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Articles tagged "Bacterial infection"

  • 2018 American Transplant Congress

    Clostridium Difficile Infection after Liver Transplant is Associated with Poor Long-Term Survival

    A. Ahearn, P. Mahboub, N. Theodoropoulos, B. Movahedi, P. Martins, M. Campion, R. Nathan, A. Bozorgzadeh.

    Division of Organ Transplantation, Umass Memorial Medical Center, Worcester, MA.

    Background: Clostridium Difficile infection (CDI) is a growing problem in hospitalized patients and occurs in liver transplant recipients at a higher rate than non-transplant patients.…
  • 2018 American Transplant Congress

    Infection Outcomes in Solid Organ Transplant Recipients Receiving Trimethoprim-Sulfamethoxazole as Opposed to Atovaquone for Prophylaxis

    A. Drelick,1 W. Mowrey,2 G. Minamoto.3

    1Medicine, Division of Infectious Diseases, Weill Cornell Medical Center, New York, NY; 2Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY; 3Medicine, Division of Infectious Diseases, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY.

    Background: Pneumocystis jiroveci pneumonia (PJP) is an important illness amongst solid organ transplant (SOT) recipients. Trimethoprim-sulfamethoxazole (TMP-SMX) is the prophylaxis of choice based on efficacy…
  • 2018 American Transplant Congress

    Risk Factors and Outcomes with Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Bloodstream Infections among Solid Organ Transplant Recipients

    J. Anesi,1 E. Blumberg,1 E. Lautenbach,1 P. Tamma,2 K. Thom,3 K. Alby,1 W. Bilker,1 J. Omorogbe,1 P. Tolomeo,1 A. Werzen,3 K. Nemati,2 J. Han.1

    1University of Pennsylvania, Philadelphia, PA; 2Johns Hopkins University, Baltimore, MD; 3University of Maryland, Baltimore, MD.

    Objective: Solid organ transplant recipients (SOTR) have been significantly impacted by the emergence of multidrug-resistant bacteria, including extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (EB). We determined the…
  • 2018 American Transplant Congress

    Treatment of Multi-Drug Resistant Gram Negative Infections after Solid Organ Transplant

    M. Heldman, B. Nelson, T. Babu, M. Ison.

    Comprehensive Transplant Center, Northwestern University, Chicago, IL.

    Introduction: Infections with multi-drug resistant (MDR) gram-negative bacilli are associated with significant morbidity and mortality after solid organ transplant. This study characterized patient outcomes related…
  • 2018 American Transplant Congress

    Fosfomycin vs Other Antibiotics for UTI after Kidney Transplant

    O. Mgbako,1 J-.E. Ha,1 N. Topilow,2 E. Min,1 D. Taupin,1 V. Tatapudi,1 B. Gelb,1 S. Hochman.1

    1NYU Langone Health, New York; 2Mt Sinai West, New York.

    Urinary tract infection (UTI) is a frequent infectious complication in kidney transplant recipients (KTRs). Antibiotic resistance is common among urine bacterial isolates in this population.…
  • 2018 American Transplant Congress

    Assessment of Methenamine Hippurate for the Prevention of Recurrent Urinary Tract Infections in Adult Renal Transplant Recipients: A Single Center, Retrospective Study

    I. Hollyer,1 F. Varias,3 B. Ho,1 M. Ison.1

    1Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL; 2Grinnell College, Grinnell, IA.

    Background: Urinary tract infections (UTI) are common in renal transplant recipients (RTR). Methenamine hippurate is a non-antibiotic drug that inhibits bacterial growth in the bladder…
  • 2018 American Transplant Congress

    Association of Tacrolimus Adherence and Discontinuation with Sepsis Risk among Kidney Transplant Recipients

    J. Donnelly,1 P. MacLennan,1 R. Mannon,1 R. Saran,2 J. Baddley,1 H. Wang,3 G. McGwin, Jr.,1 P. Muntner.1

    1University of Alabama at Birmingham, Birmingham, AL; 2University of Michigan, Ann Arbor, MI; 3University of Texas Health Science Center, Houston, TX.

    OBJECTIVE: The association between post-transplant tacrolimus exposure and sepsis risk is currently unknown. We examined the associations of tacrolimus adherence and discontinuation with sepsis risk…
  • 2018 American Transplant Congress

    Outcomes of Renal Transplants from Donors with Positive Blood or Urine Cultures

    L. Chen,1 D. Kamiyama,2 L. Francalacci,1 E. Zhu,2 M. Donnelley,2 N. Clayton,2 K. Alman,1 A. De Mattos,1 J. Brown.3

    1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA; 2Pharmacy, UC Davis Medical Center, Sacramento, CA; 3Infectious Diseases, UC Davis Medical Center, Sacramento, CA.

    OBJECTIVES: To evaluate outcomes in renal transplant recipients who received organs from donors with positive blood or urine cultures.METHODS: We performed a retrospective, single-center study…
  • 2018 American Transplant Congress

    Risk of Bacteremia According to Transplant Induction Immunosuppression Regimen

    E. Misch, S. Kelley, G. Leverson, B. Astor, D. Kaufman.

    University of Wisconsin School of Medicine and Public Health, Madison.

    Background: Transplant immune suppression is designed to suppress the adaptive immune response and ensure graft survival, but may have unintended effects on innate immunity. Few…
  • 2018 American Transplant Congress

    Association of Immunosuppressive Therapy Regimen with Sepsis Outcomes among Kidney Transplant Recipients

    J. Donnelly,1 P. MacLennan,1 R. Mannon,1 R. Saran,2 J. Baddley,1 H. Wang,3 G. McGwin, Jr.,1 P. Muntner.1

    1University of Alabama at Birmingham, Birmingham, AL; 2University of Michigan, Ann Arbor, MI; 3University of Texas Health Science Center, Houston, TX.

    OBJECTIVE: Immunosuppressive therapy (IST) could impact sepsis outcomes by altering the host immune response. We examined the associations of IST regimens with sepsis outcomes among…
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