2019 American Transplant Congress
Dissecting The Role Of Donor Acute Kidney Injury On Molecular Responses Post-transplantation
*Purpose: In the current scenario of shortage of donor organs, kidneys with AKI are being used and outcome research reports show that the outcomes could…2019 American Transplant Congress
Preoperative Marginal Factors Do Not Affect the Medically Complex Living Donors for Kidney Transplantation
Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan
*Purpose: Recently, medically complex living donors with marginal factors including hypertension, dyslipidemia, glucose intolerance, and obesity are increasing. The impact of preoperative marginal factors on…2019 American Transplant Congress
Listing Practices and Graft Utilization Lag behind Supply of Hepatitis C Positive Deceased Donors for Liver and Kidney Transplant
*Purpose: The opioid epidemic resulted in increasing incidence of hepatitis C (HCV) in the general population and more deceased organ donors with HCV in the…2019 American Transplant Congress
The Degree of Glomerulosclerosis in Procurement Renal Biopsy and its Implications in Predicting Graft Outcomes in Marginal Donor Kidneys
1University of Mississippi Medical Center, Jackson, MS, 2Saint Luke's Health System, Kansas City, MO
*Purpose: Percentage of glomerulosclerosis (GS) is a major determinant for kidney discard. However, GS failed to consistently predict graft outcomes across studies in the literature.…2019 American Transplant Congress
Alpha-1 Antitrypsin Reduces Liver Ischemia Reperfusion Injury during Ex-Vivo Normothermic Machine Perfusion
1Massachusetts General Hospital, Boston, MA, 2Kamada, Rehovot, Israel
*Purpose: Normothermic machine perfusion is an emerging preservation method in liver transplantation with vast potential as a platform for ex-vivo graft reconditioning. Alpha-1 Antitrypsin (AAT)…2019 American Transplant Congress
Pharmacological Enhancement of Bile Duct Preservation and Function during Ex-Situ Normothermic Machine Perfusion
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: Whilst ex-situ normothermic machine perfusion (NMP) of the liver limits the ischaemic injury to the organ, benefits for biliary complications post-transplantation are not yet…2019 American Transplant Congress
The Outcomes of Living Donor Kidney Transplantation in Donors or Recipients with Donors’ Renal Arteriosclerotic Lesions on Preoperative Computed Tomography
*Purpose: Living donor kidney transplantation is being increasingly performed with elderly donors. Such elderly donors often have arteriosclerotic lesions (AS) (Figure 1). Whether the outcomes…2019 American Transplant Congress
The Effect of the Beneficial Activity of α-Lipoic Acid Treatment Depend on the Quality of the Graft Kidneys
*Purpose: In a previous preliminary study, with a small number of patients, we observed that the treatment of the donor and the recipient with the…2019 American Transplant Congress
Machine Perfusion Allows Use of High KDPI and Prolonged Cold Ischemia Time in Deceased Donors: A Single Center Effort to Decrease Discard Rates
Miami Transplant Institute, University of Miami, Miami, FL
*Purpose: Discard rates of deceased donor kidney transplants(DDKT)rises as the kidney donor profile index(KDPI)increases,and approaches 60%for KDPI of >85%.Pulsatile machine perfusion(MP)allows use of kidneys with…2019 American Transplant Congress
Use Of Perirenal Adipose Tissue As A Source Of Donor Cells Allowing Evaluation Of Endothelial Inflammation And Quality Of Expanded Criteria Kidneys
*Purpose: Use of expanded-criteria donor (ECD) kidneys is a perspective to overcome organ shortage. Age and donor-related co-morbidy factors are known to affect graft function…