2019 American Transplant Congress
Staged Procedure In Simultaneous Liver And Kidney Transplant -the “Swedish” Experience
Transplant Surgery, Swedish Medical Center, Seattle, WA
*Purpose: As many as 30% of liver transplant candidates have renal insufficiency requiring a combined liver and kidney transplantation. The prolonged and complex simultaneous liver-kidney…2019 American Transplant Congress
Donor Management in Donation after Brain Death: A Window of Opportunity – Are Pro-Inflammatory Mediators the Target and What is the Effect of Duration of Brain Death?
*Purpose: Donation after brain death (BD) is a crucial source of transplanted organs - uncertainty remains how duration of BD contributes to outcomes: This study…2019 American Transplant Congress
Determinants of Allograft Injury during Procurement in Deceased Donors
*Purpose: With the ever enlarging list of potential recipients on the transplant list, the need for deceased donor organs has become critical. Avoiding injury to…2019 American Transplant Congress
Exendin-4 for Donor Treatment in a Brain-Death Model of Kidney Transplantation
*Purpose: Renal grafts from brain death donors associated with poorer graft outcomes after kidney transplantation, hemodynamic and inflammatory mechanisms can account for brain death induce…2019 American Transplant Congress
Targeting Pyroptosis in Brain-Dead Donors Improves Renal Function after Transplantation in Rat
*Purpose: Pyroptosis is a form of programmed cell death include necrosis, nuclear condensation, and release of proinflammatory after caspase-1 activation. It is unknown whether pyroptosis…2019 American Transplant Congress
Significant Implications of Prior Transplantation on Treatment and Outcomes of Patients Suffering from Traumatic Brain Injury
The University of Toledo Medical Center, Toledo, OH
*Purpose: Recent events in the media and sporting industry highlight traumatic brain injury (TBI) as a major health concern, having implications in many areas of…2018 American Transplant Congress
Targeted Donor Complement Blockade after Brain-Death Prevents Delayed Graft Function but Not Progression to Antibody-Mediated Rejection in a Non-Human Primate Model of Kidney Allo-Transplantation
1Surgery, University of Wisconsin-Madison, Madison, WI; 2Pharming Group N.V, Leiden, Netherlands.
Introduction: Donor brain death (BD) triggers a complement-mediated inflammatory response linked to renal injury which has been associated to delayed graft function (DGF) and the…2018 American Transplant Congress
Unraveling the Neuroimmunological Pathways Surrounding Brain Death: Systematic Study of Clinically Relevant Serum Biomarker Changes during Donor Management from Admission to Procurement
Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Donation after brain death (BD) remains an important source of transplanted organs worldwide and it has been shown that BD causes a hostile environment with…2018 American Transplant Congress
Improving the Organ Donation Referral Process through Telemedicine
1LiveOnNY, NY; 2Northwell Health, New Hyde Park.
Development of a Tele-ICU serving multiple institutions within our donor service area stimulated a collaborative performance improvement project. To improve the referral and timeliness rates…2018 American Transplant Congress
Extended Criteria Donors Have Higher Expression of Inflammatory Genes Than Standard Donors
Background.Changes to an organ occur at the time of brain death where a series of inflammatory modify occur within the organ. Because it is not…