Articles tagged "Donors, non-heart-beating"

2020 American Transplant Congress
Nlrp3 Inhibition Improves Heart Graft Function in Donation after Circulatory Death
S. Toldo, E. Mezzaroma, M. Quader
Virginia Commonwealth University, Richmond, VA
*Purpose: Donation after circulatory death (DCD) donors have the potential to increase the number of transplantable hearts, which today relies only on donation after brain…
2020 American Transplant Congress
Proteomics and Metabolomics Technologies Reveal the Effect of Oxygen in Hypothermic Machine Perfusion to Alleviate Donation after Circulatory Death Liver Injury
X. Zeng¹, X. Fan², Y. Wang², Q. Xia¹, J. Liu¹, H. Li¹, Q. Ye², Z. Wang¹
¹Department of Urology, Union Hospital, Affiliated TongJi Medical College, Huazhong University of Science & Technology, Wuhan, China, ²Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Wuhan, China
*Purpose: To compare the effects of oxygenated and nitrogenated hypothermic machine perfusion on the preservation of donation after circulatory death (DCD) livers, and to explore…
2020 American Transplant Congress
Ex-Vivo Perfusion with UW Cold Storage Solution Improves DCD Rat Liver Preservation
R. Fyffe-Freil, N. Wickramaratne, J. Khoraki, H. Kang, C. Chmielewski, R. Li, M. J. Mangino
Surgery, Virginia Commonwealth University, Richmond, VA
*Purpose: The donor pool of livers can be expanded by the successful use of donor livers recovered under DCD conditions. It is assumed that perfusion…
2019 American Transplant Congress
Outcomes of Adult Lung Transplant Recipients of Donation after Circulatory Death Allografts in the US
W. S. Cherikh¹, J. Stehlik², A. Sadavarte¹, D. Van Raemdonck³
¹United Network for Organ Sharing, Richmond, VA, ²University of Utah School of Medicine, Salt Lake City, UT, ³University Hospitals Leuven, Leuven, Belgium
*Purpose: This analysis was performed to compare outcomes of adult lung (LU) transplant (TX) recipients of donation after circulatory death (DCD) and donation after brain…
2019 American Transplant Congress
Transplant Outcomes of DCD Kidneys Recovered with vs. without Pre-Recovery Heparin Administration
J. Narvaez, L. Kayler
Division of Transplantation, University at Buffalo, Buffalo, NY
*Purpose: DCD kidney transplants are associated with higher rates of delayed graft function (DGF) and primary non-function (PNF) likely due to ischemic events during recovery.…
2019 American Transplant Congress
External Validation of the DCD-N Score and a Linear Prediction Model to Identify Potential Candidates for Donation after Circulatory Death: A Nation-Wide Cohort Study
M. F. Nijhoff¹, R. A. Pol¹, M. Volbeda¹, A. M. Kotsopoulos², J. P. Sonneveld³, J. van Dongen⁴, W. F. Abdo⁵, V. Silderhuis⁶, C. Moers¹
¹Surgery – Organ Donation and Transplantation, University Medical Center Groningen, Groningen, Netherlands, ²Department of Intensive Care Unit (ICU), Elisabeth Twee Steden Hospital, Tilburg, Netherlands, ³Department of ICU, Isala, Zwolle, Netherlands, ⁴Department of ICU, Catharina hospital, Eindhoven, Netherlands, ⁵Department of ICU, Radboud University Medical Center, Nijmegen, Netherlands, ⁶Department of ICU, Medisch Spectrum Twente, Enschede, Netherlands
*Purpose: Donation after circulatory death (DCD) is most often a controlled procedure after planned withdrawal of life-sustaining treatment (WLST) at an intensive care unit. In…
2019 American Transplant Congress
Pushing the Limits: A Large Multicentric Case-Control Study Evaluating the Impact of Kidney Transplants from Expanded Criteria Donors after Controlled Circulatory Death the Limits: A Large Multicentric Case-Control Study Evaluating the Impact of Kidney Transplants from Expanded Criteria Donors after Controlled Circulatory Death
N. Toapanta¹, R. Alvarez², G. Lluís³, C. Facundo³, F. Diekmann⁴, I. Revuelta⁴, M. Meneghini², F. Moreso¹, O. Bestard²
¹Kidney Transplantation Unit, Vall d'Hebron University Hospital, Barcelona, Spain, ²Kidney Transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, ³Kidney Transplantation Unit, Puigvert University Hospital, Barcelona, Spain, ⁴Kidney Transplantation Unit, Clinic University Hospital, Barcelona, Spain
*Purpose: Controlled donation after circulatory death (cDCD) has allowed to significantly increase the deceased donors pool. However, while excellent previous reports have been shown using…
2019 American Transplant Congress
Expanding the Donor Pool with Extended Criteria DCD Livers
P. Mihaylov¹, B. Ekser², R. Mangus², J. Fridell², D. Soma², C. Kubal²
¹Indiana Univ School of Medicine, Pavia Univ School of Medicine, Indianapolis, IN, ²Indiana Univ School of Medicine, Indianapolis, IN
*Purpose: Utilization of extended criteria donation after circulatory death (ECD DCD) livers has remained cautious due to potentially worse outcomes because of higher rates of…
2019 American Transplant Congress
The Kidney Donor Profile Index (KDPI) Predicts the Risk of Graft Loss in Patients with a Kidney Transplant from Maastricht Type III Asystolic Donors
V. Lopez Jimenez, C. Casas, P. Ruiz-Esteban, M. Cabello, E. Sola, P. Hidalgo, J. Alonso, M. González-Molina, D. Hernandez
Nephrology, H.R.U Carlos Haya, Málaga, Spain
*Purpose: Recent years have seen an increase in the number of kidney transplants (KT) from Maastricht type III asystolic donors, resulting in the acceptance criteria…
2019 American Transplant Congress
Wide Geographic Variability in the Proportion of Donors with Cardiac Death – Lost Opportunities for Organ Donation?
E. M. Sonnenberg¹, D. S. Goldberg², J. Y. Hsu³, P. P. Reese², P. L. Abt¹
¹Department of Surgery, University of Pennsylvania, Philadelphia, PA, ²Department of Medicine, University of Pennsylvania, Philadelphia, PA, ³Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
*Purpose: Donation after cardiac death (DCD) donors are largely not considered by organ procurement organization (OPO) metrics, as DCD donors are only counted in donor…