ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "COVID-19"

  • 2022 American Transplant Congress

    Impact of Immunosuppressive Medications on SARS-CoV-2 Vaccination Response in Kidney Transplant Patients

    O. Sogbein1, A. Rizvi2, M. Mujtaba3, M. Kueht4, J. Fair4, A. Gamilla-Crudo3, S. Hussain5

    1Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX, 2Internal Medicine, Nephrology, University of Texas Medical Branch at Galveston, Galveston, TX, 3University of Texas Medical Branch, Galveston, TX, 4Surgery, University of Texas Medical Branch, Galveston, TX, 5University of Texas Medical Branch, Houston, TX

    *Purpose: The COVID-19 pandemic portends significant morbidity and mortality in immunocompromised individuals. Vaccination against COVID-19 among immunocompromised population is an essential step to minimize deadly…
  • 2022 American Transplant Congress

    High TTV Load Before First Vaccine Dose is Associated with Poor Serological Response to Covid-19 Vaccination in Lung Transplant Recipients

    C. C. Van Leer Buter1, R. A. Hoek2, E. A. Verschuuren3, R. D. de Vries4, D. van Baarle1, M. van der Heiden1, H. G. Niesters1, C. GeurtsvanKessel4

    1Dept. of Medical Microbiology, University Medical Center Groningen, Groningen, Netherlands, 2Dept. of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 3Dept. of Pulmonary Diseases,, University Medical Center Groningen, Groningen, Netherlands, 4Dept. of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: Torque tenovirus (TTV), a highly prevalent virus which is not known to cause pathology in humans, is currently being investigated as a marker of…
  • 2022 American Transplant Congress

    Effect of Sars-CoV-2 Delta Variant on Post-Vaccination COVID-19 Infection in Solid Organ Transplant Recipients

    E. Tuttle1, J. Moon2, T. J. Grazia3, T. Sam4, S. Mathai3

    1Pulmonary and Critical Care Department, Baylor University Medical Center, Dallas, TX, 2Department of Internal Medicine, Baylor University Medical Center, Dallas, TX, 3Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX, 4Department of Pharmacy, Baylor University Medical Center, Dallas, TX

    *Purpose: In July 2021, the SARS-CoV-2 Delta variant emerged as the dominant strain in the North Texas area. We reviewed COVID-19 infections post-vaccination in Solid Organ…
  • 2022 American Transplant Congress

    Risk Factors Associated with ICU Admission and Death in Patients Hospitalized with COVID-19 Differ Between Solid Organ Transplant and Non-Solid Organ Transplant Patients

    J. Schaenman, H. Byford, T. R. Grogan, Y. Motwani, O. Beaird, M. Kamath, E. Lum, K. Meneses, D. Sayah, D. Vucicevic, S. Saab

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Despite the large numbers of reports on patient risk factors for poor clinical outcomes with COVID-19, little is known about how these risks may…
  • 2022 American Transplant Congress

    Outcomes of COVID-19 in Solid Organ Transplant Recipients in Canada 2020-2021: A Prospective, Multicenter Cohort Study

    V. G. Hall1, G. Alahmadi2, J. T. Solera2, T. Marinelli2, H. Cardinal3, G. Prasad4, S. A. De Serres5, D. Isaac6, R. Mainra7, C. Lamarche8, R. Sapir-Pichhadze9, S. Gilmour10, A. Humar2, D. Kumar2

    1University Health Network/Toronto General Hospital, Toronto, ON, Canada, 2UHN, Toronto, ON, Canada, 3UMontreal, Montreal, QC, Canada, 4StMH, Toronto, ON, Canada, 5Laval U, Quebec, QC, Canada, 6UCalgary, Calgary, AB, Canada, 7USaskatchewan, Saskatoon, SK, Canada, 8HMR, Montreal, QC, Canada, 9McGill U, Montreal, QC, Canada, 10SCH, Edmonton, AB, Canada

