Articles tagged "Bacterial infection"

2017 American Transplant Congress
Describing the Effects of the Antibiotic Regimen Immediate Post Multi-Visceral Transplant in the Pediatric Population on the Time to First Serious Bacterial Infection.
B. Chatani,¹ J. Garcia,² C. Biaggi,² T. Beduschi,³ A. Tekin,³ R. Vianna,⁴ I. Gonzalez.⁵
¹Pediatrics, Jackson Memorial Hospital, Miami, FL; ²Pediatric Gastroenterology, University of Miami Miller School of Medicine, Miami, FL; ³Miami Transplant Institute, Miami, FL; ⁴Surgery, University of Miami Miller School of Medicine, Miami, FL; ⁵Pediatric Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL
This study is designed to elucidate the effect a tailored antibiotic regimen administered immediately post multi visceral transplantation may have on the duration until first…
2017 American Transplant Congress
A Novel Role for MyD88 Signaling Downstream from Toll-Like Receptors in B Cells Responding to Blood Group Antigens.
H. Sakai, Y. Tanaka, H. Ohdan.
Hiroshima University, Hiroshima, Japan
[Introduction]Although there is some empirical evidence that severe infectious complications provoke refractory AMR following ABO-incompatible transplantations (ABOi-Tx), its mechanism remains unclear. Here, we investigated a…
2017 American Transplant Congress
Contributing Factors and Impact of Microbial Contamination in Human Islet Isolation and Transplantation.
R. Meier, D. Andrey, N. Niclauss, P. Sun, C. van Delden, B. Bedat, S. Demuylder-Mischler, S. Borot, P.-Y. Benhamou, A. Wojtusciszyn, N. Pernin, Y. Muller, D. Bosco, T. Berney.
Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals and Medical School, Geneva, Switzerland; Division of Infectious Diseases, Department of Medical Specialties, Geneva University Hospitals and Medical School, Geneva, Switzerland
BackgroundThe microbiological safety of islet preparations is of paramount importance. Preservation medium contamination is frequent and its impact on islet yield and function remains unclear.MethodsAll…
2016 American Transplant Congress
Prior Infection or Colonization with Carbapenem-Resistant Enterobacteriaceae Is Not an Absolute Contraindication for Solid Organ Transplantation.
S. Huprikar,¹ L. Casner,¹ S. Pouch,² M. Pinheiro Freire,³ R. Madan,⁴ E. Kwak,⁵ M. Satlin,⁶ P. Hartman,⁷ L. Pisney,⁸ P. Henrique Mourão,⁹ R. La Hoz,¹⁰ G. Patel.¹
¹Mount Sinai, New York; ²Ohio State, Columbus; ³Sao Paulo University, Sao Paulo, Brazil; ⁴Albert Einstein, Bronx; ⁵University of Pittsburgh, Pittsburgh; ⁶Cornell, New York; ⁷Henry Ford Health System, Detroit; ⁸University of Colorado, Denver; ⁹Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; ¹⁰UT Southwestern, Dallas.
BackgroundCarbapenem-resistant Enterobacteriaceae (CRE) infection is associated with poor outcomes after solid organ transplantation (SOT). The significance of CRE colonization or infection prior to SOT is…
2016 American Transplant Congress
Colonization and Risk of Bacteremia by Multi-Drug Resistant Organisms in Intestinal Transplant Recipients.
J. Simkins,¹ J. Camargo,¹ M. Morris,¹ R. Vianna,² T. Beduschi,² L. Abbo.¹
¹Medicine/Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL; ²Surgery, Miami Transplant Institute/University of Miami, Miami, FL.
Background: This study is the first to evaluate colonization rates and subsequent bacteremia with multi-drug resistant organisms (MDRO) in intestinal transplant (ITx) recipients.Methods: Retrospective study…
2016 American Transplant Congress
The Impact of Pre-Transplant Infections on Post-Liver Transplant Outcomes.
S. Ngo, J. Levitsky, M. Ison.
Divisions of Infectious Diseases, Hematology and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL.
