2016 American Transplant Congress
Cytometric Deep Profiling of the CD8+ T-Cell Compartment in Transplant Patients with CMV Viremia.
Background: Cytomegalovirus (CMV) infection is a common opportunistic viral infection in transplant patients. Patterns of viremia and relapse are influenced by the host immune response,…2016 American Transplant Congress
Do Morbidly Obese Patients Have an Increased Risk of Infection Post-Kidney Transplant?
Medical University of South Carolina, Charleston, SC.
Purpose: Obesity has been associated with significant morbidity in the kidney transplant population. The aim of this study was to assess the impact of obesity…2016 American Transplant Congress
CMV Monitoring Reduces Risk of Clinical Complications in Kidney Transplant Recipients.
MedStar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC.
Objective: Review the advantages of CMV viral load monitoring in preventing CMV associated complications in kidney transplant recipientsMethods: All individuals who underwent a kidney transplant…2016 American Transplant Congress
Assessing Return of CMV Specific Cellular Immunity Using the T-SPOT.CMV Soon After Kidney Transplant with Thymoglobulin.
Infectious Disease, Massachusetts General Hospital, Boston, MA.
Background: We do not currently have sufficient predictive tools to determine risk of CMV infection after organ transplantation. Recent data suggest that assays of the…2016 American Transplant Congress
CMV-Accelerated Cardiac Allograft Rejection Is Associated with Dysregulation of Sphingolipid Metabolomics.
PurposeCytomegalovirus (CMV) infection accelerates transplant vascular sclerosis (TVS) and chronic rejection (CR) in solid organ transplants. Sphingolipid metabolism plays an immunomodulatory role in transplant rejection,…2016 American Transplant Congress
Direct Detection of T and B Memory Lymphocytes Reveals HCMV Exposure That Serum Antibodies Fail to Identify.
Research and Development, Cellular Technology Ltd, Shaker Hts, OH.
It is essential to identify donors who have not been infected with HCMV in order to avoid transmission of HCMV to human recipients of transfusion…2016 American Transplant Congress
Association of Cytomegalovirus-Specific T Cell-Mediated Immunity with the Risk of CMV Infection Occurrence in Kidney Transplant Recipients.
Introduction CMV remains the significant cause of morbidity in transplant recipients. Despite universal prophylaxis, late CMV infection occurs in high proportion of kidney transplant recipients.…2016 American Transplant Congress
Characterization of Resistant Cytomegalovirus in Lung Transplant Recipients in the Modern Era.
NewYork-Presbyterian Hospital, New York, NY.
Cytomegalovirus (CMV) remains a major cause of morbidity and mortality in lung transplant recipients (LTR) and the emergence of resistant CMV (rCMV) has increased. The…2016 American Transplant Congress
Tissue Priming of Plasmacytoid Dendritic Cells Enhances Their Phagocytosis and Lowers the Threshold for Subsequent Toll-Like Receptor 7/9 Activation.
Plasmacytoid dendritic cells (pDC) have a pivotal role in clearing viral infections, and can regulate tolerance or immunity depending on their activation status. We have…2016 American Transplant Congress
Human MicroRNA Responses Are Predictive of CMV Reactivation Following Solid Organ Transplant.
Background: Human microRNA (miRNA) can suppress gene expression through binding to the 3' untranslated region (UTR) of the target mRNA. In silico analysis shows that,…
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