    *Purpose: To understand the outcomes and changes in disease severity of COVID-19 in Solid Organ Transplant (SOT) recipients over time in the context of therapeutic…
  • 2022 American Transplant Congress

    Humoral Response After a Third Dose of Sars-CoV-2 mRNA Vaccine in Transplant Recipients

    A. E. Woolley, N. Sharma, G. Zhou, A. Kim, E. Ryan, M. Joyce, H. Goldberg, M. Givertz, M. Mehra, E. Woodcome, V. Durney, S. Marshall, K. Townsend, A. Coppolino, S. Tullius, S. Malek, H. Mallidi, L. Baden, A. Chandraker

    Brigham & Women's Hospital, Boston, MA

    *Purpose: Prior studies demonstrated an increased immune response post-3rd COVID-19 vaccine dose when given 1-month post-2nd dose in solid organ transplant recipients (SOT). This study…
  • 2022 American Transplant Congress

    Sirolimus Use Is Associated With An Improved Immune Response To Covid-19 Vaccination In Kidney Transplant Recipients

    G. B. Perkins1, M. Tunbridge2, T. Salehi2, C. Chai1, C. M. Hope1, P. Garcia-Valtanen1, J. J. Singer3, P. R. Hurtado2, S. C. Barry1, B. Grubor-Bauk1, P. Hissaria2, S. J. Chadban3, P. Coates1

    1University of Adelaide, Adelaide, Australia, 2Royal Adelaide Hospital, Adelaide, Australia, 3Royal Prince Alfred Hospital, Sydney, Australia

    *Purpose: Kidney transplant recipients (KTRs) are highly vulnerable to severe COVID-19, however are poorly protected by vaccination. Additional vaccine doses have achieved limited improvements in…
  • 2022 American Transplant Congress

    Impact Of Nirmatrelvir-Ritonavir On Tacrolimus Concentrations

    S. Fredrick1, B. Wise2, L. Bowman2, D. DeWolfe1, J. Taylor1, J. Melaragno1

    1University of Rochester Medical Center, Rochester, NY, 2Tampa General Hospital, Tampa, FL

    *Purpose: Ritonavir (RTV), a component of the oral antiviral agent nirmatrelvir-RTV (Paxlovid) for COVID-19 infection, increases tacrolimus concentrations through strong competitive inhibition of gastrointestinal and…
  • 2022 American Transplant Congress

    Immunogenicity and Safety of SARS-CoV-2 Vaccines and Breakthrough Infections Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis

    A. Villavicencio1, Y. Ebisu2, M. Raja3, A. P. Sanchez-Covarrubias1, S. Anjan3, J. M. Reynolds1, J. Simkins3, J. Camargo3, M. I. Morris3, L. Abbo4, G. Guerra5, Y. Natori6

    1Internal Medicine, University of Miami Miller School of Medicine, Miami, FL, 2Kameda Medical Center, Chiba, Japan, 3University of Miami Miller School of Medicine, Miami, FL, 4University Of Miami Miller School of Medicine, Miami, FL, 5University of Miami Jackson Memorial Hospital, Miami, FL, 6University of Miami, Pinecrest, FL

    *Purpose: The SARS-CoV-2 pandemic has had a significant impact on the field of solid organ transplant(SOT). Immunization against SARS-CoV-2 is globally available since 2021. SOT…
  • 2022 American Transplant Congress

    The Prevalence of Anti-SARS-CoV-2 Antibodies After COVID-19 is Similar in Kidney Transplant Recipients to Non-Transplanted Patients, and the Clinical Severity is a Predictor of Seroconversion

    L. R. Requião-Moura, R. Garcia, M. R. Nakamura, R. D. Foresto, V. Gomes, T. Ferreira, I. Meira, M. Cristelli, M. Jesus, R. Rissoni, E. Lucena, H. Tedesco-Silva, J. Medina-Pestana

    Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil

    *Purpose: To evaluate the seroconversion rate in kidney transplant recipients (KTR), compared to two non-transplanted groups of patients, and identify predictors of seroconversion in COVID-19…
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