2018 American Transplant Congress
The Impact of Rituximab Dose on Hepatitis B Virus Reactivation in HBsAg-Negative/anti-HBc-Positive Kidney Transplant Recipients
Background: Hepatitis B virus (HBV) reactivation is well-recognized complication of rituximab. Although use of rituximab for sensitized patients continues to increase in kidney transplantation, the…2018 American Transplant Congress
The Incidence of Polyomavirus-BK and Cytomegalovirus Infections in Renal Transplant Recipients Following Rituximab Administration
Northwestern Memorial Hospital, Chicago, IL.
Rituximab is an antibody that binds to the CD20 antigen on B cells resulting in rapid and prolonged depletion. At Northwestern Memorial Hospital, a single…2018 American Transplant Congress
Evaluation of FlowDSA Crossmatch for Detection of Donor-Specific HLA Antibodies
Background: Donor-specific HLA antibodies (DSA) are detected by different crossmatch techniques. Flow cytometric crossmatching (FCXM) is sensitive method, but it is subject to false (+)…2018 American Transplant Congress
CD19+ Cell Ratio as a Predictive Marker of Antibody Mediated Rejection in ABO Incompatible Kidney Transplantation
Background: Rituximab has been suggested to deplete B cells and decrease the possibility of antibody mediated rejection (AMR) in ABO-incompatible living kidney transplantation (ABO-ILKT). We…2018 American Transplant Congress
B-Cell Depletion with Rituximab Exacerbates Anti-Donor CD4+ T-Cell Responses in Patients with Donor-Specific Anti-Human Leukocyte Antigen Antibodies
Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
Background: It has been reported that preformed donor-specific anti-human leukocyte antigen antibodies (DSAs) were associated with poor graft outcomes in kidney transplant recipients. To eliminate…2018 American Transplant Congress
Pretransplant Use of Rituximab is Associated with Posttransplant Malignancies Events and Death by Neoplasia in Incompatibility Living Donor Kidney Transplants
Introduction: Incompatibilities is a challenge in kidney transplantation. Potent immunosuppression approach based on desensitization protocols (DS) are usually needed; However, controversies in results and lack…2018 American Transplant Congress
Absence of Rejection in a Facial Allograft Recipient with a Postive Flow Crossmatch 24 Months after Induction with Rabbit Anti-Thymocyte Globulin and Anti-CD20+ Monoclonal Antibody
OBJECTIVE: Vascularized composite allograft (VCA) transplantation has become a feasible reconstructive option for patients with severe facial disfigurement. Short term patient and graft survival have…2017 American Transplant Congress
Desensitization Regimen for the Patients with High Isoagglutinin Titers to Undergo Adult ABO-Incompatible Living Donor Liver Transplantation.
Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Taoyuan, Taiwan
Background: Adult living donor liver transplantation can be performed across ABO blood type barrier successfully by depleting B cells using rituximab. However, the patients with…2017 American Transplant Congress
CXCL13 as a New Systemic Biomarker for B-Cell Involvement in Acute Kidney Allograft Rejection.
The majority of kidney allograft rejections are T cell mediated (TCMR). However, it has been shown that in the presence of B-cell clusters the course…2017 American Transplant Congress
The Effect of Histological Isolated Endarteritis and Solid Endoarteritis Combined with CD20 Positive B Cell Infiltration Appeared in Acute Cellular Rejection on Kidney Allograft Survival.
BackgroundEndarteritis post renal transplantation is regarded as T-cell mediated acute rejection by Banff classification. Recently, results from DNA microarrays suggested that endovasculitis did not represent…
American Transplant Congress abstracts