Background: Pre- and Post-liver transplant infections are a common cause of morbidity and mortality in orthotopic liver transplant (OLT) patients. How pre-transplant infections affect early…
2016 American Transplant Congress
Clinical Impact of the Verigene® Blood Culture System on Rapid Diagnosis and Antibiotic Optimization in Bacteremic Solid Organ Transplant (SOT) Recipients.
N. Law,¹ G. Malat,^3,4 D. Lee,¹ A. Doyle,² C. Emery,^1,5 K. Kyle,⁵ K. Ranganna,² M. Harhay,² T. Bias.^1,4
¹Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia, PA; ²Division of Nephrology, Drexel University College of Medicine, Philadelphia, PA; ³Department of Surgery, Drexel University College of Medicine, Philadelphia, PA; ⁴Pharmacy, Hahnemann University Hospital, Philadelphia, PA; ⁵Microbiology, Hahnemann University Hospital, Philadelphia, PA.
Background:Bloodstream infections are a major concern in SOT recipients and ineffective antibiotic therapy is strongly associated with poor outcomes. Rapid diagnostic tests (RDT) provide prompt…
2016 American Transplant Congress
Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis: Considerations for Early Intervention.
J. Jolissaint,¹ L. Langman,¹ C. DeBolt,¹ A. Wang,² D. Strand,² V. Zaydfudim,¹ R. Adams,¹ K. Brayman.¹
¹Department of Surgery, University of Virginia, Charlottesville, VA; ²Department of Medicine, University of Virginia, Charlottesville, VA.
Introduction: Total pancreatectomy with islet autotransplantation (TPIAT) provides pain relief for patients with chronic pancreatitis (CP) and the potential to ameliorate the resulting endocrine insufficiency.…
2016 American Transplant Congress
Outcomes Associated with Carbapenem-Resistant Enterobacteriaceae Infection After Solid Organ Transplantation in a Multicenter Study.
S. Huprikar,¹ L. Casner,¹ L. Camera Pierrotti,² A. Nellore,³ R. Madan,⁴ J. Garcia-Diaz,⁵ S. Jacobs,⁶ D. Lee,⁷ W. Trindade Clemente,⁸ G. Alangaden,⁹ R. La Hoz,¹⁰ N. Theodoropoulos,¹¹ M. Miceli,¹² G. Santoro-Lopes,¹³ D. Banach,¹⁴ D. Simon,¹⁵ G. Patel.¹
¹Mount Sinai, New York; ²Univ of Sao Paulo, Sao Paulo, Brazil; ³UAB, Birmingham; ⁴Albert Einstein, Bronx; ⁵Oschner, New Orleans; ⁶Cornell, New York; ⁷Drexel, Philadelphia; ⁸Univ Federal de Minas Gerais, Belo Horizonte, Brazil; ⁹Henry Ford, Detroit; ¹⁰UT Southwestern, Dallas; ¹¹Ohio State, Columbus; ¹²U of Michigan, Ann Arbor; ¹³Federal Univ of Rio de Janeiro, Rio de Janeiro, Brazil; ¹⁴Yale, New Haven; ¹⁵Rush, Chicago.
BackgroundCarbapenem-resistant Enterobacteriaceae infection (CREI) is associated with poor outcomes in solid organ transplant (SOT) recipients but most reports are single center experiences.MethodsPatients who underwent SOT…
2016 American Transplant Congress
Impact of Sarcopenia in Overweight/Obese Recipients on the Outcomes After Adult Living Donor Liver Transplantation.
A. Hammad,^1,2 Y. Hamaguchi,² S. Okumura,² A. Kobayashi,² S. Yagi,² S. Uemoto,² T. Kaido.²
¹Department of Surgery, Mansoura University, Mansoura, Dakahliya, Egypt; ²Division of Hepato-Biliary-Pancreatic and Transplant Surgery Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Background/purpose: The effects of body composition disturbances on liver transplantation outcomes have recently been in focus. However, the effects of obesity, as well as sarcopenic…