Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; ²Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
Scarcity of donor organs in liver transplantation (LT) has necessitated consideration of extended criteria donors (ECDs), including donation after cardiac death (DCD) donors. The narrow…
2018 American Transplant Congress
Human Atrial Natriuretic Peptide (hANP) in Cold Storage of Donation after Cardiac Death Livers: A New Tool for Protecting Vascular Endothelia?
Y. Nigmet,¹ K. Hata,¹ Y. Okamura,¹ I. Tamaki,¹ T. Tsuruyama,² H. Hirao,¹ T. Kubota,¹ J. Kusakabe,¹ J. Yoshikawa,¹ T. Goto,¹ T. Tajima,¹ H. Tanaka,¹ S. Uemoto.¹
¹Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University, Kyoto, Japan; ²Center for Anatomical, Pathological, and Forensic Medical Research, Kyoto University, Kyoto, Japan.
Aim: Current critical shortage of donor organs has led to acceptance of donation after cardiac death (DCD) livers for transplantation. Human atrial natriuretic peptide (hANP)…
2018 American Transplant Congress
Lack of Efficacy of Eculizumab for Prevention of Delayed Graft Function (DGF) in Deceased Donor Kidney Transplant Recipients
P. Heeger,¹ E. Akalin,² M. Baweja,¹ R. Bloom,³ S. Florman,¹ B. Haydel,¹ D. Hricik,⁴ S. Kulkarni,⁵ A. Mehrotra,¹ A. Patel,⁶ E. Poggio,⁷ L. Ratner,⁸ S. Schröppel,¹ R. Shapiro.¹
¹Mount Sinai Hosp, NY, NY; ²Montefiore Hosp, NY, NY; ³Hosp U Pa, Phila, PA; ⁴U Hosp Cleveland, Cleveland, OH; ⁵Yale U Hosp, New Haven, CT; ⁶St Barnabas Med Ctr, Livingston, NJ; ⁷Cleveland Clinic, Cleveland, OH; ⁸Columbia-Presbyterian Hosp, NY, NY.
DGF portends poor short- and long-term renal function, increases cost, and may reduce graft survival. We studied the safety/efficacy of eculizumab (ECU), a C5 convertase…
2018 American Transplant Congress
Unilateral vs. Bilateral Dual Kidney Transplantation: University of Bologna Experience
M. Del Gaudio,¹ M. Ravaioli,¹ C. Zanfi,¹ V. Bertuzzo,¹ L. Maroni,¹ G. La Manna,² G. Liviano,² A. Siniscalchi,³ A. D'Errico,⁴ A. Pinna.¹
¹Organ Insufficency and Transplantation/Transplantation Unit Prof. A.D. Pinna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; ²Organ Insufficency and Transplantation Nephrology Unit G. La Manna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; ³Organ Insufficency and Transplantation Intensive Care Unit Prof. S. Faenza, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; ⁴Organ Insufficency and Transplantation Pathology Unit D'Errico, S.Orsola Malpighi Hospital University of Bologna, Bolgona, Italy.
One option for using organs from donors with a suboptimal nephron mass, e.g. expanded criteria donors (ECD) kidneys, is dual kidney transplantation (DKT)Methods: Ninety-three DKT…
2018 American Transplant Congress
Outcomes after Kidney Transplant (KTx) from Deceased Donors (DD) Aged ≥ 70
A. Srinivasan, R. Heilman, H. Khamash, K. Reddy, A. Moss.
Mayo Clinic, Phoenix.
Background:There has been an increase in DD aged 70 or greater and transplant centers are reluctant to accept these organs. The aim of this study…
2018 American Transplant Congress
Transplantation of DCD Livers vs. NDD and LDLT: Is There a Difference in Post-Transplant Kidney Dysfunction?
D. Kollmann,¹ S. Neong,¹ R. Rosales,¹ G. Sapisochin,¹ M. Bhat,¹ M. Cattral,¹ P. Greig,¹ L. Lilly,¹ D. McGilvray,¹ A. Ghanekar,¹ D. Grant,¹ M. Selzner,¹ F. Wong,² N. Selzner.¹
¹Multi Organ Transplant, Toronto General Hospital, Toronto, Canada; ²Division of Gastroenterology, Toronto General Hospital, Toronto, Canada.
Background. Recipients of donation after circulatory death (DCD) grafts are reportedly at higher risk of developing post liver transplant (LT) renal dysfunction. Our aim was…
2018 American Transplant Congress
Landscape of Living Donor Kidney Transplantation with International Donors in the United States
A. Thomas,¹ M. Henderson,¹ A. Shaffer,¹ A. Massie,¹ B. Koons,² K. Lentine,³ D. Segev,¹ F. Al Ammary.¹
¹JHU, Baltimore; ²Villanova University, Villanova; ³SLU, St. Louis.
International living kidney donors (LKDs) can donate to candidates listed in the US. Recently, concerns were raised that international LKD organ-recipients might not achieve the…
2018 American Transplant Congress
Long-Term Kidney Transplant Survival after Deceased-Donor Acute Kidney Injury
I. Hall, E. Akalin, J. Bromberg, M. Doshi, M. Harhay, Y. Jia, S. Mansour, S. Mohan, T. Muthumkumar, P. Reese, B. Schröppel, P. Singh, H. Thiessen-Philbrook, F. Weng, C. Parikh.
Deceased Donor Study Consortium, New Haven, CT.
Purpose: Acute kidney injury (AKI) occurs frequently in deceased donors and is associated with organ discard. Prior studies indicate an association between donor AKI and…
2018 American Transplant Congress
Predictive Scores for Delayed Graft Function Based on Hypothermic Machine Perfusion Variables in Kidney Transplantation
C. Ding,^1,2 W. Xue,^1,2 P. Tian,^1,2 X. Ding,^1,2 X. Pan,^1,2 H. Xiang,^1,2 Y. Li,^1,2 X. Tian,^1,2 F. Han,^1,2 Q. Tai.^1,2
¹Department of Kidney Transplantation, Nephropathy Hospital, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; ²Institute of Organ Transplantation, Xi'an Jiaotong University, Xi'an, China.
Background Hypothermic machine perfusion (HMP) is increasingly being used in cardiac death kidney transplantation, but the value of assessing organ quality and predicting DGF through…
2018 American Transplant Congress
Survival Advantage from Accepting a Circulatory Death Liver Transplant
J. Richards,¹ R. Taylor,² E. Allen,² A. Goh,¹ J. Neuberger,³ D. Collett,² G. Pettigrew.¹
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom; ²Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, United Kingdom; ³Department of Medicine, University of Birmingham, Birmingham, United Kingdom.
Background As liver failure increases in the UK, so does demand for liver transplantation. In response, UK donation after circulatory death (DCD) activity has approximately…