ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors"

  • 2018 American Transplant Congress

    Impact of ELAD C3A Cell Conditioned Medium Enhanced Perfusate Fluid on Functional Recovery of Extended Criteria Donor Livers during Normothermic Machine Perfusion

    S. Afford,2 L. Wallace,2 R. Laing,2 Y. Botteon,2 D. He,3 S. Soundararajan,4 D. Mirza,1 R. Ashley,3 J. Brotherton,3 H. Mergental,1 D. Reich.4

    1Queen Elizabeth Hospital, Birmingham, United Kingdom; 2University of Birmingham, Birmingham, United Kingdom; 3Vital Therapies Inc, San Diego, CA; 4Drexel University, Philadelphia.

    Reconditioning of donor livers by Normothermic Machine Perfusion (NMP) is already increasing the numbers of transplantable organs from the extended criteria donors. The hepatoblastoma-derived cell…
  • 2018 American Transplant Congress

    Donor and Procedural Variability in DCD Liver Transplant: Is It Time to Come to a Consensus?

    L. Ruffolo, M. Balceniuk, R. Hernandez Alejandro.

    Department of Surgery, University of Rochester Medical Center on Behalf of the IDOL Consortium, Rochester, NY.

    Background:Donation after cardiocirculatory death liver transplantation (DCD LT) has re-emerged in part because of insufficient grafts for patients on waiting lists. Unfortunately, DCD LT has…
  • 2018 American Transplant Congress

    A Decade of Dual Kidney Transplantation Reveals Excellent Patient Outcomes from Otherwise Discarded Organs

    I. Rajput, S. Farid, A. Hakeem, M. Jameel, N. Ahmad, O. Masood.

    Department of Organ Transplantation, St. James's University Hospital, Leeds, United Kingdom.

    IntroductionBridging the disparity between the kidney waiting list and donor pool remains challenging. For highly sensitised patients and older recipients the wait is contributing to…
  • 2018 American Transplant Congress

    HLA Typing, Panel Reactive Antibody and Donor Specific Antigen Tests Are Not Necessary for Successful Parathyroid Allotransplantation

    E. Kanimdan,1 B. Goncu,2 Y. Gelmez,3 O. Idiz,4 C. Toka,5 B. Ozdemir,2 H. Basoglu,6 N. Ozten Kandas,7 E. Yucesan,8 Y. Ersoy,5 R. Kazancioglu,9 E. Aysen.5

    1Bezmialem Vakif University, Faculty of Medicine, Department of Medical Biology, Istanbul, Turkey; 2Bezmialem Vakif University, Experimental Research Center, Istanbul, Turkey; 3Istanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Immunology, Istanbul, Turkey; 4Istanbul Training and Research Hospital, Department of General Surgery, Istanbul, Turkey; 5Bezmialem Vakif University, Faculty of Medicine, Department of General Surgery, Istanbul, Turkey; 6Bezmialem Vakif University, Faculty of Medicine, Department of Biophysics, Istanbul, Turkey; 7Bezmialem Vakif University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul, Turkey; 8Bezmialem Vakif University, Institute of Life Sciences and Biotechnology, Istanbul, Turkey; 9Bezmialem Vakif University, Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey.

    Permanent hypoparathyroidism(PH) is incurable condition and requires life long drug therapy.Unique therapeutic option is parathyroid allotransplantation(PA).Some studies use routinely but emprically HLA typing,PRA(panel reactive antibody)…
  • 2018 American Transplant Congress

    Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion

    Y. Boteon,1,2 R. Laing,1,2 A. Schlegel,2 J. Attard,1,2 L. Wallace,1 A. Smith,2 T. Perera,2 J. Isaac,2 D. Mirza,2 S. Afford,1 H. Mergental.2

    1National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; 2Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.

    Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…
  • 2018 American Transplant Congress

    Reducing Discards for Deceased Kidney Donors over Age 50 by Restricting Biopsy Criteria

    C. Hostetler, J. Rogge, B. Nicely, S. Rudich.

    Clinical Division, Gift of Life Michigan, Ann Arbor, MI.

    The placement of kidneys from deceased organ donors of advanced age is an ongoing challenge. An Organ Procurement Organization (OPO) evaluated its discard rate for…
  • 2018 American Transplant Congress

    Factors Associated with the Development of Chronic Kidney Disease after Liver Transplantation

    M. Kalisvaart, A. Schlegel, P. Trivedi, K. Roberts, D. Mirza, T. Perera, J. Isaac, J. Ferguson, P. Muiesan.

    Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.

    BackgroundRenal dysfunction is a common complication after liver transplantation. The increased use of DCD livers has been associated with postoperative acute kidney injury (AKI). However,…
  • 2018 American Transplant Congress

    No Kidney Left Behind: Are We Maximizing Utilization of Deceased Donors with AKI?

    A. Bongu, R. Quillin, M. Chiles, S. Husain, M. Garcia, S. Mohan, L. Ratner.

    Renal Transplantation, Columbia University, New York City, NY.

    Introduction: Kidneys from donors with elevated terminal creatinine (Cr) and acute kidney injury (AKI) can be transplanted safely, yet many of these organs are not…
  • 2018 American Transplant Congress

    The Use of LiMAx for Evaluating Donor Livers on Normothermic Machine Perfusion

    J. Schurink,1 J. de Haan,2 M. Verstegen,1 H. Metselaar,3 J. Ijzermans,1 J. de Jonge.1

    1Surgery, Erasmus MC, Rotterdam, Zuid Holland, Netherlands; 2Intensive Care Medicine, Erasmus MC, Rotterdam, Zuid Holland, Netherlands; 3Gastroenterology, Erasmus MC, Rotterdam, Zuid Holland, Netherlands.

    Due to the organ shortage, inferior quality livers from donors after circulatory arrest (DCD) are offered to relieve mortality on the waiting list. The threshold…
  • 2018 American Transplant Congress

    Do High-Risk Categories Convey the Wrong Message to Waitlisted Patients – Is It Time to Reconsider the Absolute Risk of Graft Loss?

    A. Zarinsefat, H. Braun, S. Syed, B. Orandi, G. Roll.

    Transplant Surgery, UCSF, San Francisco, CA.

    Many waitlisted patients (pts) do not consent to accept livers from “high-risk” donors (HRD), possibly due to lack of understanding of the absolute risk (AR)…
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