Articles tagged "Bacterial infection"

2020 American Transplant Congress
Efficacy and Tolerability of Tedizolid Phosphate in the Treatment of Mycobacterium Abscessus Infection among Pediatric Hematopoietic Stem Cell Transplant Recipients
Y. Kang, V. M. Aquino, A. Y. Koh, D. Wetzel, P. K. Sue
Pediatrics, UT Southwestern Medical Center, Dallas, TX
*Purpose: Mycobacterium abscessus complex infections are associated with high rates of morbidity and mortality in immunocompromised hosts. Treatment can be challenging due to broad spectrum…
2020 American Transplant Congress
Risk Factors for Bacterial or Candidal Donor-Derived Infections among Solid Organ Transplant Recipients
J. A. Anesi¹, E. Lautenbach¹, J. H. Han², D. H. Lee³, H. Clauss⁴, R. Hasz⁵, E. Molnar⁴, D. Alimenti¹, A. R. Motzer⁴, S. West⁵, W. B. Bilker¹, P. Tolomeo¹, E. A. Blumberg¹, T. Prevention Epicenters Program⁶
¹University of Pennsylvania, Philadelphia, PA, ²GlaxoSmithKline, Rockville, MD, ³Drexel University, Philadelphia, PA, ⁴Temple University, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA, ⁶Centers for Disease Control and Prevention, Atlanta, GA
*Purpose: Donor-derived infections (DDIs) among solid organ transplant recipients (SOTR) are often associated with significant morbidity and mortality, although the predisposing factors for DDIs remain…
2020 American Transplant Congress
Treatment of Hepatic Encephalopathy in Cirrhotic Patients: Does Rifaximin Prevent Clostridioides Difficile Infection? A Retrospective Analysis
J. D. Goldman, V. Aleksenko, J. L. Davila, N. A. Muhktar, K. Kowdley
Swedish Medical Center, Seattle, WA
*Purpose: Clostridioides difficile infection (CDI) is a major cause of morbidity and mortality and new prevention strategies in high-risk patients are needed. Rifaximin has been…
2020 American Transplant Congress
Use of 16S Sequencing to Reveal Potential Respiratory Pathogens in Lung Transplant Recipients
C. Eskind¹, M. Shilts¹, H. Boone¹, J. Schmitz², C. Shaver³, S. Das¹, G. Satyanarayana¹
¹Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, ²Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, ³Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Respiratory infections are common after lung transplant and contribute to mortality and allograft failure. 16S ribosomal RNA (rRNA) gene sequencing could facilitate diagnosis of…
2020 American Transplant Congress
Transplantation from Donors with Positive Blood Culture
H. Mo, S. Min, H. Ko, C. Chung, H. Kim, A. Han, J. Ha
Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: The use of organs from donors with infection is limited because of the possibility of transmission. Herein we report our experience of transplantation from…
2020 American Transplant Congress
Evaluation of Intraoperative versus Extended Antibiotic Prophylaxis in Liver Transplantation
S. Hamel¹, C. Garza¹, C. Gamble², H. Boone³, L. Thomas⁴, D. L. Gorden⁵
¹Pharmacy, Vanderbilt University Medical Center, Nashville, TN, ²Quality, Vanderbilt Transplant Center, Nashville, TN, ³Vanderbilt University Medical Center, Nashville, TN, ⁴Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, ⁵Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Perioperative antibiotic use has important implications for patient care, antimicrobial stewardship, and cost containment. There is limited data guiding the optimal duration of perioperative…
2020 American Transplant Congress
Incidence of Non-Tuberculous Mycobacteria in the Transplant Population at a University Transplant Center in Northern Florida
D. Schain, Z. Breslow, G. El Helou, A. Cannella
Medicine/IDGM, Univ of Florida, College of Med, Gainesville, FL
*Purpose: Over the past decade, there has been an increase in the number of non-tuberculous mycobacteria (NTM) infections in the United States, especially in the…
2020 American Transplant Congress
Comparative Analysis of Kidney Transplant-Specific versus Hospital-Wide Antibiograms
J. D. Lewis
Medical University of South Carolina, Charleston, SC
*Purpose: Solid organ transplant (SOT) recipients are more likely to develop antimicrobial-resistant infections versus the general population, but few transplant centers have developed SOT-specific antibiograms…
2020 American Transplant Congress
Evaluation Of Typical Renal Transplant Infections In Simultaneous Heart-kidney Transplant Recipients
E. J. Henricksen¹, U. Wang¹, R. Lee¹, R. Imai¹, A. Puing², A. Couture², A. Multani³, Y. Moayedi⁴, C. Lenihan⁵, K. K. Khush⁶, J. J. Teuteberg⁵
¹Pharmacy, Stanford Healthcare, Stanford, CA, ²Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, ³Infectious Diseases, UCLA, Los Angeles, CA, ⁴Cardiology, University Health Network, Toronto, ON, Canada, ⁵Department of Medicine, Stanford University, Stanford, CA, ⁶Medicine, Stanford University, Stanford, CA
*Purpose: Simultaneous heart-kidney transplant (SHKT) is an increasingly utilized treatment for patients with end stage heart failure and advanced kidney disease. Data regarding infectious complications…
2020 American Transplant Congress
Impact of Donor Multidrug-Resistant Organisms on Risk of Recipient Infection
J. A. Anesi¹, E. A. Blumberg¹, J. H. Han², D. H. Lee³, H. Clauss⁴, R. Hasz⁵, E. Molnar⁴, D. Alimenti¹, A. R. Motzer⁴, S. West⁵, W. B. Bilker¹, P. Tolomeo¹, E. Lautenbach¹, T. Prevention Epicenters Program⁶
¹University of Pennsylvania, Philadelphia, PA, ²GlaxoSmithKline, Rockville, MD, ³Drexel University, Philadelphia, PA, ⁴Temple University, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA, ⁶Centers for Disease Control and Prevention, Atlanta, GA
*Purpose: Although there is concern about the use of donor organs that are infected or colonized with multidrug-resistant organisms (MDROs), their impact on solid organ…