2019 American Transplant Congress
Blockade of IL-1β and TNF-α Does Not Significantly Pose Risk or Affect Outcomes in Patients Infused with Microbial-Positive Autologous Islet Preparations
*Purpose: We recently demonstrated that the combined use of anakinra (IL-1β blocker) and etanercept (TNF-α blocker) improved outcomes of islet autotransplantation after total pancreatectomy (TPIAT).…2018 American Transplant Congress
Clostridium Difficile Infection after Liver Transplant is Associated with Poor Long-Term Survival
Division of Organ Transplantation, Umass Memorial Medical Center, Worcester, MA.
Background: Clostridium Difficile infection (CDI) is a growing problem in hospitalized patients and occurs in liver transplant recipients at a higher rate than non-transplant patients.…2018 American Transplant Congress
Infection Outcomes in Solid Organ Transplant Recipients Receiving Trimethoprim-Sulfamethoxazole as Opposed to Atovaquone for Prophylaxis
Background: Pneumocystis jiroveci pneumonia (PJP) is an important illness amongst solid organ transplant (SOT) recipients. Trimethoprim-sulfamethoxazole (TMP-SMX) is the prophylaxis of choice based on efficacy…2018 American Transplant Congress
Risk Factors and Outcomes with Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Bloodstream Infections among Solid Organ Transplant Recipients
Objective: Solid organ transplant recipients (SOTR) have been significantly impacted by the emergence of multidrug-resistant bacteria, including extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (EB). We determined the…2018 American Transplant Congress
Treatment of Multi-Drug Resistant Gram Negative Infections after Solid Organ Transplant
Comprehensive Transplant Center, Northwestern University, Chicago, IL.
Introduction: Infections with multi-drug resistant (MDR) gram-negative bacilli are associated with significant morbidity and mortality after solid organ transplant. This study characterized patient outcomes related…2018 American Transplant Congress
Fosfomycin vs Other Antibiotics for UTI after Kidney Transplant
1NYU Langone Health, New York; 2Mt Sinai West, New York.
Urinary tract infection (UTI) is a frequent infectious complication in kidney transplant recipients (KTRs). Antibiotic resistance is common among urine bacterial isolates in this population.…2018 American Transplant Congress
Assessment of Methenamine Hippurate for the Prevention of Recurrent Urinary Tract Infections in Adult Renal Transplant Recipients: A Single Center, Retrospective Study
Background: Urinary tract infections (UTI) are common in renal transplant recipients (RTR). Methenamine hippurate is a non-antibiotic drug that inhibits bacterial growth in the bladder…2018 American Transplant Congress
Association of Tacrolimus Adherence and Discontinuation with Sepsis Risk among Kidney Transplant Recipients
OBJECTIVE: The association between post-transplant tacrolimus exposure and sepsis risk is currently unknown. We examined the associations of tacrolimus adherence and discontinuation with sepsis risk…2018 American Transplant Congress
Outcomes of Renal Transplants from Donors with Positive Blood or Urine Cultures
OBJECTIVES: To evaluate outcomes in renal transplant recipients who received organs from donors with positive blood or urine cultures.METHODS: We performed a retrospective, single-center study…2018 American Transplant Congress
Risk of Bacteremia According to Transplant Induction Immunosuppression Regimen
University of Wisconsin School of Medicine and Public Health, Madison.
Background: Transplant immune suppression is designed to suppress the adaptive immune response and ensure graft survival, but may have unintended effects on innate immunity. Few…
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