Articles tagged "Bacterial infection"

2020 American Transplant Congress
Evaluation of Intraoperative versus Extended Antibiotic Prophylaxis in Liver Transplantation
S. Hamel¹, C. Garza¹, C. Gamble², H. Boone³, L. Thomas⁴, D. L. Gorden⁵
¹Pharmacy, Vanderbilt University Medical Center, Nashville, TN, ²Quality, Vanderbilt Transplant Center, Nashville, TN, ³Vanderbilt University Medical Center, Nashville, TN, ⁴Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, ⁵Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Perioperative antibiotic use has important implications for patient care, antimicrobial stewardship, and cost containment. There is limited data guiding the optimal duration of perioperative…
2020 American Transplant Congress
Incidence of Non-Tuberculous Mycobacteria in the Transplant Population at a University Transplant Center in Northern Florida
D. Schain, Z. Breslow, G. El Helou, A. Cannella
Medicine/IDGM, Univ of Florida, College of Med, Gainesville, FL
*Purpose: Over the past decade, there has been an increase in the number of non-tuberculous mycobacteria (NTM) infections in the United States, especially in the…
2020 American Transplant Congress
Comparative Analysis of Kidney Transplant-Specific versus Hospital-Wide Antibiograms
J. D. Lewis
Medical University of South Carolina, Charleston, SC
*Purpose: Solid organ transplant (SOT) recipients are more likely to develop antimicrobial-resistant infections versus the general population, but few transplant centers have developed SOT-specific antibiograms…
2020 American Transplant Congress
Evaluation Of Typical Renal Transplant Infections In Simultaneous Heart-kidney Transplant Recipients
E. J. Henricksen¹, U. Wang¹, R. Lee¹, R. Imai¹, A. Puing², A. Couture², A. Multani³, Y. Moayedi⁴, C. Lenihan⁵, K. K. Khush⁶, J. J. Teuteberg⁵
¹Pharmacy, Stanford Healthcare, Stanford, CA, ²Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, ³Infectious Diseases, UCLA, Los Angeles, CA, ⁴Cardiology, University Health Network, Toronto, ON, Canada, ⁵Department of Medicine, Stanford University, Stanford, CA, ⁶Medicine, Stanford University, Stanford, CA
*Purpose: Simultaneous heart-kidney transplant (SHKT) is an increasingly utilized treatment for patients with end stage heart failure and advanced kidney disease. Data regarding infectious complications…
2020 American Transplant Congress
Impact of Donor Multidrug-Resistant Organisms on Risk of Recipient Infection
J. A. Anesi¹, E. A. Blumberg¹, J. H. Han², D. H. Lee³, H. Clauss⁴, R. Hasz⁵, E. Molnar⁴, D. Alimenti¹, A. R. Motzer⁴, S. West⁵, W. B. Bilker¹, P. Tolomeo¹, E. Lautenbach¹, T. Prevention Epicenters Program⁶
¹University of Pennsylvania, Philadelphia, PA, ²GlaxoSmithKline, Rockville, MD, ³Drexel University, Philadelphia, PA, ⁴Temple University, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA, ⁶Centers for Disease Control and Prevention, Atlanta, GA
*Purpose: Although there is concern about the use of donor organs that are infected or colonized with multidrug-resistant organisms (MDROs), their impact on solid organ…
2020 American Transplant Congress
Is Azathioprine the Right Choice in De Novo Lung Transplantation?
A. Chan¹, B. Sirandas¹, A. Carlson¹, C. Truax¹, B. Clark¹, I. Hall², B. Cahill³, L. Smith¹
¹Pharmacy, University of Utah Health, Salt Lake City, UT, ²Nephrology, University of Utah Health, Salt Lake City, UT, ³Pulmonary, University of Utah Health, Salt Lake City, UT
*Purpose: The antiproliferative of choice in lung transplantation (LT) remains controversial. Limited data exists on azathioprine (AZA) dose reductions or the conversion of AZA to…
2020 American Transplant Congress
Donor-Derived Gram-Negative Infections in Solid Organ Transplant Recipients: OPTN DTAC Experience, 2012-2018
S. Pouch¹, B. Plucinski², R. La Hoz¹, A. Agarwal¹, S. Aslam¹, L. Danziger-Isakov¹, S. Ho¹, D. Levine¹, M. Malinis¹, M. Rana¹, R. Razonable¹, L. Strasfeld¹, M. Michaels¹
¹OPTN DTAC, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: Rates of Gram-negative (GN) organ donor disease transmission are unknown. Potential donor-derived transmission events (PDDTE) reported to the OPTN Ad hoc Disease Transmission Advisory…
2020 American Transplant Congress
Epidemiology of Clostridioides Difficile Infection in Intestinal and Multivisceral Transplant Patients at a Single Transplant Center
A. Modi¹, B. Gonzalez², K. Brizendine¹
¹Infectious Disease, Cleveland Clinic, Cleveland, OH, ²Pediatric Infectious Disease, Cleveland Clinic, Cleveland, OH
*Purpose: Solid organ transplant (SOT) recipients face increased risk of Clostridioides difficile infection (CDI), with reported CDI incidence of 7.4%-20% far exceeding that of the…
2020 American Transplant Congress
Gut Commensal Microbiota are Associated with a Decreased Risk for Enterobacteriaceae Bacteriuria
J. R. Lee¹, M. Magruder¹, L. Zhang¹, D. Dadhania¹, E. Edusei¹, S. Albakry¹, M. Lubetzky¹, E. Pamer²
¹Medicine / Nephrology and Hypertension, Weill Cornell Medicine, New York, NY, ²University of Chicago, Chicago, IL
*Purpose: Uropathogens from the gut is thought to be a source of bacteriuria and urinary tract infection, but the role of gut commensal microbiota in…
2020 American Transplant Congress
Successful Use of Tedizolid for the Treatment of Nocardiosis in Transplant Recipients
R. Odrobina¹, B. Tritle², C. A.Gomez¹
¹Division of Infectious Diseases, University of Utah, Salt Lake City, UT, ²Department of Pharmacy, University of Utah, Salt Lake City, UT
*Purpose: Nocardiosis is an opportunistic infection occasionally seen after solid organ (SOT) and hematopoietic stem-cell transplantation. Treatment is challenging due to the limited number of…