ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Donors, non-heart-beating"

  • 2020 American Transplant Congress

    Using an Ex Vivo Blood-Free Model of Preservation and Reperfusion to Evaluate the Effects of Subnormothermic Perfusion with Hydrogen Sulfide on DCD Porcine Renal Grafts

    S. Juriasingani1, A. Ruthirakanthan1, M. Richard-Mohamed2, M. Zhang1, M. Levine1, E. Sogutdelen1, M. Mandurah1, A. Sener1

    1University of Western Ontario, London, ON, Canada, 2London Health Sciences Centre, London, ON, Canada

    *Purpose: The need for donor blood complicates the clinical translation of normothermic and subnormothermic perfusion for preservation and graft function evaluation. As such, hemoglobin-based oxygen…
  • 2020 American Transplant Congress

    One Organ Procurement Organization Coordinates 43% of All Uncontrolled Donation after Circulatory Determination of Death Donors Recovered in the United States Over 24 Years

    R. D. Hasz, S. M. West, H. M. Nathan

    Gift of Life Donor Program, Philadelphia, PA

    *Purpose: An IOM report published in 2006 estimated that 22,000 potential uncontrolled Donation after Circulatory Determination of Death (uDCDD) donors die each year in the…
  • 2020 American Transplant Congress

    The Negative Impact of Inherent Oxidative Stress in Marginal Lungs on Ex Vivo Lung Perfusion

    K. Noda1, B. J. Philips1, M. Velayutham2, T. Harano1, P. Reck dos Santos1, S. Shiva2, P. G. Sanchez1

    1Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, 2Department of Medicine, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Identifying good quality grafts within the donor pool, ex vivo lung perfusion (EVLP) opens another window to evaluate grafts initially declined with marginal quality…
  • 2019 American Transplant Congress

    Effects of Static Subnormothermic Preservation of Extended Warm Ischemic Porcine Kidneys Assessed by Ex-Vivo Machine Perfusion and Renal Transplant Model

    H. Sahara, Y. Ariyoshi, M. Sekijima, T. Iwanaga, A. Shimizu, K. Yamada

    Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan

    *Purpose: The donation after circulatory death (DCD) donors has the potential to match the increasing need for transplantable organs, however, DCD kidneys have a higher…
  • 2019 American Transplant Congress

    Taking a Step toward Standardization: Results of an American Society of Transplant Surgeons/Association of Organ Procurement Organizations Survey of Donation after Circulatory Death Liver Recovery Practices

    M. Hobeika1, R. Glazner2, D. Foley1, S. Hanish1, C. Quintini1, E. Eidbo2, D. Axelrod1

    1American Society of Transplant Surgeons DCD Task Force, Arlington, VA, 2Association of Organ Procurement Organizations, Vienna, VA

    *Purpose: Donation after circulatory death (DCD) liver transplants (LT) represented only 6.3% of total U.S. LT in 2017, despite DCD comprising 18.3% of the deceased…
  • 2019 American Transplant Congress

    Kidney Grafts From Donors After Circulatory Death Provide Comparable Outcome To Donors After Brain Death Without Intracorporeal In Situ Cooling

    H. Harada, M. Miura, A. Mitsuke, H. Higuchi, N. Fukuzawa, H. Tanaka, T. Hirano, T. Seki

    Sapporo City General Hospital, Sapporo, Hokkaido, Japan

    *Purpose: Donation after circulatory death (DCD) had been one and only source of deceased kidney donor in our country. The number of donation after brand…
  • 2019 American Transplant Congress

    The Feasibility Of Donation After Cardiac Death In Liver Transplantation: A Registry Analysis

    A. C. Gruessner, R. Misawa, A. Masi, Z. Moghadamyeghaneh, J. F. Renz, R. W. Gruessner

    SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Utilization of liver allografts from donation after cardiac death (DCD) has gradually increased in the United States. We aimed to analyze overall utilization of…
  • 2019 American Transplant Congress

    Epithelial to Mesenchymal Transition: A Cellular Mediator of Ischemic Cholangiopathy after Liver Transplant

    N. A. Wickramaratne1, R. Li2, R. C. Fyffe-Freil2, T. Tian2, M. J. Mangino2

    1VCUHealth, Richmond, VA, 2Department of Surgery, VCUHealth, Richmond, VA

    *Purpose: Epithelial-to-mesenchymal transition (EMT) is a genetic reprogramming that causes epithelial cells to assume a migratory, mesenchymal phenotype, and it is induced by hypoxia. Ischemic…
  • 2019 American Transplant Congress

    Unfavorable Donor after Cardiac Death Characteristics in Lung Transplantation: An Analysis of the UNOS Registry

    A. Y. Choi1, O. K. Jawitz2, V. Raman2, Y. Barac2, M. S. Mulvihill2, C. Moore2, M. G. Hartwig2

    1Duke University School of Medicine, Durham, NC, 2Department of Surgery, Duke University Medical Center, Durham, NC

    *Purpose: Despite growing evidence that donation after circulatory death (DCD) lung transplants have comparable survival outcomes and primary graft dysfunction rates to donation after brain…
  • 2019 American Transplant Congress

    Hypothermic Machine Perfusion Protects Donation After Cardiac Deathliver Graft Through Gstm1-mediated Cytochrome P450 Exogenous Substance Metabolism Pathway

    W. Liang, S. Ye, Z. Zhong, Q. Hu, Y. Wang, Q. Ye

    Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases, Wuhan, China

    *Purpose: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…
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