Articles tagged "COVID-19"

2022 American Transplant Congress
COVID-19 Syndrome After Liver Transplant: Immunosuppression Role and Risk Factors for Mortality
M. M. Pascale¹, F. Frongillo¹, G. Bianco¹, F. Galiandro², E. Nure¹, S. Agnes¹, F. Giovinazzo¹
¹General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, ²General Surgery Unit, ULSS3 Serenissima, Venezia, Italy
*Purpose: Data on mortality and immunosuppression role regarding Liver transplant recipients affected by COVID-19 are still under debate. The present study identified risk factors for…
2022 American Transplant Congress
Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee
L. Danziger-Isakov¹, J. D. Goldman¹, A. Wooley¹, S. Pouch¹, A. Agarwal¹, G. Berry¹, K. Dunn¹, S. Ho¹, M. Kittleson¹, D. H. Lee¹, D. Levine¹, C. Marboe¹, G. Marklin¹, R. Razonable¹, S. Taimur¹, H. Te¹, C. Fox², C. Jett², S. Booker², D. Klassen², R. LaHoz¹
¹OPTN, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
2022 American Transplant Congress
COVID-19 in Solid Organ Transplant: A Global Perspective
.. C19TxR Consortium
ESOT, NHSBT, UNOS, CareDx, South San Francisco, CA
*Purpose: Transplantation has been disrupted dramatically by COVID-19 due to reallocation of healthcare resources and concerns from early reports of increased mortality rates (20-30%) in…
2022 American Transplant Congress
Three Month Antibody Durability and Kinetics in Sars-cov-2 Mrna Vaccinated Heart and Lung Transplant Recipients: Differences Above the Diaphragm
J. L. Alejo¹, J. Ruck¹, T. Chiang¹, A. Abedon¹, J. Kim¹, R. Avery¹, A. Tobian¹, M. Levan¹, D. Warren¹, A. Massie¹, W. Werbel¹, J. Garonzik-Wang², D. Segev¹
¹Johns Hopkins, Baltimore, MD, ²University of Wisconsin, Madison, WI
*Purpose: Heart and lung transplant (HT/LT) recipients have impaired humoral responses to SARS-CoV-2 vaccination compared to other solid organ transplant recipients (SOTRs). The purpose of…
2022 American Transplant Congress
SARS-CoV-2 Antibody Response by mRNA Vaccine Platform in Incrementally Immunosuppressed Patients
J. Mitchell¹, C. Connolly¹, T. Chiang¹, J. Alejo¹, W. Werbel¹, D. Segev¹, A. Massie²
¹Johns Hopkins University, Baltimore, MD, ²Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: This study compares SARS-CoV-2 antibody responses between the two-dose mRNA-1273 and BNT162b2 vaccine series across groups of incrementally immunosuppressed patients.*Methods: Semiquantitative testing for antibodies…
2022 American Transplant Congress
Comparative Outcomes at a Single Center for 71 Deceased Donor Kidney Transplants from Donors with Sars-CoV-2 RNA Detection
C. E. Koval¹, E. Poggio², M. Eltemamy³, Y. Lin², M. Duck⁴, N. Shrestha⁵, A. Wee²
¹Cleveland Clinic Foundation, Cleveland, OH, ²Cleveland Clinic, Cleveland, OH, ³The Cleveland Clinic, Cleveland, OH, ⁴Nephrology, Cleveland Clinic Foundation, Cleveland, OH, ⁵Infectious Diseases, Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Extra-pulmonary organs from donors with SARS-CoV-2 detection during donor evaluation are not accepted by many centers due to theoretical concerns for productive infection and…
2022 American Transplant Congress
Antibody and Cellular Immunity After Primary mRNA Vaccination in Adolescents with Stable Liver or Liver-Inclusive Intestine Allografts
G. Mazariegos¹, C. Ashokkumar², K. Soltys², M. Michaels², G. Bond², A. Khanna², M. Ningappa², P. Morgan², R. Sindhi²
¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA
*Purpose: Transplant recipients experience lower seroconversion rates after COVID-19 vaccination compared with healthy adults and have been prioritized to receive booster doses. To assess pre-…
2022 American Transplant Congress
Kidney Transplantation Utilizing SARS-CoV-2 Rt-PCR Positive Donor Kidneys with Immediate Post Exposure Casirivimab /Imdevimab Followed by Thymoglobulin Induction
S. K. Patel¹, E. Siskind¹, M. Laftavi¹, J. Splinter¹, E. Shipman², S. Shah¹, S. Nijim¹, A. Adekile¹, S. Asad¹
¹Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV, ²Nevada Donor Network, Las Vegas, NV
*Purpose: At the beginning of the pandemic, kidneys from SARS-CoV-2 (COVID) RT-PCR positive donors were not utilized for transplantation, due to the risk of viral…
2022 American Transplant Congress
Humoral and Cellular Immunity 6 Months After SARS-CoV-2 Infection in Solid-Organ Transplant Recipients
S. Morris¹, S. Courel², S. Pallikkuth³, S. Pahwa³, A. Fernandez⁴, S. Anjan¹, G. Guerra⁵, M. Alcaide¹, Y. Natori¹
¹Division of Infectious Disease, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, ²University of Miami Miller School of Medicine, Miami, FL, ³Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, ⁴Infectious Disease Associates of Tampa Bay, Tampa Bay, FL, ⁵University of Miami Jackson Memorial Hospital, Miami, FL
*Purpose: The purpose of this study was to evaluate long term humoral and cellular immunity generated following SARS-CoV-2 infection in solid organ transplant recipients (SOTR).*Methods:…
2022 American Transplant Congress
Re-Infection with SARS-CoV-2 in Solid-Organ Transplant Recipients: Incidence Density and Convalescent Immunity Prior to Re-Infection
S. Morris¹, S. Anjan¹, S. Pallikkuth², P. Frattaroli³, S. Courel⁴, A. Fernandez⁵, A. Natori⁶, L. Abbo⁷, S. Pahwa², G. Guerra⁸, Y. Natori¹
¹Division of Infectious Disease, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, ²Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, ³Medicine, Jackson Memorial Hospital, Miami, FL, ⁴University of Miami Miller School of Medicine, Miami, FL, ⁵Infectious Disease Associates of Tampa Bay, Tampa Bay, FL, ⁶Division of Oncology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, ⁷Division of Infectious Disease, Department of Medicine, University Of Miami Miller School of Medicine, Miami, FL, ⁸Division of Nephrology, Department of Medicine, University of Miami Jackson Memorial Hospital, Miami, FL
*Purpose: The purpose of this study was to study our cohort of adult solid organ transplant recipients who had been infected with SARS-CoV-2 to describe…