2019 American Transplant Congress
Innate Immunity in Brain Dead Donors: Implications of Necroptosis in Kidney Allograft Outcomes
*Purpose: Regulated necrosis (necroptosis) has been implicated in renal injury from nephrotoxic agents and ischemia. With the use of suboptimal brain dead donors (BDDs) to…2019 American Transplant Congress
Donor Brain Death Affects Tolerance Induction in Non-Human Primates
*Purpose: Induction of durable allograft acceptance in combined heart/kidney transplantation in non-human primates is possible by applying a mixed chimerism-based conditioning protocol. However, the impact…2019 American Transplant Congress
Organ Donation is an Indication for Renal Replacement Therapy (RRT)
*Purpose: A retrospective review of cases from one large organ procurement organization (OPO) was performed to determine whether the delivery of RRT as a component…2019 American Transplant Congress
Pancreas Transplant Alone Using Donation After Cardiac Death Donors Has Similar Outcomes As Donation After Brain Death Donors
*Purpose: While outcomes of pancreas transplants are improving, there is a persistent hesitancy to use pancreas organs procured in the context of donation after cardiac…2019 American Transplant Congress
Staged Procedure In Simultaneous Liver And Kidney Transplant -the “Swedish” Experience
Transplant Surgery, Swedish Medical Center, Seattle, WA
*Purpose: As many as 30% of liver transplant candidates have renal insufficiency requiring a combined liver and kidney transplantation. The prolonged and complex simultaneous liver-kidney…2019 American Transplant Congress
Donor Management in Donation after Brain Death: A Window of Opportunity – Are Pro-Inflammatory Mediators the Target and What is the Effect of Duration of Brain Death?
*Purpose: Donation after brain death (BD) is a crucial source of transplanted organs - uncertainty remains how duration of BD contributes to outcomes: This study…2018 American Transplant Congress
Targeted Donor Complement Blockade after Brain-Death Prevents Delayed Graft Function but Not Progression to Antibody-Mediated Rejection in a Non-Human Primate Model of Kidney Allo-Transplantation
1Surgery, University of Wisconsin-Madison, Madison, WI; 2Pharming Group N.V, Leiden, Netherlands.
Introduction: Donor brain death (BD) triggers a complement-mediated inflammatory response linked to renal injury which has been associated to delayed graft function (DGF) and the…2018 American Transplant Congress
Unraveling the Neuroimmunological Pathways Surrounding Brain Death: Systematic Study of Clinically Relevant Serum Biomarker Changes during Donor Management from Admission to Procurement
Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Donation after brain death (BD) remains an important source of transplanted organs worldwide and it has been shown that BD causes a hostile environment with…2018 American Transplant Congress
Improving the Organ Donation Referral Process through Telemedicine
1LiveOnNY, NY; 2Northwell Health, New Hyde Park.
Development of a Tele-ICU serving multiple institutions within our donor service area stimulated a collaborative performance improvement project. To improve the referral and timeliness rates…2018 American Transplant Congress
Extended Criteria Donors Have Higher Expression of Inflammatory Genes Than Standard Donors
Background.Changes to an organ occur at the time of brain death where a series of inflammatory modify occur within the organ. Because it is not…
American Transplant Congress abstracts